5W6E
PDE1b complexed with compound 3S
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue ZN A 1001 |
| Chain | Residue |
| A | HIS227 |
| A | HIS263 |
| A | ASP264 |
| A | ASP370 |
| A | HOH1114 |
| A | HOH1221 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 1002 |
| Chain | Residue |
| A | HOH1180 |
| A | HOH1215 |
| A | HOH1295 |
| A | ASP264 |
| A | HOH1114 |
| A | HOH1177 |
| site_id | AC3 |
| Number of Residues | 12 |
| Details | binding site for residue 0NY A 1003 |
| Chain | Residue |
| A | TYR222 |
| A | HIS223 |
| A | HIS373 |
| A | LEU388 |
| A | GLU391 |
| A | PHE392 |
| A | LEU409 |
| A | GLN421 |
| A | PHE424 |
| A | HOH1161 |
| A | HOH1171 |
| A | HOH1263 |
Functional Information from PROSITE/UniProt
| site_id | PS00126 |
| Number of Residues | 12 |
| Details | PDEASE_I_1 3'5'-cyclic nucleotide phosphodiesterase domain signature. HDYeHtGttNsF |
| Chain | Residue | Details |
| A | HIS263-PHE274 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"UniProtKB","id":"O76083","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15260978","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1TAZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NPV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NPW","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
