5VNA
Crystal structure of human YEATS domain
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 201 |
| Chain | Residue |
| A | THR48 |
| A | TYR50 |
| A | LYS52 |
| A | GLU87 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 201 |
| Chain | Residue |
| B | HIS43 |
| B | SER73 |
| B | TYR74 |
| B | HOH366 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 202 |
| Chain | Residue |
| B | GLY42 |
| B | HOH338 |
| B | LYS37 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 203 |
| Chain | Residue |
| B | TYR33 |
| B | EDO204 |
| B | HOH304 |
| B | HOH312 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | binding site for residue EDO B 204 |
| Chain | Residue |
| B | EDO203 |
| B | HOH318 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | binding site for residue EDO B 205 |
| Chain | Residue |
| B | HOH339 |
| B | HOH384 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 206 |
| Chain | Residue |
| B | GLY94 |
| B | GLU95 |
| B | PHE121 |
| B | HOH375 |
| D | NHE202 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 B 207 |
| Chain | Residue |
| A | LYS131 |
| A | HOH303 |
| B | LYS131 |
| B | LYS132 |
| B | THR133 |
| B | HOH332 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 B 208 |
| Chain | Residue |
| B | TYR50 |
| B | LYS52 |
| B | GLU87 |
| B | HOH313 |
| B | HOH316 |
| site_id | AD1 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 C 201 |
| Chain | Residue |
| C | VAL80 |
| C | VAL81 |
| C | THR82 |
| C | LYS83 |
| site_id | AD2 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 C 202 |
| Chain | Residue |
| B | ASN126 |
| B | LYS131 |
| C | HOH334 |
| site_id | AD3 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 D 201 |
| Chain | Residue |
| B | ARG32 |
| B | PHE34 |
| D | ARG32 |
| D | LYS131 |
| D | LYS132 |
| D | THR133 |
| D | HOH324 |
| site_id | AD4 |
| Number of Residues | 11 |
| Details | binding site for residue NHE D 202 |
| Chain | Residue |
| A | ARG15 |
| B | HIS71 |
| B | TRP93 |
| B | GLY94 |
| B | GLU95 |
| B | PHE96 |
| B | EDO206 |
| D | GLU97 |
| D | TYR115 |
| D | HOH302 |
| D | HOH309 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 16 |
| Details | Region: {"description":"Diacetylated histone H3 binding","evidences":[{"source":"PubMed","id":"29900004","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30071723","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5VNB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5XTZ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Site: {"description":"Interacts with diacetylated histone H3","evidences":[{"source":"PubMed","id":"29900004","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30071723","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5VNB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5XTZ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
