5W7C
Human acyloxyacyl hydrolase (AOAH), proteolytically processed, S263A mutant, with LPS
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0050528 | molecular_function | acyloxyacyl hydrolase activity |
| B | 0050528 | molecular_function | acyloxyacyl hydrolase activity |
| C | 0016788 | molecular_function | hydrolase activity, acting on ester bonds |
| C | 0050528 | molecular_function | acyloxyacyl hydrolase activity |
| D | 0016788 | molecular_function | hydrolase activity, acting on ester bonds |
| D | 0050528 | molecular_function | acyloxyacyl hydrolase activity |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: ACT_SITE => ECO:0000305|PubMed:29343645, ECO:0000305|PubMed:8089145 |
| Chain | Residue | Details |
| C | ALA263 | |
| D | ALA263 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 30 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:29343645 |
| Chain | Residue | Details |
| C | ASP184 | |
| C | ASP223 | |
| C | ASP227 | |
| C | ASN229 | |
| C | ASN231 | |
| C | ILE233 | |
| C | GLU245 | |
| D | ASP184 | |
| D | ASP186 | |
| D | ASP188 | |
| D | TYR190 | |
| C | ASP186 | |
| D | ASP205 | |
| D | ASN207 | |
| D | ASP208 | |
| D | ASP210 | |
| D | VAL213 | |
| D | ASP223 | |
| D | ASP227 | |
| D | ASN229 | |
| D | ASN231 | |
| D | ILE233 | |
| C | ASP188 | |
| D | GLU245 | |
| C | TYR190 | |
| C | ASP205 | |
| C | ASN207 | |
| C | ASP208 | |
| C | ASP210 | |
| C | VAL213 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | SITE: Interacts with lipopolysaccharide => ECO:0000250|UniProtKB:O18823 |
| Chain | Residue | Details |
| C | ARG345 | |
| D | ARG345 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:29343645, ECO:0007744|PDB:5W78 |
| Chain | Residue | Details |
| C | ASN207 | |
| C | ASN409 | |
| C | ASN466 | |
| D | ASN207 | |
| D | ASN409 | |
| D | ASN466 |
