Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

5VBF

Crystal structure of succinate semialdehyde dehydrogenase from Burkholderia vietnamiensis

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004777	molecular_function	succinate-semialdehyde dehydrogenase (NAD+) activity
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0009013	molecular_function	succinate-semialdehyde dehydrogenase [NAD(P)+] activity
A	0009450	biological_process	gamma-aminobutyric acid catabolic process
A	0016491	molecular_function	oxidoreductase activity
A	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
B	0004777	molecular_function	succinate-semialdehyde dehydrogenase (NAD+) activity
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0009013	molecular_function	succinate-semialdehyde dehydrogenase [NAD(P)+] activity
B	0009450	biological_process	gamma-aminobutyric acid catabolic process
B	0016491	molecular_function	oxidoreductase activity
B	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
C	0004777	molecular_function	succinate-semialdehyde dehydrogenase (NAD+) activity
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0009013	molecular_function	succinate-semialdehyde dehydrogenase [NAD(P)+] activity
C	0009450	biological_process	gamma-aminobutyric acid catabolic process
C	0016491	molecular_function	oxidoreductase activity
C	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
D	0004777	molecular_function	succinate-semialdehyde dehydrogenase (NAD+) activity
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0009013	molecular_function	succinate-semialdehyde dehydrogenase [NAD(P)+] activity
D	0009450	biological_process	gamma-aminobutyric acid catabolic process
D	0016491	molecular_function	oxidoreductase activity
D	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
E	0004777	molecular_function	succinate-semialdehyde dehydrogenase (NAD+) activity
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0009013	molecular_function	succinate-semialdehyde dehydrogenase [NAD(P)+] activity
E	0009450	biological_process	gamma-aminobutyric acid catabolic process
E	0016491	molecular_function	oxidoreductase activity
E	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
F	0004777	molecular_function	succinate-semialdehyde dehydrogenase (NAD+) activity
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0009013	molecular_function	succinate-semialdehyde dehydrogenase [NAD(P)+] activity
F	0009450	biological_process	gamma-aminobutyric acid catabolic process
F	0016491	molecular_function	oxidoreductase activity
F	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
G	0004777	molecular_function	succinate-semialdehyde dehydrogenase (NAD+) activity
G	0005737	cellular_component	cytoplasm
G	0005829	cellular_component	cytosol
G	0009013	molecular_function	succinate-semialdehyde dehydrogenase [NAD(P)+] activity
G	0009450	biological_process	gamma-aminobutyric acid catabolic process
G	0016491	molecular_function	oxidoreductase activity
G	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
H	0004777	molecular_function	succinate-semialdehyde dehydrogenase (NAD+) activity
H	0005737	cellular_component	cytoplasm
H	0005829	cellular_component	cytosol
H	0009013	molecular_function	succinate-semialdehyde dehydrogenase [NAD(P)+] activity
H	0009450	biological_process	gamma-aminobutyric acid catabolic process
H	0016491	molecular_function	oxidoreductase activity
H	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	binding site for residue MES A 601

Chain	Residue
A	ASN158
A	PHE159
A	GLN163
A	VAL289
A	CYS290
A	VAL291
A	PHE453

site_id	AC2
Number of Residues	8
Details	binding site for residue GOL A 602

Chain	Residue
A	GLY129
A	ARG145
A	HOH809
A	HOH949
C	VAL131
C	PRO133
A	THR127
A	TYR128

site_id	AC3
Number of Residues	4
Details	binding site for residue FMT A 603

Chain	Residue
A	GLN163
A	HIS166
A	PHE453
A	GLU464

site_id	AC4
Number of Residues	8
Details	binding site for residue MES B 601

Chain	Residue
B	ASN158
B	PHE159
B	GLN163
B	TYR281
B	VAL289
B	CYS290
B	VAL291
B	PHE453

site_id	AC5
Number of Residues	7
Details	binding site for residue GOL B 602

Chain	Residue
B	THR127
B	TYR128
B	GLY129
B	ARG145
B	HOH826
B	HOH867
D	VAL131

site_id	AC6
Number of Residues	6
Details	binding site for residue FMT B 603

Chain	Residue
B	ASP17
B	ALA57
B	ARG60
B	ALA61
B	PRO204
B	HOH753

site_id	AC7
Number of Residues	8
Details	binding site for residue MES C 601

Chain	Residue
C	ASN158
C	PHE159
C	GLN163
C	VAL289
C	CYS290
C	VAL291
C	GLY447
C	PHE453

site_id	AC8
Number of Residues	7
Details	binding site for residue GOL C 602

Chain	Residue
A	PRO133
C	THR127
C	TYR128
C	GLY129
C	LEU144
C	ARG145
C	HOH716

site_id	AC9
Number of Residues	6
Details	binding site for residue MES D 601

Chain	Residue
D	ASN158
D	PHE159
D	GLN163
D	VAL289
D	CYS290
D	VAL291

site_id	AD1
Number of Residues	7
Details	binding site for residue GOL D 602

Chain	Residue
B	PRO133
D	THR127
D	TYR128
D	GLY129
D	ARG145
D	HOH729
D	HOH759

site_id	AD2
Number of Residues	8
Details	binding site for residue MES E 601

Chain	Residue
E	ASN158
E	PHE159
E	GLN163
E	VAL289
E	CYS290
E	VAL291
E	GLY447
E	PHE453

site_id	AD3
Number of Residues	6
Details	binding site for residue GOL E 602

Chain	Residue
E	THR127
E	TYR128
E	GLY129
E	ARG145
E	HOH830
G	HOH809

site_id	AD4
Number of Residues	7
Details	binding site for residue FMT E 603

Chain	Residue
E	MET482
E	ASN483
E	HOH930
F	ASN442
F	HOH746
H	ALA424
H	ARG425

site_id	AD5
Number of Residues	7
Details	binding site for residue MES F 601

Chain	Residue
F	ASN158
F	PHE159
F	GLN163
F	VAL289
F	CYS290
F	VAL291
F	PHE453

site_id	AD6
Number of Residues	7
Details	binding site for residue GOL F 602

Chain	Residue
F	LEU144
F	ARG145
F	HOH793
H	PRO133
F	THR127
F	TYR128
F	GLY129

site_id	AD7
Number of Residues	8
Details	binding site for residue MES G 601

Chain	Residue
G	ASN158
G	PHE159
G	GLN163
G	TYR281
G	CYS290
G	VAL291
G	PHE453
G	HOH933

site_id	AD8
Number of Residues	8
Details	binding site for residue GOL G 602

Chain	Residue
E	PRO133
G	THR127
G	TYR128
G	GLY129
G	LEU144
G	ARG145
G	HOH712
G	HOH853

site_id	AD9
Number of Residues	8
Details	binding site for residue MES H 601

Chain	Residue
H	ASN158
H	PHE159
H	GLN163
H	VAL289
H	CYS290
H	VAL291
H	GLY447
H	PHE453

site_id	AE1
Number of Residues	7
Details	binding site for residue GOL H 602

Chain	Residue
F	PRO133
H	THR127
H	TYR128
H	GLY129
H	LEU144
H	ARG145
H	HOH707

site_id	AE2
Number of Residues	4
Details	binding site for residue FMT H 603

Chain	Residue
H	ASP8
H	VAL39
H	LEU40
H	HOH815

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)