5VRB

Crystal structure of a transketolase from Neisseria gonorrhoeae

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0004802	molecular_function	transketolase activity
A	0005829	cellular_component	cytosol
A	0006098	biological_process	pentose-phosphate shunt
A	0016740	molecular_function	transferase activity
A	0016744	molecular_function	transketolase or transaldolase activity
A	0046872	molecular_function	metal ion binding
B	0003824	molecular_function	catalytic activity
B	0004802	molecular_function	transketolase activity
B	0005829	cellular_component	cytosol
B	0006098	biological_process	pentose-phosphate shunt
B	0016740	molecular_function	transferase activity
B	0016744	molecular_function	transketolase or transaldolase activity
B	0046872	molecular_function	metal ion binding
C	0003824	molecular_function	catalytic activity
C	0004802	molecular_function	transketolase activity
C	0005829	cellular_component	cytosol
C	0006098	biological_process	pentose-phosphate shunt
C	0016740	molecular_function	transferase activity
C	0016744	molecular_function	transketolase or transaldolase activity
C	0046872	molecular_function	metal ion binding
D	0003824	molecular_function	catalytic activity
D	0004802	molecular_function	transketolase activity
D	0005829	cellular_component	cytosol
D	0006098	biological_process	pentose-phosphate shunt
D	0016740	molecular_function	transferase activity
D	0016744	molecular_function	transketolase or transaldolase activity
D	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue EDO A 701

Chain	Residue
A	SER556
A	GLU557
A	PHE641
A	PHE646
A	HOH997
A	HOH1018

---

site_id	AC2
Number of Residues	7
Details	binding site for residue CA A 702

Chain	Residue
A	HOH1196
B	HOH1000
B	HOH1201
B	HOH1339
A	GLU633
A	HOH1152
A	HOH1181

---

site_id	AC3
Number of Residues	5
Details	binding site for residue CA A 703

Chain	Residue
A	ASP152
A	ASN182
A	ASN183
A	HOH842
A	HOH1206

---

site_id	AC4
Number of Residues	4
Details	binding site for residue CA A 704

Chain	Residue
A	GLY151
A	ASP152
A	GLY153
A	OCS154

---

site_id	AC5
Number of Residues	7
Details	binding site for residue CA B 701

Chain	Residue
A	HOH906
A	HOH1157
A	HOH1252
B	GLU633
B	HOH1217
B	HOH1261
B	HOH1271

---

site_id	AC6
Number of Residues	6
Details	binding site for residue CA B 702

Chain	Residue
B	ASP152
B	ASN182
B	ILE184
B	HOH998
B	HOH1242
B	HOH1281

---

site_id	AC7
Number of Residues	3
Details	binding site for residue CA B 703

Chain	Residue
B	GLY153
B	OCS154
B	HOH1281

---

site_id	AC8
Number of Residues	7
Details	binding site for residue EDO C 701

Chain	Residue
C	ASP386
C	SER390
C	SER392
C	TYR401
C	CA703
C	HOH869
C	HOH1095

---

site_id	AC9
Number of Residues	9
Details	binding site for residue EDO C 702

Chain	Residue
C	VAL406
C	GLU408
C	PHE434
C	HOH816
C	HOH823
D	GLY111
D	PRO112
D	LEU113
D	GLU157

---

site_id	AD1
Number of Residues	6
Details	binding site for residue CA C 703

Chain	Residue
C	SER390
C	EDO701
C	HOH869
C	HOH1095
C	HOH1098
C	HOH1192

---

site_id	AD2
Number of Residues	7
Details	binding site for residue CA C 704

Chain	Residue
C	GLU633
C	HOH1162
C	HOH1187
C	HOH1188
C	HOH1199
D	HOH875
D	HOH1222

---

site_id	AD3
Number of Residues	5
Details	binding site for residue CA C 705

Chain	Residue
C	ASP152
C	ASN182
C	ASN183
C	HOH893
C	HOH1212

---

site_id	AD4
Number of Residues	6
Details	binding site for residue EDO D 701

Chain	Residue
D	ASP386
D	SER390
D	SER392
D	TYR401
D	CA706
D	HOH1031

---

site_id	AD5
Number of Residues	7
Details	binding site for residue EDO D 702

Chain	Residue
D	ASP532
D	TYR538
D	VAL539
D	TYR593
D	VAL597
D	HOH841
D	HOH908

---

site_id	AD6
Number of Residues	10
Details	binding site for residue EDO D 703

Chain	Residue
D	PHE10
D	LEU11
D	ASP14
D	ARG271
D	TRP276
D	TYR278
D	PRO279
D	ALA280
D	PHE281
D	GLU282

---

site_id	AD7
Number of Residues	3
Details	binding site for residue CA D 704

Chain	Residue
D	ASP152
D	ASN182
D	HOH924

---

site_id	AD8
Number of Residues	3
Details	binding site for residue CA D 705

Chain	Residue
C	HOH1086
D	GLU633
C	HOH1020

---

site_id	AD9
Number of Residues	5
Details	binding site for residue CA D 706

Chain	Residue
D	SER390
D	EDO701
D	HOH1031
D	HOH1057
D	HOH1151

---

Functional Information from PROSITE/UniProt

site_id	PS00801
Number of Residues	21
Details	TRANSKETOLASE_1 Transketolase signature 1. RflsADavqkanSGHPGapMG

Chain	Residue	Details
A	ARG9-GLY29

---

site_id	PS00802
Number of Residues	17
Details	TRANSKETOLASE_2 Transketolase signature 2. GEDGPTHqPIEqtAtlR

Chain	Residue	Details
A	GLY464-ARG480

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