5VFO

Nucleotide-driven Triple-state Remodeling of the AAA-ATPase Channel in the Activated Human 26S Proteasome

Functional Information from GO Data

Chain	GOid	namespace	contents
G	0000502	cellular_component	proteasome complex
G	0000932	cellular_component	P-body
G	0002376	biological_process	immune system process
G	0003723	molecular_function	RNA binding
G	0004175	molecular_function	endopeptidase activity
G	0005515	molecular_function	protein binding
G	0005634	cellular_component	nucleus
G	0005654	cellular_component	nucleoplasm
G	0005737	cellular_component	cytoplasm
G	0005829	cellular_component	cytosol
G	0005839	cellular_component	proteasome core complex
G	0005840	cellular_component	ribosome
G	0006281	biological_process	DNA repair
G	0006511	biological_process	ubiquitin-dependent protein catabolic process
G	0006915	biological_process	apoptotic process
G	0006974	biological_process	DNA damage response
G	0006979	biological_process	response to oxidative stress
G	0007283	biological_process	spermatogenesis
G	0008021	cellular_component	synaptic vesicle
G	0010498	biological_process	proteasomal protein catabolic process
G	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
G	0016363	cellular_component	nuclear matrix
G	0019773	cellular_component	proteasome core complex, alpha-subunit complex
G	0030016	cellular_component	myofibril
G	0030017	cellular_component	sarcomere
G	0030317	biological_process	flagellated sperm motility
G	0032729	biological_process	positive regulation of type II interferon production
G	0032743	biological_process	positive regulation of interleukin-2 production
G	0032760	biological_process	positive regulation of tumor necrosis factor production
G	0034341	biological_process	response to type II interferon
G	0034515	cellular_component	proteasome storage granule
G	0035639	molecular_function	purine ribonucleoside triphosphate binding
G	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
G	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
G	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
G	0045061	biological_process	thymic T cell selection
G	0045063	biological_process	T-helper 1 cell differentiation
G	0045590	biological_process	negative regulation of regulatory T cell differentiation
G	0050727	biological_process	regulation of inflammatory response
G	0051059	molecular_function	NF-kappaB binding
G	0051321	biological_process	meiotic cell cycle
G	0051603	biological_process	proteolysis involved in protein catabolic process
G	0061136	biological_process	regulation of proteasomal protein catabolic process
G	0070062	cellular_component	extracellular exosome
G	0071357	biological_process	cellular response to type I interferon
G	0072539	biological_process	T-helper 17 cell differentiation
G	0097229	cellular_component	sperm end piece
G	0097542	cellular_component	ciliary tip
G	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
G	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
H	0000502	cellular_component	proteasome complex
H	0000932	cellular_component	P-body
H	0002376	biological_process	immune system process
H	0005515	molecular_function	protein binding
H	0005576	cellular_component	extracellular region
H	0005634	cellular_component	nucleus
H	0005654	cellular_component	nucleoplasm
H	0005737	cellular_component	cytoplasm
H	0005829	cellular_component	cytosol
H	0005839	cellular_component	proteasome core complex
H	0006281	biological_process	DNA repair
H	0006511	biological_process	ubiquitin-dependent protein catabolic process
H	0006915	biological_process	apoptotic process
H	0006974	biological_process	DNA damage response
H	0006979	biological_process	response to oxidative stress
H	0007283	biological_process	spermatogenesis
H	0008021	cellular_component	synaptic vesicle
H	0009615	biological_process	response to virus
H	0010498	biological_process	proteasomal protein catabolic process
H	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
H	0019773	cellular_component	proteasome core complex, alpha-subunit complex
H	0030317	biological_process	flagellated sperm motility
H	0032729	biological_process	positive regulation of type II interferon production
H	0032743	biological_process	positive regulation of interleukin-2 production
H	0032760	biological_process	positive regulation of tumor necrosis factor production
H	0034341	biological_process	response to type II interferon
H	0034515	cellular_component	proteasome storage granule
H	0034774	cellular_component	secretory granule lumen
H	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
H	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
H	0045061	biological_process	thymic T cell selection
H	0045063	biological_process	T-helper 1 cell differentiation
H	0045590	biological_process	negative regulation of regulatory T cell differentiation
H	0051321	biological_process	meiotic cell cycle
H	0051603	biological_process	proteolysis involved in protein catabolic process
H	0061136	biological_process	regulation of proteasomal protein catabolic process
H	0070062	cellular_component	extracellular exosome
H	0071357	biological_process	cellular response to type I interferon
H	0072539	biological_process	T-helper 17 cell differentiation
H	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
H	1904813	cellular_component	ficolin-1-rich granule lumen
H	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
I	0000502	cellular_component	proteasome complex
I	0000932	cellular_component	P-body
I	0002376	biological_process	immune system process
I	0005515	molecular_function	protein binding
I	0005634	cellular_component	nucleus
I	0005654	cellular_component	nucleoplasm
I	0005737	cellular_component	cytoplasm
I	0005829	cellular_component	cytosol
I	0005839	cellular_component	proteasome core complex
I	0006281	biological_process	DNA repair
I	0006511	biological_process	ubiquitin-dependent protein catabolic process
I	0006915	biological_process	apoptotic process
I	0006974	biological_process	DNA damage response
I	0006979	biological_process	response to oxidative stress
I	0007283	biological_process	spermatogenesis
I	0008021	cellular_component	synaptic vesicle
I	0010498	biological_process	proteasomal protein catabolic process
I	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
I	0019773	cellular_component	proteasome core complex, alpha-subunit complex
I	0030317	biological_process	flagellated sperm motility
I	0032729	biological_process	positive regulation of type II interferon production
I	0032743	biological_process	positive regulation of interleukin-2 production
I	0032760	biological_process	positive regulation of tumor necrosis factor production
I	0034341	biological_process	response to type II interferon
I	0034515	cellular_component	proteasome storage granule
I	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
I	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
I	0045061	biological_process	thymic T cell selection
I	0045063	biological_process	T-helper 1 cell differentiation
I	0045590	biological_process	negative regulation of regulatory T cell differentiation
I	0051321	biological_process	meiotic cell cycle
I	0051603	biological_process	proteolysis involved in protein catabolic process
I	0061136	biological_process	regulation of proteasomal protein catabolic process
I	0070062	cellular_component	extracellular exosome
I	0071357	biological_process	cellular response to type I interferon
I	0072539	biological_process	T-helper 17 cell differentiation
I	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
I	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
J	0000502	cellular_component	proteasome complex
J	0002376	biological_process	immune system process
J	0005515	molecular_function	protein binding
J	0005634	cellular_component	nucleus
J	0005654	cellular_component	nucleoplasm
J	0005737	cellular_component	cytoplasm
J	0005829	cellular_component	cytosol
J	0005839	cellular_component	proteasome core complex
J	0006281	biological_process	DNA repair
J	0006511	biological_process	ubiquitin-dependent protein catabolic process
J	0006915	biological_process	apoptotic process
J	0006974	biological_process	DNA damage response
J	0006979	biological_process	response to oxidative stress
J	0008021	cellular_component	synaptic vesicle
J	0010498	biological_process	proteasomal protein catabolic process
J	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
J	0019773	cellular_component	proteasome core complex, alpha-subunit complex
J	0030317	biological_process	flagellated sperm motility
J	0032729	biological_process	positive regulation of type II interferon production
J	0032743	biological_process	positive regulation of interleukin-2 production
J	0032760	biological_process	positive regulation of tumor necrosis factor production
J	0034341	biological_process	response to type II interferon
J	0034515	cellular_component	proteasome storage granule
J	0042802	molecular_function	identical protein binding
J	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
J	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
J	0045061	biological_process	thymic T cell selection
J	0045063	biological_process	T-helper 1 cell differentiation
J	0045590	biological_process	negative regulation of regulatory T cell differentiation
J	0051603	biological_process	proteolysis involved in protein catabolic process
J	0061136	biological_process	regulation of proteasomal protein catabolic process
J	0070062	cellular_component	extracellular exosome
J	0071357	biological_process	cellular response to type I interferon
J	0072539	biological_process	T-helper 17 cell differentiation
J	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
J	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
K	0000502	cellular_component	proteasome complex
K	0002376	biological_process	immune system process
K	0005515	molecular_function	protein binding
K	0005576	cellular_component	extracellular region
K	0005634	cellular_component	nucleus
K	0005654	cellular_component	nucleoplasm
K	0005737	cellular_component	cytoplasm
K	0005829	cellular_component	cytosol
K	0005839	cellular_component	proteasome core complex
K	0006281	biological_process	DNA repair
K	0006511	biological_process	ubiquitin-dependent protein catabolic process
K	0006915	biological_process	apoptotic process
K	0006974	biological_process	DNA damage response
K	0006979	biological_process	response to oxidative stress
K	0007283	biological_process	spermatogenesis
K	0008021	cellular_component	synaptic vesicle
K	0010498	biological_process	proteasomal protein catabolic process
K	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
K	0019773	cellular_component	proteasome core complex, alpha-subunit complex
K	0030317	biological_process	flagellated sperm motility
K	0032729	biological_process	positive regulation of type II interferon production
K	0032743	biological_process	positive regulation of interleukin-2 production
K	0032760	biological_process	positive regulation of tumor necrosis factor production
K	0034341	biological_process	response to type II interferon
K	0034515	cellular_component	proteasome storage granule
K	0034774	cellular_component	secretory granule lumen
K	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
K	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
K	0045061	biological_process	thymic T cell selection
K	0045063	biological_process	T-helper 1 cell differentiation
K	0045590	biological_process	negative regulation of regulatory T cell differentiation
K	0051321	biological_process	meiotic cell cycle
K	0051603	biological_process	proteolysis involved in protein catabolic process
K	0061136	biological_process	regulation of proteasomal protein catabolic process
K	0070062	cellular_component	extracellular exosome
K	0071357	biological_process	cellular response to type I interferon
K	0072539	biological_process	T-helper 17 cell differentiation
K	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
K	1904813	cellular_component	ficolin-1-rich granule lumen
K	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
L	0000502	cellular_component	proteasome complex
L	0001530	molecular_function	lipopolysaccharide binding
L	0002376	biological_process	immune system process
L	0002862	biological_process	negative regulation of inflammatory response to antigenic stimulus
L	0005515	molecular_function	protein binding
L	0005634	cellular_component	nucleus
L	0005654	cellular_component	nucleoplasm
L	0005737	cellular_component	cytoplasm
L	0005829	cellular_component	cytosol
L	0005839	cellular_component	proteasome core complex
L	0006281	biological_process	DNA repair
L	0006511	biological_process	ubiquitin-dependent protein catabolic process
L	0006915	biological_process	apoptotic process
L	0006974	biological_process	DNA damage response
L	0006979	biological_process	response to oxidative stress
L	0007283	biological_process	spermatogenesis
L	0008021	cellular_component	synaptic vesicle
L	0010498	biological_process	proteasomal protein catabolic process
L	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
L	0016604	cellular_component	nuclear body
L	0019773	cellular_component	proteasome core complex, alpha-subunit complex
L	0030317	biological_process	flagellated sperm motility
L	0032729	biological_process	positive regulation of type II interferon production
L	0032743	biological_process	positive regulation of interleukin-2 production
L	0032760	biological_process	positive regulation of tumor necrosis factor production
L	0034341	biological_process	response to type II interferon
L	0034515	cellular_component	proteasome storage granule
L	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
L	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
L	0045061	biological_process	thymic T cell selection
L	0045063	biological_process	T-helper 1 cell differentiation
L	0045590	biological_process	negative regulation of regulatory T cell differentiation
L	0051321	biological_process	meiotic cell cycle
L	0051603	biological_process	proteolysis involved in protein catabolic process
L	0061136	biological_process	regulation of proteasomal protein catabolic process
L	0070062	cellular_component	extracellular exosome
L	0071357	biological_process	cellular response to type I interferon
L	0072539	biological_process	T-helper 17 cell differentiation
L	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
L	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
M	0000502	cellular_component	proteasome complex
M	0002376	biological_process	immune system process
M	0005515	molecular_function	protein binding
M	0005634	cellular_component	nucleus
M	0005654	cellular_component	nucleoplasm
M	0005737	cellular_component	cytoplasm
M	0005829	cellular_component	cytosol
M	0005839	cellular_component	proteasome core complex
M	0006281	biological_process	DNA repair
M	0006511	biological_process	ubiquitin-dependent protein catabolic process
M	0006915	biological_process	apoptotic process
M	0006974	biological_process	DNA damage response
M	0006979	biological_process	response to oxidative stress
M	0007283	biological_process	spermatogenesis
M	0008021	cellular_component	synaptic vesicle
M	0010498	biological_process	proteasomal protein catabolic process
M	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
M	0019773	cellular_component	proteasome core complex, alpha-subunit complex
M	0030317	biological_process	flagellated sperm motility
M	0031625	molecular_function	ubiquitin protein ligase binding
M	0032729	biological_process	positive regulation of type II interferon production
M	0032743	biological_process	positive regulation of interleukin-2 production
M	0032760	biological_process	positive regulation of tumor necrosis factor production
M	0034341	biological_process	response to type II interferon
M	0034515	cellular_component	proteasome storage granule
M	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
M	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
M	0045061	biological_process	thymic T cell selection
M	0045063	biological_process	T-helper 1 cell differentiation
M	0045590	biological_process	negative regulation of regulatory T cell differentiation
M	0051321	biological_process	meiotic cell cycle
M	0051603	biological_process	proteolysis involved in protein catabolic process
M	0061136	biological_process	regulation of proteasomal protein catabolic process
M	0070062	cellular_component	extracellular exosome
M	0071357	biological_process	cellular response to type I interferon
M	0072539	biological_process	T-helper 17 cell differentiation
M	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
M	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
N	0004298	molecular_function	threonine-type endopeptidase activity
N	0005839	cellular_component	proteasome core complex
N	0051603	biological_process	proteolysis involved in protein catabolic process
O	0004298	molecular_function	threonine-type endopeptidase activity
O	0005839	cellular_component	proteasome core complex
O	0051603	biological_process	proteolysis involved in protein catabolic process
P	0000502	cellular_component	proteasome complex
P	0002376	biological_process	immune system process
P	0005515	molecular_function	protein binding
P	0005634	cellular_component	nucleus
P	0005654	cellular_component	nucleoplasm
P	0005737	cellular_component	cytoplasm
P	0005829	cellular_component	cytosol
P	0005839	cellular_component	proteasome core complex
P	0006281	biological_process	DNA repair
P	0006915	biological_process	apoptotic process
P	0006974	biological_process	DNA damage response
P	0006979	biological_process	response to oxidative stress
P	0007283	biological_process	spermatogenesis
P	0008021	cellular_component	synaptic vesicle
P	0010498	biological_process	proteasomal protein catabolic process
P	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
P	0019774	cellular_component	proteasome core complex, beta-subunit complex
P	0030317	biological_process	flagellated sperm motility
P	0032729	biological_process	positive regulation of type II interferon production
P	0032743	biological_process	positive regulation of interleukin-2 production
P	0032760	biological_process	positive regulation of tumor necrosis factor production
P	0034341	biological_process	response to type II interferon
P	0034515	cellular_component	proteasome storage granule
P	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
P	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
P	0045061	biological_process	thymic T cell selection
P	0045063	biological_process	T-helper 1 cell differentiation
P	0045590	biological_process	negative regulation of regulatory T cell differentiation
P	0051321	biological_process	meiotic cell cycle
P	0051603	biological_process	proteolysis involved in protein catabolic process
P	0061136	biological_process	regulation of proteasomal protein catabolic process
P	0070062	cellular_component	extracellular exosome
P	0071357	biological_process	cellular response to type I interferon
P	0072539	biological_process	T-helper 17 cell differentiation
P	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
P	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
Q	0000502	cellular_component	proteasome complex
Q	0002376	biological_process	immune system process
Q	0005515	molecular_function	protein binding
Q	0005634	cellular_component	nucleus
Q	0005654	cellular_component	nucleoplasm
Q	0005737	cellular_component	cytoplasm
Q	0005829	cellular_component	cytosol
Q	0005839	cellular_component	proteasome core complex
Q	0006281	biological_process	DNA repair
Q	0006915	biological_process	apoptotic process
Q	0006974	biological_process	DNA damage response
Q	0006979	biological_process	response to oxidative stress
Q	0007283	biological_process	spermatogenesis
Q	0008021	cellular_component	synaptic vesicle
Q	0010498	biological_process	proteasomal protein catabolic process
Q	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
Q	0016020	cellular_component	membrane
Q	0019774	cellular_component	proteasome core complex, beta-subunit complex
Q	0030317	biological_process	flagellated sperm motility
Q	0032729	biological_process	positive regulation of type II interferon production
Q	0032743	biological_process	positive regulation of interleukin-2 production
Q	0032760	biological_process	positive regulation of tumor necrosis factor production
Q	0034341	biological_process	response to type II interferon
Q	0034515	cellular_component	proteasome storage granule
Q	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
Q	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
Q	0045061	biological_process	thymic T cell selection
Q	0045063	biological_process	T-helper 1 cell differentiation
Q	0045590	biological_process	negative regulation of regulatory T cell differentiation
Q	0051321	biological_process	meiotic cell cycle
Q	0051603	biological_process	proteolysis involved in protein catabolic process
Q	0061136	biological_process	regulation of proteasomal protein catabolic process
Q	0070062	cellular_component	extracellular exosome
Q	0071357	biological_process	cellular response to type I interferon
Q	0072539	biological_process	T-helper 17 cell differentiation
Q	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
Q	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
R	0004298	molecular_function	threonine-type endopeptidase activity
R	0005839	cellular_component	proteasome core complex
R	0051603	biological_process	proteolysis involved in protein catabolic process
S	0005839	cellular_component	proteasome core complex
S	0051603	biological_process	proteolysis involved in protein catabolic process
T	0005839	cellular_component	proteasome core complex
T	0051603	biological_process	proteolysis involved in protein catabolic process
g	0000502	cellular_component	proteasome complex
g	0000932	cellular_component	P-body
g	0002376	biological_process	immune system process
g	0003723	molecular_function	RNA binding
g	0004175	molecular_function	endopeptidase activity
g	0005515	molecular_function	protein binding
g	0005634	cellular_component	nucleus
g	0005654	cellular_component	nucleoplasm
g	0005737	cellular_component	cytoplasm
g	0005829	cellular_component	cytosol
g	0005839	cellular_component	proteasome core complex
g	0005840	cellular_component	ribosome
g	0006281	biological_process	DNA repair
g	0006511	biological_process	ubiquitin-dependent protein catabolic process
g	0006915	biological_process	apoptotic process
g	0006974	biological_process	DNA damage response
g	0006979	biological_process	response to oxidative stress
g	0007283	biological_process	spermatogenesis
g	0008021	cellular_component	synaptic vesicle
g	0010498	biological_process	proteasomal protein catabolic process
g	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
g	0016363	cellular_component	nuclear matrix
g	0019773	cellular_component	proteasome core complex, alpha-subunit complex
g	0030016	cellular_component	myofibril
g	0030017	cellular_component	sarcomere
g	0030317	biological_process	flagellated sperm motility
g	0032729	biological_process	positive regulation of type II interferon production
g	0032743	biological_process	positive regulation of interleukin-2 production
g	0032760	biological_process	positive regulation of tumor necrosis factor production
g	0034341	biological_process	response to type II interferon
g	0034515	cellular_component	proteasome storage granule
g	0035639	molecular_function	purine ribonucleoside triphosphate binding
g	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
g	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
g	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
g	0045061	biological_process	thymic T cell selection
g	0045063	biological_process	T-helper 1 cell differentiation
g	0045590	biological_process	negative regulation of regulatory T cell differentiation
g	0050727	biological_process	regulation of inflammatory response
g	0051059	molecular_function	NF-kappaB binding
g	0051321	biological_process	meiotic cell cycle
g	0051603	biological_process	proteolysis involved in protein catabolic process
g	0061136	biological_process	regulation of proteasomal protein catabolic process
g	0070062	cellular_component	extracellular exosome
g	0071357	biological_process	cellular response to type I interferon
g	0072539	biological_process	T-helper 17 cell differentiation
g	0097229	cellular_component	sperm end piece
g	0097542	cellular_component	ciliary tip
g	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
g	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
h	0000502	cellular_component	proteasome complex
h	0000932	cellular_component	P-body
h	0002376	biological_process	immune system process
h	0005515	molecular_function	protein binding
h	0005576	cellular_component	extracellular region
h	0005634	cellular_component	nucleus
h	0005654	cellular_component	nucleoplasm
h	0005737	cellular_component	cytoplasm
h	0005829	cellular_component	cytosol
h	0005839	cellular_component	proteasome core complex
h	0006281	biological_process	DNA repair
h	0006511	biological_process	ubiquitin-dependent protein catabolic process
h	0006915	biological_process	apoptotic process
h	0006974	biological_process	DNA damage response
h	0006979	biological_process	response to oxidative stress
h	0007283	biological_process	spermatogenesis
h	0008021	cellular_component	synaptic vesicle
h	0009615	biological_process	response to virus
h	0010498	biological_process	proteasomal protein catabolic process
h	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
h	0019773	cellular_component	proteasome core complex, alpha-subunit complex
h	0030317	biological_process	flagellated sperm motility
h	0032729	biological_process	positive regulation of type II interferon production
h	0032743	biological_process	positive regulation of interleukin-2 production
h	0032760	biological_process	positive regulation of tumor necrosis factor production
h	0034341	biological_process	response to type II interferon
h	0034515	cellular_component	proteasome storage granule
h	0034774	cellular_component	secretory granule lumen
h	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
h	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
h	0045061	biological_process	thymic T cell selection
h	0045063	biological_process	T-helper 1 cell differentiation
h	0045590	biological_process	negative regulation of regulatory T cell differentiation
h	0051321	biological_process	meiotic cell cycle
h	0051603	biological_process	proteolysis involved in protein catabolic process
h	0061136	biological_process	regulation of proteasomal protein catabolic process
h	0070062	cellular_component	extracellular exosome
h	0071357	biological_process	cellular response to type I interferon
h	0072539	biological_process	T-helper 17 cell differentiation
h	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
h	1904813	cellular_component	ficolin-1-rich granule lumen
h	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
i	0000502	cellular_component	proteasome complex
i	0000932	cellular_component	P-body
i	0002376	biological_process	immune system process
i	0005515	molecular_function	protein binding
i	0005634	cellular_component	nucleus
i	0005654	cellular_component	nucleoplasm
i	0005737	cellular_component	cytoplasm
i	0005829	cellular_component	cytosol
i	0005839	cellular_component	proteasome core complex
i	0006281	biological_process	DNA repair
i	0006511	biological_process	ubiquitin-dependent protein catabolic process
i	0006915	biological_process	apoptotic process
i	0006974	biological_process	DNA damage response
i	0006979	biological_process	response to oxidative stress
i	0007283	biological_process	spermatogenesis
i	0008021	cellular_component	synaptic vesicle
i	0010498	biological_process	proteasomal protein catabolic process
i	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
i	0019773	cellular_component	proteasome core complex, alpha-subunit complex
i	0030317	biological_process	flagellated sperm motility
i	0032729	biological_process	positive regulation of type II interferon production
i	0032743	biological_process	positive regulation of interleukin-2 production
i	0032760	biological_process	positive regulation of tumor necrosis factor production
i	0034341	biological_process	response to type II interferon
i	0034515	cellular_component	proteasome storage granule
i	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
i	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
i	0045061	biological_process	thymic T cell selection
i	0045063	biological_process	T-helper 1 cell differentiation
i	0045590	biological_process	negative regulation of regulatory T cell differentiation
i	0051321	biological_process	meiotic cell cycle
i	0051603	biological_process	proteolysis involved in protein catabolic process
i	0061136	biological_process	regulation of proteasomal protein catabolic process
i	0070062	cellular_component	extracellular exosome
i	0071357	biological_process	cellular response to type I interferon
i	0072539	biological_process	T-helper 17 cell differentiation
i	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
i	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
j	0000502	cellular_component	proteasome complex
j	0002376	biological_process	immune system process
j	0005515	molecular_function	protein binding
j	0005634	cellular_component	nucleus
j	0005654	cellular_component	nucleoplasm
j	0005737	cellular_component	cytoplasm
j	0005829	cellular_component	cytosol
j	0005839	cellular_component	proteasome core complex
j	0006281	biological_process	DNA repair
j	0006511	biological_process	ubiquitin-dependent protein catabolic process
j	0006915	biological_process	apoptotic process
j	0006974	biological_process	DNA damage response
j	0006979	biological_process	response to oxidative stress
j	0008021	cellular_component	synaptic vesicle
j	0010498	biological_process	proteasomal protein catabolic process
j	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
j	0019773	cellular_component	proteasome core complex, alpha-subunit complex
j	0030317	biological_process	flagellated sperm motility
j	0032729	biological_process	positive regulation of type II interferon production
j	0032743	biological_process	positive regulation of interleukin-2 production
j	0032760	biological_process	positive regulation of tumor necrosis factor production
j	0034341	biological_process	response to type II interferon
j	0034515	cellular_component	proteasome storage granule
j	0042802	molecular_function	identical protein binding
j	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
j	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
j	0045061	biological_process	thymic T cell selection
j	0045063	biological_process	T-helper 1 cell differentiation
j	0045590	biological_process	negative regulation of regulatory T cell differentiation
j	0051603	biological_process	proteolysis involved in protein catabolic process
j	0061136	biological_process	regulation of proteasomal protein catabolic process
j	0070062	cellular_component	extracellular exosome
j	0071357	biological_process	cellular response to type I interferon
j	0072539	biological_process	T-helper 17 cell differentiation
j	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
j	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
k	0000502	cellular_component	proteasome complex
k	0002376	biological_process	immune system process
k	0005515	molecular_function	protein binding
k	0005576	cellular_component	extracellular region
k	0005634	cellular_component	nucleus
k	0005654	cellular_component	nucleoplasm
k	0005737	cellular_component	cytoplasm
k	0005829	cellular_component	cytosol
k	0005839	cellular_component	proteasome core complex
k	0006281	biological_process	DNA repair
k	0006511	biological_process	ubiquitin-dependent protein catabolic process
k	0006915	biological_process	apoptotic process
k	0006974	biological_process	DNA damage response
k	0006979	biological_process	response to oxidative stress
k	0007283	biological_process	spermatogenesis
k	0008021	cellular_component	synaptic vesicle
k	0010498	biological_process	proteasomal protein catabolic process
k	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
k	0019773	cellular_component	proteasome core complex, alpha-subunit complex
k	0030317	biological_process	flagellated sperm motility
k	0032729	biological_process	positive regulation of type II interferon production
k	0032743	biological_process	positive regulation of interleukin-2 production
k	0032760	biological_process	positive regulation of tumor necrosis factor production
k	0034341	biological_process	response to type II interferon
k	0034515	cellular_component	proteasome storage granule
k	0034774	cellular_component	secretory granule lumen
k	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
k	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
k	0045061	biological_process	thymic T cell selection
k	0045063	biological_process	T-helper 1 cell differentiation
k	0045590	biological_process	negative regulation of regulatory T cell differentiation
k	0051321	biological_process	meiotic cell cycle
k	0051603	biological_process	proteolysis involved in protein catabolic process
k	0061136	biological_process	regulation of proteasomal protein catabolic process
k	0070062	cellular_component	extracellular exosome
k	0071357	biological_process	cellular response to type I interferon
k	0072539	biological_process	T-helper 17 cell differentiation
k	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
k	1904813	cellular_component	ficolin-1-rich granule lumen
k	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
l	0000502	cellular_component	proteasome complex
l	0001530	molecular_function	lipopolysaccharide binding
l	0002376	biological_process	immune system process
l	0002862	biological_process	negative regulation of inflammatory response to antigenic stimulus
l	0005515	molecular_function	protein binding
l	0005634	cellular_component	nucleus
l	0005654	cellular_component	nucleoplasm
l	0005737	cellular_component	cytoplasm
l	0005829	cellular_component	cytosol
l	0005839	cellular_component	proteasome core complex
l	0006281	biological_process	DNA repair
l	0006511	biological_process	ubiquitin-dependent protein catabolic process
l	0006915	biological_process	apoptotic process
l	0006974	biological_process	DNA damage response
l	0006979	biological_process	response to oxidative stress
l	0007283	biological_process	spermatogenesis
l	0008021	cellular_component	synaptic vesicle
l	0010498	biological_process	proteasomal protein catabolic process
l	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
l	0016604	cellular_component	nuclear body
l	0019773	cellular_component	proteasome core complex, alpha-subunit complex
l	0030317	biological_process	flagellated sperm motility
l	0032729	biological_process	positive regulation of type II interferon production
l	0032743	biological_process	positive regulation of interleukin-2 production
l	0032760	biological_process	positive regulation of tumor necrosis factor production
l	0034341	biological_process	response to type II interferon
l	0034515	cellular_component	proteasome storage granule
l	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
l	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
l	0045061	biological_process	thymic T cell selection
l	0045063	biological_process	T-helper 1 cell differentiation
l	0045590	biological_process	negative regulation of regulatory T cell differentiation
l	0051321	biological_process	meiotic cell cycle
l	0051603	biological_process	proteolysis involved in protein catabolic process
l	0061136	biological_process	regulation of proteasomal protein catabolic process
l	0070062	cellular_component	extracellular exosome
l	0071357	biological_process	cellular response to type I interferon
l	0072539	biological_process	T-helper 17 cell differentiation
l	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
l	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
m	0000502	cellular_component	proteasome complex
m	0002376	biological_process	immune system process
m	0005515	molecular_function	protein binding
m	0005634	cellular_component	nucleus
m	0005654	cellular_component	nucleoplasm
m	0005737	cellular_component	cytoplasm
m	0005829	cellular_component	cytosol
m	0005839	cellular_component	proteasome core complex
m	0006281	biological_process	DNA repair
m	0006511	biological_process	ubiquitin-dependent protein catabolic process
m	0006915	biological_process	apoptotic process
m	0006974	biological_process	DNA damage response
m	0006979	biological_process	response to oxidative stress
m	0007283	biological_process	spermatogenesis
m	0008021	cellular_component	synaptic vesicle
m	0010498	biological_process	proteasomal protein catabolic process
m	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
m	0019773	cellular_component	proteasome core complex, alpha-subunit complex
m	0030317	biological_process	flagellated sperm motility
m	0031625	molecular_function	ubiquitin protein ligase binding
m	0032729	biological_process	positive regulation of type II interferon production
m	0032743	biological_process	positive regulation of interleukin-2 production
m	0032760	biological_process	positive regulation of tumor necrosis factor production
m	0034341	biological_process	response to type II interferon
m	0034515	cellular_component	proteasome storage granule
m	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
m	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
m	0045061	biological_process	thymic T cell selection
m	0045063	biological_process	T-helper 1 cell differentiation
m	0045590	biological_process	negative regulation of regulatory T cell differentiation
m	0051321	biological_process	meiotic cell cycle
m	0051603	biological_process	proteolysis involved in protein catabolic process
m	0061136	biological_process	regulation of proteasomal protein catabolic process
m	0070062	cellular_component	extracellular exosome
m	0071357	biological_process	cellular response to type I interferon
m	0072539	biological_process	T-helper 17 cell differentiation
m	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
m	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
n	0004298	molecular_function	threonine-type endopeptidase activity
n	0005839	cellular_component	proteasome core complex
n	0051603	biological_process	proteolysis involved in protein catabolic process
o	0004298	molecular_function	threonine-type endopeptidase activity
o	0005839	cellular_component	proteasome core complex
o	0051603	biological_process	proteolysis involved in protein catabolic process
p	0000502	cellular_component	proteasome complex
p	0002376	biological_process	immune system process
p	0005515	molecular_function	protein binding
p	0005634	cellular_component	nucleus
p	0005654	cellular_component	nucleoplasm
p	0005737	cellular_component	cytoplasm
p	0005829	cellular_component	cytosol
p	0005839	cellular_component	proteasome core complex
p	0006281	biological_process	DNA repair
p	0006915	biological_process	apoptotic process
p	0006974	biological_process	DNA damage response
p	0006979	biological_process	response to oxidative stress
p	0007283	biological_process	spermatogenesis
p	0008021	cellular_component	synaptic vesicle
p	0010498	biological_process	proteasomal protein catabolic process
p	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
p	0019774	cellular_component	proteasome core complex, beta-subunit complex
p	0030317	biological_process	flagellated sperm motility
p	0032729	biological_process	positive regulation of type II interferon production
p	0032743	biological_process	positive regulation of interleukin-2 production
p	0032760	biological_process	positive regulation of tumor necrosis factor production
p	0034341	biological_process	response to type II interferon
p	0034515	cellular_component	proteasome storage granule
p	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
p	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
p	0045061	biological_process	thymic T cell selection
p	0045063	biological_process	T-helper 1 cell differentiation
p	0045590	biological_process	negative regulation of regulatory T cell differentiation
p	0051321	biological_process	meiotic cell cycle
p	0051603	biological_process	proteolysis involved in protein catabolic process
p	0061136	biological_process	regulation of proteasomal protein catabolic process
p	0070062	cellular_component	extracellular exosome
p	0071357	biological_process	cellular response to type I interferon
p	0072539	biological_process	T-helper 17 cell differentiation
p	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
p	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
q	0000502	cellular_component	proteasome complex
q	0002376	biological_process	immune system process
q	0005515	molecular_function	protein binding
q	0005634	cellular_component	nucleus
q	0005654	cellular_component	nucleoplasm
q	0005737	cellular_component	cytoplasm
q	0005829	cellular_component	cytosol
q	0005839	cellular_component	proteasome core complex
q	0006281	biological_process	DNA repair
q	0006915	biological_process	apoptotic process
q	0006974	biological_process	DNA damage response
q	0006979	biological_process	response to oxidative stress
q	0007283	biological_process	spermatogenesis
q	0008021	cellular_component	synaptic vesicle
q	0010498	biological_process	proteasomal protein catabolic process
q	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
q	0016020	cellular_component	membrane
q	0019774	cellular_component	proteasome core complex, beta-subunit complex
q	0030317	biological_process	flagellated sperm motility
q	0032729	biological_process	positive regulation of type II interferon production
q	0032743	biological_process	positive regulation of interleukin-2 production
q	0032760	biological_process	positive regulation of tumor necrosis factor production
q	0034341	biological_process	response to type II interferon
q	0034515	cellular_component	proteasome storage granule
q	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
q	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
q	0045061	biological_process	thymic T cell selection
q	0045063	biological_process	T-helper 1 cell differentiation
q	0045590	biological_process	negative regulation of regulatory T cell differentiation
q	0051321	biological_process	meiotic cell cycle
q	0051603	biological_process	proteolysis involved in protein catabolic process
q	0061136	biological_process	regulation of proteasomal protein catabolic process
q	0070062	cellular_component	extracellular exosome
q	0071357	biological_process	cellular response to type I interferon
q	0072539	biological_process	T-helper 17 cell differentiation
q	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
q	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
r	0004298	molecular_function	threonine-type endopeptidase activity
r	0005839	cellular_component	proteasome core complex
r	0051603	biological_process	proteolysis involved in protein catabolic process
s	0005839	cellular_component	proteasome core complex
s	0051603	biological_process	proteolysis involved in protein catabolic process
t	0005839	cellular_component	proteasome core complex
t	0051603	biological_process	proteolysis involved in protein catabolic process

Functional Information from PROSITE/UniProt

site_id	PS00388
Number of Residues	23
Details	PROTEASOME_ALPHA_1 Proteasome alpha-type subunits signature. YdraiTvFSPdGHlfQVEYAqeA

Chain	Residue	Details
J	TYR3-ALA25
I	TYR5-ALA27
G	PHE9-ALA31
K	TYR8-ALA30
M	TYR7-ALA29
H	TYR6-ALA28
L	TYR6-ALA28

---

site_id	PS00854
Number of Residues	48
Details	PROTEASOME_BETA_1 Proteasome beta-type subunits signature. LAFkFrhGVIVAADsratagayiasqtvk.KvieinpyllgtmaGgaAD

Chain	Residue	Details
R	LEU4-ASP51
I	LEU35-ASP82
Q	ILE5-ASP52
t	LEU12-ASP59
P	MET12-ASP59
N	MET4-ASP51
s	LEU13-ASP60
O	ALA4-ASP51

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	22
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	24
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"Q9QUM9","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	9
Details	Glycosylation: {"description":"O-linked (GlcNAc) serine","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"P49722","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	4
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"15592455","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	2
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	2
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"P17220","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"17323924","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	2
Details	Modified residue: {"description":"Phosphotyrosine; by ABL1 and ABL2","evidences":[{"source":"PubMed","id":"16678104","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"16964243","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI14
Number of Residues	2
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI15
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI16
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine; alternate","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI17
Number of Residues	2
Details	Glycosylation: {"description":"O-linked (GlcNAc) serine; alternate","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI18
Number of Residues	6
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)"}

Chain

Residue

Details

---

site_id	SWS_FT_FI19
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"17323924","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI20
Number of Residues	6
Details	Active site: {"description":"Nucleophile","evidences":[{"source":"PubMed","id":"25599644","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27493187","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI21
Number of Residues	2
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI22
Number of Residues	2
Details	Modified residue: {"description":"N-acetylserine","evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"JUL-2008","submissionDatabase":"UniProtKB","authors":["Bienvenut W.V.","von Kriegsheim A.F.","Kolch W."]}},{"source":"PubMed","id":"19413330","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22223895","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI23
Number of Residues	2
Details	Modified residue: {"description":"N-acetylmethionine","evidences":[{"source":"PubMed","id":"19413330","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22814378","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI24
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"18502982","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18565852","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19426847","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI25
Number of Residues	2
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"O09061","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---