Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0016491 | molecular_function | oxidoreductase activity |
B | 0016491 | molecular_function | oxidoreductase activity |
C | 0016491 | molecular_function | oxidoreductase activity |
D | 0016491 | molecular_function | oxidoreductase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 32 |
Details | binding site for residue NAD A 301 |
Chain | Residue |
A | GLY12 |
A | LEU61 |
A | ASN87 |
A | ALA88 |
A | GLY89 |
A | ILE143 |
A | SER144 |
A | SER145 |
A | TYR158 |
A | LYS162 |
A | PRO188 |
A | ARG14 |
A | GLY189 |
A | ILE191 |
A | THR193 |
A | MET195 |
A | THR196 |
A | ACT302 |
A | HOH415 |
A | HOH423 |
A | HOH428 |
A | HOH463 |
A | ARG15 |
A | HOH467 |
A | HOH492 |
A | HOH548 |
A | GLY16 |
A | ILE17 |
A | ASP36 |
A | ARG37 |
A | SER59 |
A | ASP60 |
site_id | AC2 |
Number of Residues | 8 |
Details | binding site for residue ACT A 302 |
Chain | Residue |
A | SER145 |
A | SER147 |
A | ARG155 |
A | TYR158 |
A | GLY189 |
A | NAD301 |
A | HOH416 |
A | HOH513 |
site_id | AC3 |
Number of Residues | 5 |
Details | binding site for residue EDO A 303 |
Chain | Residue |
A | GLU41 |
A | ARG48 |
A | ALA55 |
A | PHE56 |
B | ARG5 |
site_id | AC4 |
Number of Residues | 31 |
Details | binding site for residue NAD B 301 |
Chain | Residue |
B | GLY12 |
B | ARG14 |
B | ARG15 |
B | GLY16 |
B | ILE17 |
B | ASP36 |
B | ARG37 |
B | SER59 |
B | ASP60 |
B | LEU61 |
B | ASN87 |
B | GLY89 |
B | VAL112 |
B | ILE143 |
B | SER144 |
B | SER145 |
B | TYR158 |
B | LYS162 |
B | PRO188 |
B | GLY189 |
B | ILE191 |
B | THR193 |
B | MET195 |
B | THR196 |
B | ACT302 |
B | HOH409 |
B | HOH435 |
B | HOH456 |
B | HOH469 |
B | HOH481 |
B | HOH515 |
site_id | AC5 |
Number of Residues | 8 |
Details | binding site for residue ACT B 302 |
Chain | Residue |
B | SER145 |
B | SER147 |
B | ARG155 |
B | TYR158 |
B | GLY189 |
B | NAD301 |
B | HOH411 |
B | HOH504 |
site_id | AC6 |
Number of Residues | 29 |
Details | binding site for residue NAD C 301 |
Chain | Residue |
C | TYR158 |
C | LYS162 |
C | PRO188 |
C | GLY189 |
C | ILE191 |
C | THR193 |
C | MET195 |
C | THR196 |
C | ACT302 |
C | HOH403 |
C | HOH417 |
C | HOH429 |
C | HOH484 |
C | HOH533 |
C | GLY12 |
C | ARG14 |
C | ARG15 |
C | GLY16 |
C | ILE17 |
C | ASP36 |
C | SER59 |
C | ASP60 |
C | LEU61 |
C | ASN87 |
C | ALA88 |
C | GLY89 |
C | ILE143 |
C | SER144 |
C | SER145 |
site_id | AC7 |
Number of Residues | 7 |
Details | binding site for residue ACT C 302 |
Chain | Residue |
C | SER145 |
C | SER147 |
C | ARG155 |
C | TYR158 |
C | GLY189 |
C | NAD301 |
C | HOH405 |
site_id | AC8 |
Number of Residues | 29 |
Details | binding site for residue NAD D 301 |
Chain | Residue |
D | GLY12 |
D | ARG14 |
D | ARG15 |
D | GLY16 |
D | ILE17 |
D | ASP36 |
D | ARG37 |
D | SER59 |
D | ASP60 |
D | LEU61 |
D | ASN87 |
D | GLY89 |
D | ILE143 |
D | SER144 |
D | SER145 |
D | TYR158 |
D | LYS162 |
D | PRO188 |
D | GLY189 |
D | ILE191 |
D | THR193 |
D | ASP194 |
D | MET195 |
D | THR196 |
D | ACT302 |
D | HOH421 |
D | HOH422 |
D | HOH445 |
D | HOH462 |
site_id | AC9 |
Number of Residues | 8 |
Details | binding site for residue ACT D 302 |
Chain | Residue |
D | SER145 |
D | SER147 |
D | ARG155 |
D | TYR158 |
D | GLY189 |
D | NAD301 |
D | HOH408 |
D | HOH522 |
Functional Information from PROSITE/UniProt
site_id | PS00061 |
Number of Residues | 29 |
Details | ADH_SHORT Short-chain dehydrogenases/reductases family signature. SvssvmtspeRldYCISKAGLtAFVqGLA |
Chain | Residue | Details |
A | SER145-ALA173 | |