5W7B
Rabbit acyloxyacyl hydrolase (AOAH), proteolytically processed, S262A mutant, with LPS
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0050528 | molecular_function | acyloxyacyl hydrolase activity |
| B | 0050528 | molecular_function | acyloxyacyl hydrolase activity |
| C | 0016788 | molecular_function | hydrolase activity, acting on ester bonds |
| C | 0050528 | molecular_function | acyloxyacyl hydrolase activity |
| D | 0016788 | molecular_function | hydrolase activity, acting on ester bonds |
| D | 0050528 | molecular_function | acyloxyacyl hydrolase activity |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 162 |
| Details | Domain: {"description":"Saposin B-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00415","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 64 |
| Details | Region: {"description":"Important for enzyme activity, localization to cytoplasmic vesicles, and protein stability","evidences":[{"source":"UniProtKB","id":"P28039","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"29343645","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5W7B","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 8 |
| Details | Region: {"description":"Lipopolysaccharide binding","evidences":[{"source":"PubMed","id":"29343645","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Active site: {"evidences":[{"source":"PubMed","id":"29343645","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"29343645","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5W7A","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5W7B","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 24 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"29343645","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5W7A","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 4 |
| Details | Site: {"description":"Interacts with lipopolysaccharide","evidences":[{"source":"PubMed","id":"29343645","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
