5W3P

ANTIBODY C706 IN COMPLEX WTH BETA-AMYLOID PEPTIDE 1-16

Functional Information from GO Data

Chain	GOid	namespace	contents
P	0016020	cellular_component	membrane

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	binding site for residue SO4 L 301

Chain	Residue
H	PRO9
H	HOH425
L	SER30
L	ARG91
L	HOH476
P	GLU11
P	VAL12
P	HIS14

---

site_id	AC2
Number of Residues	10
Details	binding site for residue GOL L 302

Chain	Residue
H	GLN6
H	SER7
H	GLY8
L	TRP90
L	ARG91
L	SER93
L	HOH410
L	HOH412
P	GLU3
H	GLN5

---

site_id	AC3
Number of Residues	11
Details	binding site for residue GOL L 303

Chain	Residue
H	PHE172
H	PRO173
H	SER183
H	LEU184
H	SER185
L	GLN158
L	SER160
L	SER174
L	SER175
L	THR176
L	HOH407

---

site_id	AC4
Number of Residues	4
Details	binding site for residue SO4 H 301

Chain	Residue
H	PCA1
H	VAL2
H	TYR108
H	HOH452

---

site_id	AC5
Number of Residues	6
Details	binding site for residue GOL H 302

Chain	Residue
H	ARG98
H	SER101
H	TYR108
H	LYS212
H	HOH417
L	ASN150

---

site_id	AC6
Number of Residues	6
Details	binding site for residue SO4 P 901

Chain	Residue
L	HOH422
L	HOH448
P	HIS14
P	GLN15
P	LYS16
P	NH217

---

site_id	AC7
Number of Residues	10
Details	binding site for residue SO4 P 902

Chain	Residue
H	ASN104
L	ARG91
L	HOH408
P	ASP7
P	SER8
P	GLY9
P	TYR10
P	GLU11
P	HOH1007
P	HOH1013

---

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH

Chain	Residue	Details
H	TYR200-HIS206
L	TYR190-HIS196

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:11274207, ECO:0000269|PubMed:26898943

Chain	Residue	Details
P	HIS6
P	HIS14

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	BINDING: BINDING => ECO:0000305|PubMed:10413512, ECO:0000305|PubMed:11274207

Chain	Residue	Details
P	TYR10

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	BINDING: BINDING => ECO:0000269|PubMed:10413512, ECO:0000269|PubMed:11274207, ECO:0000269|PubMed:26898943

Chain	Residue	Details
P	HIS13

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	SITE: Cleavage; by beta-secretase => ECO:0000305|PubMed:11851430

Chain	Residue	Details
P	ACE0

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	SITE: Cleavage; by caspase-6; when associated with variant 670-N-L-671

Chain	Residue	Details
P	ASP1

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	SITE: Cleavage; by ACE => ECO:0000269|PubMed:11604391, ECO:0000269|PubMed:16154999

Chain	Residue	Details
P	ASP7

---

site_id	SWS_FT_FI7
Number of Residues	1
Details	SITE: Cleavage; by alpha-secretase => ECO:0000305|PubMed:11851430

Chain	Residue	Details
P	LYS16

---

site_id	SWS_FT_FI8
Number of Residues	1
Details	CARBOHYD: O-linked (HexNAc...) tyrosine; partial => ECO:0000269|PubMed:22576872

Chain	Residue	Details
P	TYR10

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