5VJ2

Structure of human respiratory syncytial virus non-structural protein 1 (NS1)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0039504	biological_process	symbiont-mediated suppression of host adaptive immune response
A	0039540	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of RIG-I activity
A	0039545	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity
A	0039722	biological_process	symbiont-mediated suppression of host toll-like receptor signaling pathway
A	0039723	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity
A	0042025	cellular_component	host cell nucleus
B	0039504	biological_process	symbiont-mediated suppression of host adaptive immune response
B	0039540	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of RIG-I activity
B	0039545	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity
B	0039722	biological_process	symbiont-mediated suppression of host toll-like receptor signaling pathway
B	0039723	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity
B	0042025	cellular_component	host cell nucleus

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue DIO A 201

Chain	Residue
A	GLY87
A	ILE89
A	TYR125
A	DIO202
B	HIS47
B	GLY87

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site_id	AC2
Number of Residues	5
Details	binding site for residue DIO A 202

Chain	Residue
B	ILE89
B	TYR125
A	HIS47
A	GLY87
A	DIO201

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site_id	AC3
Number of Residues	3
Details	binding site for residue DIO A 203

Chain	Residue
A	THR121
A	TYR125
B	ILE60

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site_id	AC4
Number of Residues	6
Details	binding site for residue DIO A 204

Chain	Residue
A	PHE56
A	HIS58
B	TYR125
B	GLN128
B	LEU129
B	GOL204

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site_id	AC5
Number of Residues	2
Details	binding site for residue CL A 205

Chain	Residue
A	LYS43
A	SER63

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site_id	AC6
Number of Residues	4
Details	binding site for residue GOL A 207

Chain	Residue
A	MET92
B	HIS97
B	CYS98
B	SER99

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site_id	AC7
Number of Residues	5
Details	binding site for residue DIO B 201

Chain	Residue
A	ILE60
B	THR121
B	MET122
B	TYR125
B	GOL204

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site_id	AC8
Number of Residues	4
Details	binding site for residue CL B 203

Chain	Residue
B	LEU51
B	ASN52
B	ILE54
B	MET80

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site_id	AC9
Number of Residues	9
Details	binding site for residue GOL B 204

Chain	Residue
A	LYS112
A	SER114
A	DIO204
B	THR121
B	ASN124
B	TYR125
B	GLN128
B	DIO201
B	HOH324

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