5V9X

Structure of Mycobacterium smegmatis helicase Lhr bound to ssDNA and AMP-PNP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003676	molecular_function	nucleic acid binding
A	0005524	molecular_function	ATP binding
A	0016818	molecular_function	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue GOL A 902

Chain	Residue
A	VAL90
A	ARG94
A	ARG109
A	ALA344
A	ASP348

---

site_id	AC2
Number of Residues	4
Details	binding site for residue GOL A 903

Chain	Residue
A	ASP125
A	ARG343
A	ALA344
A	GLU347

---

site_id	AC3
Number of Residues	2
Details	binding site for residue GOL A 904

Chain	Residue
A	ALA23
A	SER352

---

site_id	AC4
Number of Residues	6
Details	binding site for residue MG A 906

Chain	Residue
A	ASP170
A	GLU171
A	ANP901
A	HOH1001
A	HOH1003
A	HOH1004

---

site_id	AC5
Number of Residues	3
Details	binding site for residue PEG B 101

Chain	Residue
A	THR178
A	ALA527
B	DT8

---

site_id	AC6
Number of Residues	20
Details	binding site for residues ANP A 901 and GOL A 905

Chain	Residue
A	PHE24
A	ALA26
A	GLN31
A	PRO49
A	THR50
A	GLY53
A	LYS54
A	THR55
A	LEU56
A	ASN95
A	GLU171
A	GLY367
A	ASP369
A	ARG394
A	HIS397
A	VAL399
A	MG906
A	HOH1001
A	HOH1003
A	HOH1004

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	Motif: {"description":"DEAH box","evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	7
Details	Binding site: {"evidences":[{"source":"PubMed","id":"29165676","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"5V9X","evidenceCode":"ECO:0000312"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	15
Details	Binding site: {"evidences":[{"source":"PubMed","id":"29165676","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5V9X","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"29165676","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	Site: {"description":"Forms salt bridge clamp with E-550","evidences":[{"source":"PubMed","id":"29165676","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	Site: {"description":"Wedges between bases of the loading strand","evidences":[{"source":"PubMed","id":"29165676","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	1
Details	Site: {"description":"Forms salt bridge clamp with R-280","evidences":[{"source":"PubMed","id":"29165676","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---