5VHC
DHX36 with an N-terminal truncation bound to ADP-BeF3
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue MG D 1101 |
| Chain | Residue |
| D | THR239 |
| D | GLU337 |
| D | BEF1102 |
| D | ADP1103 |
| site_id | AC2 |
| Number of Residues | 11 |
| Details | binding site for residue BEF D 1102 |
| Chain | Residue |
| D | SER559 |
| D | ARG604 |
| D | ARG607 |
| D | MG1101 |
| D | ADP1103 |
| D | HOH1260 |
| D | THR234 |
| D | GLY235 |
| D | LYS238 |
| D | GLU337 |
| D | ALA369 |
| site_id | AC3 |
| Number of Residues | 19 |
| Details | binding site for residue ADP D 1103 |
| Chain | Residue |
| D | GLU233 |
| D | GLY235 |
| D | CYS236 |
| D | GLY237 |
| D | LYS238 |
| D | THR239 |
| D | THR240 |
| D | ARG277 |
| D | THR561 |
| D | ASP563 |
| D | ARG607 |
| D | VAL608 |
| D | MG1101 |
| D | BEF1102 |
| D | HOH1209 |
| D | HOH1234 |
| D | HOH1248 |
| D | HOH1259 |
| D | HOH1261 |
Functional Information from PROSITE/UniProt
| site_id | PS00690 |
| Number of Residues | 10 |
| Details | DEAH_ATP_HELICASE DEAH-box subfamily ATP-dependent helicases signature. ShIVLDEIHE |
| Chain | Residue | Details |
| D | SER331-GLU340 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 170 |
| Details | Domain: {"description":"Helicase ATP-binding","evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 170 |
| Details | Domain: {"description":"Helicase C-terminal","evidences":[{"source":"PROSITE-ProRule","id":"PRU00542","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 200 |
| Details | Region: {"description":"Necessary for interaction with single-stranded DNA at the 3'-end of the G4-DNA structure","evidences":[{"source":"PubMed","id":"29899445","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 69 |
| Details | Region: {"description":"WH domain","evidences":[{"source":"PubMed","id":"29899445","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 3 |
| Details | Motif: {"description":"DEAH box","evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 11 |
| Details | Motif: {"description":"Nuclear localization signal","evidences":[{"source":"UniProtKB","id":"Q9H2U1","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"29899445","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5VHC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5VHD","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"29899445","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5VHC","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"29899445","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5VHD","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"Q9H2U1","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"Q9H2U1","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
