5VPF
Transcription factor FosB/JunD bZIP domain in complex with cognate DNA, type-II crystal
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003700 | molecular_function | DNA-binding transcription factor activity |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| A | 0006357 | biological_process | regulation of transcription by RNA polymerase II |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003700 | molecular_function | DNA-binding transcription factor activity |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
| C | 0003677 | molecular_function | DNA binding |
| C | 0003700 | molecular_function | DNA-binding transcription factor activity |
| C | 0006355 | biological_process | regulation of DNA-templated transcription |
| C | 0006357 | biological_process | regulation of transcription by RNA polymerase II |
| D | 0003677 | molecular_function | DNA binding |
| D | 0003700 | molecular_function | DNA-binding transcription factor activity |
| D | 0006355 | biological_process | regulation of DNA-templated transcription |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 301 |
| Chain | Residue |
| A | ARG173 |
| B | ARG286 |
| F | DA9 |
| F | EDO101 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 302 |
| Chain | Residue |
| A | GLU191 |
| A | LYS194 |
| B | LYS299 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 303 |
| Chain | Residue |
| A | GLN184 |
| A | ASP188 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue CL A 304 |
| Chain | Residue |
| A | ARG161 |
| A | ARG164 |
| E | DC4 |
| E | DG5 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 401 |
| Chain | Residue |
| A | GLU212 |
| B | ARG279 |
| B | SER283 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue CL B 402 |
| Chain | Residue |
| B | ASN278 |
| B | ALA281 |
| F | DG5 |
| F | DG6 |
| F | HOH208 |
| site_id | AC7 |
| Number of Residues | 1 |
| Details | binding site for residue NA B 403 |
| Chain | Residue |
| B | SER283 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | binding site for residue EDO E 101 |
| Chain | Residue |
| E | DA17 |
| E | DC18 |
| site_id | AC9 |
| Number of Residues | 9 |
| Details | binding site for residue EDO F 101 |
| Chain | Residue |
| A | EDO301 |
| B | ALA282 |
| B | CYS285 |
| B | ARG286 |
| B | LYS289 |
| E | DT11 |
| F | DT7 |
| F | DG8 |
| F | DA9 |
| site_id | AD1 |
| Number of Residues | 4 |
| Details | binding site for residue EDO C 301 |
| Chain | Residue |
| C | ARG173 |
| D | ARG286 |
| H | DG8 |
| H | DA9 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for residue PO4 C 302 |
| Chain | Residue |
| C | GLN184 |
| C | ASP188 |
| C | GLU191 |
| D | LEU296 |
| D | LYS299 |
| site_id | AD3 |
| Number of Residues | 4 |
| Details | binding site for residue EDO D 401 |
| Chain | Residue |
| D | SER283 |
| D | ARG286 |
| G | DA9 |
| G | DC10 |
| site_id | AD4 |
| Number of Residues | 3 |
| Details | binding site for residue PO4 G 101 |
| Chain | Residue |
| G | DG16 |
| G | DA17 |
| G | DC18 |
Functional Information from PROSITE/UniProt
| site_id | PS00036 |
| Number of Residues | 15 |
| Details | BZIP_BASIC Basic-leucine zipper (bZIP) domain signature. Rre.RNKlAAAKcRNR |
| Chain | Residue | Details |
| A | ARG161-ARG175 | |
| B | ARG273-ARG288 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 189 |
| Details | Domain: {"description":"bZIP","evidences":[{"source":"PROSITE-ProRule","id":"PRU00978","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 104 |
| Details | Region: {"description":"Basic motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU00978","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 112 |
| Details | Region: {"description":"Leucine-zipper","evidences":[{"source":"PROSITE-ProRule","id":"PRU00978","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
