5W66

RNA polymerase I Initial Transcribing Complex State 3

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Functional Information from GO Data

ChainGOidnamespacecontents
I0005736cellular_componentRNA polymerase I complex
I0003676molecular_functionnucleic acid binding
I0001054molecular_functionRNA polymerase I activity
I0061629molecular_functionRNA polymerase II sequence-specific DNA-binding transcription factor binding
I0008270molecular_functionzinc ion binding
I0006379biological_processmRNA cleavage
I0000122biological_processnegative regulation of transcription by RNA polymerase II
I0042790biological_processnucleolar large rRNA transcription by RNA polymerase I
I0042254biological_processribosome biogenesis
I0006363biological_processtermination of RNA polymerase I transcription
I0006360biological_processtranscription by RNA polymerase I
D0005736cellular_componentRNA polymerase I complex
D0001054molecular_functionRNA polymerase I activity
D0042790biological_processnucleolar large rRNA transcription by RNA polymerase I
D0008361biological_processregulation of cell size
D0042254biological_processribosome biogenesis
D0006360biological_processtranscription by RNA polymerase I
A0042025cellular_componenthost cell nucleus
A0005730cellular_componentnucleolus
A0005736cellular_componentRNA polymerase I complex
A0003677molecular_functionDNA binding
A1990841molecular_functionpromoter-specific chromatin binding
A0001054molecular_functionRNA polymerase I activity
A0008270molecular_functionzinc ion binding
A0042790biological_processnucleolar large rRNA transcription by RNA polymerase I
A0042254biological_processribosome biogenesis
A0006360biological_processtranscription by RNA polymerase I
B0005736cellular_componentRNA polymerase I complex
B0003677molecular_functionDNA binding
B0046872molecular_functionmetal ion binding
B0032549molecular_functionribonucleoside binding
B0001054molecular_functionRNA polymerase I activity
B0042790biological_processnucleolar large rRNA transcription by RNA polymerase I
B0042254biological_processribosome biogenesis
B0006360biological_processtranscription by RNA polymerase I
N0005730cellular_componentnucleolus
N0005634cellular_componentnucleus
N0005736cellular_componentRNA polymerase I complex
N0001054molecular_functionRNA polymerase I activity
N0042790biological_processnucleolar large rRNA transcription by RNA polymerase I
N0042254biological_processribosome biogenesis
N0006360biological_processtranscription by RNA polymerase I
N0006362biological_processtranscription elongation from RNA polymerase I promoter
G0005736cellular_componentRNA polymerase I complex
G0001054molecular_functionRNA polymerase I activity
G0042790biological_processnucleolar large rRNA transcription by RNA polymerase I
G0042254biological_processribosome biogenesis
G0006360biological_processtranscription by RNA polymerase I
M0042025cellular_componenthost cell nucleus
M0005730cellular_componentnucleolus
M0005736cellular_componentRNA polymerase I complex
M0003677molecular_functionDNA binding
M0001054molecular_functionRNA polymerase I activity
M0042790biological_processnucleolar large rRNA transcription by RNA polymerase I
M0008361biological_processregulation of cell size
M0042254biological_processribosome biogenesis
M0001188biological_processRNA polymerase I preinitiation complex assembly
M0006360biological_processtranscription by RNA polymerase I
M0006362biological_processtranscription elongation from RNA polymerase I promoter
E0042025cellular_componenthost cell nucleus
E0005654cellular_componentnucleoplasm
E0005736cellular_componentRNA polymerase I complex
E0005665cellular_componentRNA polymerase II, core complex
E0005666cellular_componentRNA polymerase III complex
E0003677molecular_functionDNA binding
E0001054molecular_functionRNA polymerase I activity
E0042254biological_processribosome biogenesis
E0006386biological_processtermination of RNA polymerase III transcription
E0006360biological_processtranscription by RNA polymerase I
E0006366biological_processtranscription by RNA polymerase II
E0006383biological_processtranscription by RNA polymerase III
E0001172biological_processtranscription, RNA-templated
E0042797biological_processtRNA transcription by RNA polymerase III
F0005737cellular_componentcytoplasm
F0005654cellular_componentnucleoplasm
F0005736cellular_componentRNA polymerase I complex
F0005665cellular_componentRNA polymerase II, core complex
F0005666cellular_componentRNA polymerase III complex
F0003677molecular_functionDNA binding
F0001054molecular_functionRNA polymerase I activity
F0042254biological_processribosome biogenesis
F0006386biological_processtermination of RNA polymerase III transcription
F0006360biological_processtranscription by RNA polymerase I
F0006366biological_processtranscription by RNA polymerase II
F0006383biological_processtranscription by RNA polymerase III
F0001172biological_processtranscription, RNA-templated
F0042797biological_processtRNA transcription by RNA polymerase III
H0005654cellular_componentnucleoplasm
H0005736cellular_componentRNA polymerase I complex
H0005665cellular_componentRNA polymerase II, core complex
H0005666cellular_componentRNA polymerase III complex
H0003677molecular_functionDNA binding
H0001054molecular_functionRNA polymerase I activity
H0042254biological_processribosome biogenesis
H0006386biological_processtermination of RNA polymerase III transcription
H0006360biological_processtranscription by RNA polymerase I
H0006366biological_processtranscription by RNA polymerase II
H0006383biological_processtranscription by RNA polymerase III
H0001172biological_processtranscription, RNA-templated
H0042797biological_processtRNA transcription by RNA polymerase III
L0005737cellular_componentcytoplasm
L0005730cellular_componentnucleolus
L0005654cellular_componentnucleoplasm
L0005634cellular_componentnucleus
L0005736cellular_componentRNA polymerase I complex
L0005665cellular_componentRNA polymerase II, core complex
L0005666cellular_componentRNA polymerase III complex
L0003677molecular_functionDNA binding
L0001054molecular_functionRNA polymerase I activity
L0008270molecular_functionzinc ion binding
L0042254biological_processribosome biogenesis
L0006386biological_processtermination of RNA polymerase III transcription
L0006360biological_processtranscription by RNA polymerase I
L0006366biological_processtranscription by RNA polymerase II
L0006383biological_processtranscription by RNA polymerase III
L0001172biological_processtranscription, RNA-templated
L0042797biological_processtRNA transcription by RNA polymerase III
J0005654cellular_componentnucleoplasm
J0005736cellular_componentRNA polymerase I complex
J0005665cellular_componentRNA polymerase II, core complex
J0005666cellular_componentRNA polymerase III complex
J0003677molecular_functionDNA binding
J0001054molecular_functionRNA polymerase I activity
J0008270molecular_functionzinc ion binding
J0042254biological_processribosome biogenesis
J0006386biological_processtermination of RNA polymerase III transcription
J0006360biological_processtranscription by RNA polymerase I
J0006366biological_processtranscription by RNA polymerase II
J0006383biological_processtranscription by RNA polymerase III
J0001172biological_processtranscription, RNA-templated
J0042797biological_processtRNA transcription by RNA polymerase III
C0005654cellular_componentnucleoplasm
C0005736cellular_componentRNA polymerase I complex
C0005666cellular_componentRNA polymerase III complex
C0003677molecular_functionDNA binding
C0046983molecular_functionprotein dimerization activity
C0001054molecular_functionRNA polymerase I activity
C0042254biological_processribosome biogenesis
C0006386biological_processtermination of RNA polymerase III transcription
C0006360biological_processtranscription by RNA polymerase I
C0070893biological_processtransposon integration
C0042797biological_processtRNA transcription by RNA polymerase III
K0005654cellular_componentnucleoplasm
K0005736cellular_componentRNA polymerase I complex
K0005666cellular_componentRNA polymerase III complex
K0003677molecular_functionDNA binding
K0046983molecular_functionprotein dimerization activity
K0001054molecular_functionRNA polymerase I activity
K0042254biological_processribosome biogenesis
K0006386biological_processtermination of RNA polymerase III transcription
K0006360biological_processtranscription by RNA polymerase I
K0042797biological_processtRNA transcription by RNA polymerase III
Q0005730cellular_componentnucleolus
Q0070860cellular_componentRNA polymerase I core factor complex
Q0001164molecular_functionRNA polymerase I CORE element sequence-specific DNA binding
Q0001181molecular_functionRNA polymerase I general transcription initiation factor activity
Q0017025molecular_functionTBP-class protein binding
Q0042790biological_processnucleolar large rRNA transcription by RNA polymerase I
O0005737cellular_componentcytoplasm
O0070860cellular_componentRNA polymerase I core factor complex
O0001164molecular_functionRNA polymerase I CORE element sequence-specific DNA binding
O0001179molecular_functionRNA polymerase I transcription factor binding
O0001163molecular_functionRNA polymerase I regulatory region sequence-specific DNA binding
O0042790biological_processnucleolar large rRNA transcription by RNA polymerase I
P0005730cellular_componentnucleolus
P0070860cellular_componentRNA polymerase I core factor complex
P0005668cellular_componentRNA polymerase transcription factor SL1 complex
P0046872molecular_functionmetal ion binding
P0001164molecular_functionRNA polymerase I CORE element sequence-specific DNA binding
P0017025molecular_functionTBP-class protein binding
P0042790biological_processnucleolar large rRNA transcription by RNA polymerase I
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Functional Information from PDB Data

site_idNumber of ResiduesDetails
AC15binding site for residue ZN A 1701
ChainResidue
ACYS102
ACYS105
AHIS107
ACYS233
ACYS236

AC25binding site for residue ZN A 1702
ChainResidue
ACYS62
ACYS65
ACYS72
AGLY74
AHIS75

AC35binding site for residue ZN B 1301
ChainResidue
BCYS1104
BGLU1106
BCYS1107
BCYS1128
BCYS1131

AC45binding site for residue ZN I 201
ChainResidue
ICYS10
ICYS13
ICYS30
IGLN32
ICYS33

AC54binding site for residue ZN J 101
ChainResidue
JCYS7
JCYS10
JCYS45
JCYS46

AC64binding site for residue ZN L 101
ChainResidue
LCYS31
LCYS34
LCYS48
LCYS51

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Functional Information from PDB atom coordinates for the "HETATM" binding sites

site_idNumber of ResiduesDetails
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Functional Information from PROSITE/UniProt

site_idNumber of ResiduesDetails
PS0111014RNA polymerases H / 23 Kd subunits signature.H-[NQEIVMYD]-[LIVMYAS]-V-P-[EKT]-H-x(2)-[LIVM]-x(2)-[DESAG]-[ET].
ChainResidueDetails
EHIS147-GLU160

PS0111210RNA polymerases N / 8 Kd subunits signature.[LIVMFD]-[LIVMFP]-P-[LIVM]-x-C-[FL]-[ST]-C-G.
ChainResidueDetails
JILE2-GLY11

PS0111115RNA polymerases K / 14 to 18 Kd subunits signature.[ST]-x-[FY]-E-x-[AT]-R-x-[LIVM]-[GSA]-x-R-[SA]-x-Q.
ChainResidueDetails
FTHR86-GLN100

PS0116613RNA polymerases beta chain signature.G-x-[KN]-[LIVMFA]-[STAC]-[GSTNR]-x-[HSTA]-[GSAI]-[QNH]-K-[GL]-[IVTEC].
ChainResidueDetails
BGLY914-VAL926

PS0044641RNA polymerases D / 30 to 40 Kd subunits signature.N-[SGAT]-[LIVMF]-R-R-x(9)-[SAR]-x(3)-[VA]-x(4)-N-x-[STA]-x(3)-[DN]-E-x-[LIV]-[GSA]-x-R-[LI]-[GAS]-[LIVM](2)-[PV].
ChainResidueDetails
CASN65-PRO105

PS0115432RNA polymerases L / 13 to 16 Kd subunits signature.[LIVMFA]-x(2)-[EYD]-x-[HYN]-[ST]-[LIVMFY]-x-[NSTR]-x-[LIV]-x(3)-[LIVA]-x(4,5)-[VPG]-x(4)-[FY]-x(3)-[HPY]-[PEV].
ChainResidueDetails
KILE65-PRO96

PS0046636Zinc finger TFIIS-type signature.C-x(2)-C-x(9)-[LIVMQSART]-[QH]-[STQLMI]-[RA]-[SACR]-x-[DE]-[DET]-[PGSEAM]-x(6)-C-x(2,5)-C-x(3)-[FWE].
ChainResidueDetails
ICYS86-PHE121

PS0103025RNA polymerases M / 15 Kd subunits signature.[FY]-C-x-[DEKSTG]-C-[GNK]-[DNSA]-[LIVMHG]-[LIVM]-x(8,14)-C-x(1,2)-C.
ChainResidueDetails
IPHE9-CYS33

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Functional Information from SwissProt/UniProt

site_idNumber of ResiduesDetails
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Catalytic Information from CSA

site_idNumber of ResiduesDetails
168889
PDB entries from 2020-09-16