5VRE
Crystal structure of a lysosomal potassium-selective channel TMEM175 homolog from Chamaesiphon Minutus
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005267 | molecular_function | potassium channel activity |
| A | 0006811 | biological_process | monoatomic ion transport |
| A | 0006813 | biological_process | potassium ion transport |
| A | 0015252 | molecular_function | proton channel activity |
| A | 0016020 | cellular_component | membrane |
| A | 0034220 | biological_process | monoatomic ion transmembrane transport |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0051289 | biological_process | protein homotetramerization |
| A | 0071805 | biological_process | potassium ion transmembrane transport |
| A | 1902600 | biological_process | proton transmembrane transport |
| B | 0005267 | molecular_function | potassium channel activity |
| B | 0006811 | biological_process | monoatomic ion transport |
| B | 0006813 | biological_process | potassium ion transport |
| B | 0015252 | molecular_function | proton channel activity |
| B | 0016020 | cellular_component | membrane |
| B | 0034220 | biological_process | monoatomic ion transmembrane transport |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0051289 | biological_process | protein homotetramerization |
| B | 0071805 | biological_process | potassium ion transmembrane transport |
| B | 1902600 | biological_process | proton transmembrane transport |
| C | 0005267 | molecular_function | potassium channel activity |
| C | 0006811 | biological_process | monoatomic ion transport |
| C | 0006813 | biological_process | potassium ion transport |
| C | 0015252 | molecular_function | proton channel activity |
| C | 0016020 | cellular_component | membrane |
| C | 0034220 | biological_process | monoatomic ion transmembrane transport |
| C | 0042802 | molecular_function | identical protein binding |
| C | 0051289 | biological_process | protein homotetramerization |
| C | 0071805 | biological_process | potassium ion transmembrane transport |
| C | 1902600 | biological_process | proton transmembrane transport |
| D | 0005267 | molecular_function | potassium channel activity |
| D | 0006811 | biological_process | monoatomic ion transport |
| D | 0006813 | biological_process | potassium ion transport |
| D | 0015252 | molecular_function | proton channel activity |
| D | 0016020 | cellular_component | membrane |
| D | 0034220 | biological_process | monoatomic ion transmembrane transport |
| D | 0042802 | molecular_function | identical protein binding |
| D | 0051289 | biological_process | protein homotetramerization |
| D | 0071805 | biological_process | potassium ion transmembrane transport |
| D | 1902600 | biological_process | proton transmembrane transport |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 92 |
| Details | Transmembrane: {"description":"Helical; Name=TM1","evidences":[{"source":"PubMed","id":"28723891","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 108 |
| Details | Topological domain: {"description":"Extracellular","evidences":[{"source":"PubMed","id":"28723891","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 100 |
| Details | Transmembrane: {"description":"Helical; Name=TM2","evidences":[{"source":"PubMed","id":"28723891","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 32 |
| Details | Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"28723891","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 100 |
| Details | Transmembrane: {"description":"Helical; Name=TM3","evidences":[{"source":"PubMed","id":"28723891","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 96 |
| Details | Transmembrane: {"description":"Helical; Name=TM4","evidences":[{"source":"PubMed","id":"28723891","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 104 |
| Details | Transmembrane: {"description":"Helical; Name=TM5","evidences":[{"source":"PubMed","id":"28723891","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 60 |
| Details | Transmembrane: {"description":"Helical; Name=TM6","evidences":[{"source":"PubMed","id":"28723891","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 20 |
| Details | Region: {"description":"Short helix H1","evidences":[{"source":"PubMed","id":"28723891","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 24 |
| Details | Region: {"description":"Short helix H2","evidences":[{"source":"PubMed","id":"28723891","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 24 |
| Details | Motif: {"description":"RxxxFSD motif","evidences":[{"source":"PubMed","id":"28723891","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI12 |
| Number of Residues | 4 |
| Details | Site: {"description":"Hydrophobic filter residue 1","evidences":[{"source":"PubMed","id":"28723891","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI13 |
| Number of Residues | 4 |
| Details | Site: {"description":"Hydrophobic filter residue 2","evidences":[{"source":"PubMed","id":"28723891","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI14 |
| Number of Residues | 4 |
| Details | Site: {"description":"Hydrophobic filter residue 3","evidences":[{"source":"PubMed","id":"28723891","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
