5W1H

Crystal structure of LbaCas13a (C2c2) bound to mature crRNA (24-nt spacer)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003723	molecular_function	RNA binding
A	0004518	molecular_function	nuclease activity
A	0004519	molecular_function	endonuclease activity
A	0016787	molecular_function	hydrolase activity
A	0051607	biological_process	defense response to virus

Functional Information from PDB Data

site_id	AC1
Number of Residues	1
Details	binding site for residue IOD A 1502

Chain	Residue
A	ARG1126

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site_id	AC2
Number of Residues	1
Details	binding site for residue IOD A 1503

Chain	Residue
A	PRO886

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site_id	AC3
Number of Residues	1
Details	binding site for residue IOD A 1504

Chain	Residue
A	ASP210

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site_id	AC4
Number of Residues	1
Details	binding site for residue IOD A 1505

Chain	Residue
A	ARG848

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site_id	AC5
Number of Residues	2
Details	binding site for residue IOD A 1506

Chain	Residue
A	LYS528
A	SER1201

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site_id	AC6
Number of Residues	1
Details	binding site for residue IOD A 1508

Chain	Residue
A	PHE524

---

site_id	AC7
Number of Residues	1
Details	binding site for residue IOD A 1509

Chain	Residue
A	LYS615

---

site_id	AC8
Number of Residues	1
Details	binding site for residue IOD A 1510

Chain	Residue
A	LYS321

---

site_id	AC9
Number of Residues	1
Details	binding site for residue IOD A 1511

Chain	Residue
A	LYS340

---

site_id	AD1
Number of Residues	1
Details	binding site for residue IOD A 1512

Chain	Residue
A	LYS1069

---

site_id	AD2
Number of Residues	1
Details	binding site for residue IOD A 1514

Chain	Residue
A	GLN1158

---

site_id	AD3
Number of Residues	3
Details	binding site for residue IOD A 1515

Chain	Residue
A	THR633
A	VAL634
A	ALA881

---

site_id	AD4
Number of Residues	1
Details	binding site for residue IOD A 1518

Chain	Residue
A	ARG1211

---

site_id	AD5
Number of Residues	1
Details	binding site for residue IOD A 1519

Chain	Residue
A	ARG1362

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site_id	AD6
Number of Residues	1
Details	binding site for residue IOD A 1520

Chain	Residue
A	ASP1350

---

site_id	AD7
Number of Residues	2
Details	binding site for residue IOD A 1521

Chain	Residue
A	PHE575
A	ASP576

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site_id	AD8
Number of Residues	1
Details	binding site for residue IOD A 1522

Chain	Residue
A	ASP393

---

site_id	AD9
Number of Residues	4
Details	binding site for residue GOL A 1524

Chain	Residue
A	GLY1261
A	ALA1323
A	ARG1324
A	HOH1891

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site_id	AE1
Number of Residues	5
Details	binding site for residue GOL A 1525

Chain	Residue
A	LEU687
A	ASN693
A	ARG848
A	LYS849
A	LEU852

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site_id	AE2
Number of Residues	7
Details	binding site for residue GOL A 1526

Chain	Residue
A	ALA669
A	GLN804
A	GLN807
A	LYS926
A	TRP930
A	HOH1622
A	HOH1646

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