Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004517 | molecular_function | nitric-oxide synthase activity |
A | 0006809 | biological_process | nitric oxide biosynthetic process |
B | 0004517 | molecular_function | nitric-oxide synthase activity |
B | 0006809 | biological_process | nitric oxide biosynthetic process |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 17 |
Details | binding site for residue HEM A 801 |
Chain | Residue |
A | TRP414 |
A | PHE709 |
A | TYR711 |
A | H4B802 |
A | 9P4803 |
A | HOH909 |
A | HOH937 |
A | HOH975 |
A | HOH1068 |
A | ALA417 |
A | ARG419 |
A | CYS420 |
A | PHE589 |
A | SER590 |
A | TRP592 |
A | GLU597 |
A | TRP683 |
site_id | AC2 |
Number of Residues | 15 |
Details | binding site for residue H4B A 802 |
Chain | Residue |
A | SER339 |
A | ARG601 |
A | VAL682 |
A | TRP683 |
A | HEM801 |
A | HOH931 |
A | HOH938 |
A | HOH975 |
A | HOH1040 |
A | HOH1069 |
B | TRP681 |
B | PHE696 |
B | HIS697 |
B | GLN698 |
B | GLU699 |
site_id | AC3 |
Number of Residues | 8 |
Details | binding site for residue 9P4 A 803 |
Chain | Residue |
A | MET341 |
A | HIS342 |
A | VAL572 |
A | TRP592 |
A | GLU597 |
A | HEM801 |
A | HOH909 |
A | HOH1145 |
site_id | AC4 |
Number of Residues | 4 |
Details | binding site for residue ZN A 804 |
Chain | Residue |
A | CYS331 |
A | CYS336 |
B | CYS331 |
B | CYS336 |
site_id | AC5 |
Number of Residues | 17 |
Details | binding site for residue HEM B 801 |
Chain | Residue |
B | TRP414 |
B | ARG419 |
B | CYS420 |
B | SER462 |
B | PHE589 |
B | SER590 |
B | TRP592 |
B | GLU597 |
B | TRP683 |
B | PHE709 |
B | TYR711 |
B | H4B802 |
B | 9P4803 |
B | HOH910 |
B | HOH917 |
B | HOH944 |
B | HOH967 |
site_id | AC6 |
Number of Residues | 16 |
Details | binding site for residue H4B B 802 |
Chain | Residue |
A | TRP681 |
A | PHE696 |
A | HIS697 |
A | GLN698 |
A | GLU699 |
B | SER339 |
B | MET341 |
B | ARG601 |
B | VAL682 |
B | TRP683 |
B | HEM801 |
B | HOH942 |
B | HOH944 |
B | HOH955 |
B | HOH992 |
B | HOH1009 |
site_id | AC7 |
Number of Residues | 8 |
Details | binding site for residue 9P4 B 803 |
Chain | Residue |
A | TRP311 |
B | MET341 |
B | HIS342 |
B | VAL572 |
B | TRP592 |
B | GLU597 |
B | HEM801 |
B | HOH967 |
Functional Information from PROSITE/UniProt
site_id | PS60001 |
Number of Residues | 8 |
Details | NOS Nitric oxide synthase (NOS) signature. RCVGRIqW |
Chain | Residue | Details |
A | ARG419-TRP426 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | SER339 | |
B | SER339 | |
B | GLN483 | |
B | TRP592 | |
B | TYR593 | |
B | GLU597 | |
B | VAL682 | |
B | TRP683 | |
B | PHE696 | |
B | TYR711 | |
A | GLN483 | |
A | TRP592 | |
A | TYR593 | |
A | GLU597 | |
A | VAL682 | |
A | TRP683 | |
A | PHE696 | |
A | TYR711 | |
Chain | Residue | Details |
A | CYS420 | |
B | CYS420 | |