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5W4L

Crystal structure of the non-neutralizing and ADCC-potent C11-like antibody N12-i3 in complex with HIV-1 clade A/E gp120, the CD4 mimetic M48U1, and the antibody N5-i5.

Functional Information from GO Data
ChainGOidnamespacecontents
A0019031cellular_componentviral envelope
A0019062biological_processvirion attachment to host cell
A0039654biological_processfusion of virus membrane with host endosome membrane
A0039663biological_processmembrane fusion involved in viral entry into host cell
A0046718biological_processsymbiont entry into host cell
A0055036cellular_componentvirion membrane
A0075509biological_processendocytosis involved in viral entry into host cell
A0075512biological_processclathrin-dependent endocytosis of virus by host cell
G0019031cellular_componentviral envelope
G0019062biological_processvirion attachment to host cell
G0039654biological_processfusion of virus membrane with host endosome membrane
G0039663biological_processmembrane fusion involved in viral entry into host cell
G0046718biological_processsymbiont entry into host cell
G0055036cellular_componentvirion membrane
G0075509biological_processendocytosis involved in viral entry into host cell
G0075512biological_processclathrin-dependent endocytosis of virus by host cell
Functional Information from PROSITE/UniProt
site_idPS00290
Number of Residues7
DetailsIG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH
ChainResidueDetails
ETYR192-HIS198
LTYR192-HIS198
DTYR194-HIS200
HTYR194-HIS200

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PDB entries from 2026-05-27

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