5W2J

Crystal structure of dimeric form of mouse Glutaminase C

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004359	molecular_function	glutaminase activity
A	0006541	biological_process	glutamine metabolic process
B	0004359	molecular_function	glutaminase activity
B	0006541	biological_process	glutamine metabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue CL A 601

Chain	Residue
A	GLN290
A	SER291
A	TYR471
A	GLY488
A	VAL489
A	HOH753

---

site_id	AC2
Number of Residues	5
Details	binding site for residue CL B 601

Chain	Residue
B	GLY488
B	VAL489
B	GLN290
B	SER291
B	TYR471

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	14
Details	BINDING: BINDING => ECO:0000269|PubMed:22228304, ECO:0007744|PDB:3SS5

Chain	Residue	Details
A	SER291
B	GLU386
B	ASN393
B	TYR419
B	TYR471
B	VAL489
A	ASN340
A	GLU386
A	ASN393
A	TYR419
A	TYR471
A	VAL489
B	SER291
B	ASN340

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	MOD_RES: N6-succinyllysine => ECO:0007744|PubMed:23806337

Chain	Residue	Details
A	LYS169
B	LYS169

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:O94925

Chain	Residue	Details
A	LYS316
B	LYS316

---