5W5Z

Crystal structure of BAXP168G in complex with an activating antibody at high resolution

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0042981	biological_process	regulation of apoptotic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	binding site for residue EDO L 301

Chain	Residue
L	LYS45
L	PRO59
L	HOH403

---

site_id	AC2
Number of Residues	1
Details	binding site for residue EDO L 302

Chain	Residue
L	SER99

---

site_id	AC3
Number of Residues	4
Details	binding site for residue EDO L 303

Chain	Residue
H	MES303
L	GLN38
L	LEU40
L	THR85

---

site_id	AC4
Number of Residues	8
Details	binding site for residue PG4 L 304

Chain	Residue
L	ASN30
L	LYS31
L	SER67
L	LYS198
L	THR199
L	SER201
L	HOH442
A	ASN104

---

site_id	AC5
Number of Residues	5
Details	binding site for residue PG4 L 305

Chain	Residue
L	ASN52
L	VAL196
L	HIS197
L	LYS198
L	HOH434

---

site_id	AC6
Number of Residues	2
Details	binding site for residue PGE H 301

Chain	Residue
A	GLU44
H	LYS214

---

site_id	AC7
Number of Residues	2
Details	binding site for residue PGE H 302

Chain	Residue
H	TYR107
L	GLY57

---

site_id	AC8
Number of Residues	8
Details	binding site for residue MES H 303

Chain	Residue
H	VAL93
H	GLN110
H	GLY111
H	LYS113
L	GLN38
L	LEU40
L	GLY41
L	EDO303

---

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCEVVH

Chain	Residue	Details
L	TYR191-HIS197

---

site_id	PS01080
Number of Residues	20
Details	BH1 Apoptosis regulator, Bcl-2 family BH1 motif signature. MFsDGnfNWGRVVALFyFAS

Chain	Residue	Details
A	MET99-SER118

---

site_id	PS01258
Number of Residues	12
Details	BH2 Apoptosis regulator, Bcl-2 family BH2 motif signature. WIqdqGGWDgLL

Chain	Residue	Details
A	TRP151-LEU162

---

site_id	PS01259
Number of Residues	15
Details	BH3 Apoptosis regulator, Bcl-2 family BH3 motif signature. LsesLKrIGDELDSN

Chain	Residue	Details
A	LEU59-ASN73

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	14
Details	Motif: {"description":"BH3","evidences":[{"source":"PubMed","id":"8521816","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	20
Details	Motif: {"description":"BH1"}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	15
Details	Motif: {"description":"BH2"}

Chain

Residue

Details

---