5W3P
ANTIBODY C706 IN COMPLEX WTH BETA-AMYLOID PEPTIDE 1-16
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| P | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 L 301 |
| Chain | Residue |
| H | PRO9 |
| H | HOH425 |
| L | SER30 |
| L | ARG91 |
| L | HOH476 |
| P | GLU11 |
| P | VAL12 |
| P | HIS14 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | binding site for residue GOL L 302 |
| Chain | Residue |
| H | GLN6 |
| H | SER7 |
| H | GLY8 |
| L | TRP90 |
| L | ARG91 |
| L | SER93 |
| L | HOH410 |
| L | HOH412 |
| P | GLU3 |
| H | GLN5 |
| site_id | AC3 |
| Number of Residues | 11 |
| Details | binding site for residue GOL L 303 |
| Chain | Residue |
| H | PHE172 |
| H | PRO173 |
| H | SER183 |
| H | LEU184 |
| H | SER185 |
| L | GLN158 |
| L | SER160 |
| L | SER174 |
| L | SER175 |
| L | THR176 |
| L | HOH407 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 H 301 |
| Chain | Residue |
| H | PCA1 |
| H | VAL2 |
| H | TYR108 |
| H | HOH452 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue GOL H 302 |
| Chain | Residue |
| H | ARG98 |
| H | SER101 |
| H | TYR108 |
| H | LYS212 |
| H | HOH417 |
| L | ASN150 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 P 901 |
| Chain | Residue |
| L | HOH422 |
| L | HOH448 |
| P | HIS14 |
| P | GLN15 |
| P | LYS16 |
| P | NH217 |
| site_id | AC7 |
| Number of Residues | 10 |
| Details | binding site for residue SO4 P 902 |
| Chain | Residue |
| H | ASN104 |
| L | ARG91 |
| L | HOH408 |
| P | ASP7 |
| P | SER8 |
| P | GLY9 |
| P | TYR10 |
| P | GLU11 |
| P | HOH1007 |
| P | HOH1013 |
Functional Information from PROSITE/UniProt
| site_id | PS00290 |
| Number of Residues | 7 |
| Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH |
| Chain | Residue | Details |
| H | TYR200-HIS206 | |
| L | TYR190-HIS196 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"11274207","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26898943","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"10413512","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"11274207","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"10413512","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"11274207","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26898943","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Site: {"description":"Cleavage; by caspase-6; when associated with variant 670-N-L-671"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Site: {"description":"Cleavage; by ACE","evidences":[{"source":"PubMed","id":"11604391","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16154999","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"O-linked (HexNAc...) tyrosine; partial","evidences":[{"source":"PubMed","id":"22576872","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
