5V6O

Crystal Structure of the highly open channel-stabilized mutant G-2'I + I9'A of GLIC

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004888	molecular_function	transmembrane signaling receptor activity
A	0005216	molecular_function	monoatomic ion channel activity
A	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
A	0005886	cellular_component	plasma membrane
A	0006811	biological_process	monoatomic ion transport
A	0016020	cellular_component	membrane
A	0034220	biological_process	monoatomic ion transmembrane transport
A	0042802	molecular_function	identical protein binding
B	0004888	molecular_function	transmembrane signaling receptor activity
B	0005216	molecular_function	monoatomic ion channel activity
B	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
B	0005886	cellular_component	plasma membrane
B	0006811	biological_process	monoatomic ion transport
B	0016020	cellular_component	membrane
B	0034220	biological_process	monoatomic ion transmembrane transport
B	0042802	molecular_function	identical protein binding
C	0004888	molecular_function	transmembrane signaling receptor activity
C	0005216	molecular_function	monoatomic ion channel activity
C	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
C	0005886	cellular_component	plasma membrane
C	0006811	biological_process	monoatomic ion transport
C	0016020	cellular_component	membrane
C	0034220	biological_process	monoatomic ion transmembrane transport
C	0042802	molecular_function	identical protein binding
D	0004888	molecular_function	transmembrane signaling receptor activity
D	0005216	molecular_function	monoatomic ion channel activity
D	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
D	0005886	cellular_component	plasma membrane
D	0006811	biological_process	monoatomic ion transport
D	0016020	cellular_component	membrane
D	0034220	biological_process	monoatomic ion transmembrane transport
D	0042802	molecular_function	identical protein binding
E	0004888	molecular_function	transmembrane signaling receptor activity
E	0005216	molecular_function	monoatomic ion channel activity
E	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
E	0005886	cellular_component	plasma membrane
E	0006811	biological_process	monoatomic ion transport
E	0016020	cellular_component	membrane
E	0034220	biological_process	monoatomic ion transmembrane transport
E	0042802	molecular_function	identical protein binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue LMT A 401

Chain	Residue
A	ILE240
B	LMT402
D	LMT401
E	ALA234

---

site_id	AC2
Number of Residues	1
Details	binding site for residue CL A 402

Chain	Residue
A	TYR221

---

site_id	AC3
Number of Residues	1
Details	binding site for residue NA A 403

Chain	Residue
E	THR226

---

site_id	AC4
Number of Residues	1
Details	binding site for residue SO4 A 404

Chain	Residue
A	ARG109

---

site_id	AC5
Number of Residues	3
Details	binding site for residue SO4 B 401

Chain	Residue
B	ARG109
A	SER29
B	GLU82

---

site_id	AC6
Number of Residues	3
Details	binding site for residue LMT B 402

Chain	Residue
A	LMT401
B	ALA237
D	LMT401

---

site_id	AC7
Number of Residues	1
Details	binding site for residue CL B 403

Chain	Residue
B	TYR221

---

site_id	AC8
Number of Residues	3
Details	binding site for residue SO4 B 404

Chain	Residue
A	ARG296
B	TYR278
B	GLU282

---

site_id	AC9
Number of Residues	3
Details	binding site for residue SO4 B 405

Chain	Residue
B	ARG293
B	ARG296
C	TYR278

---

site_id	AD1
Number of Residues	5
Details	binding site for residue LMT D 401

Chain	Residue
A	LMT401
B	LMT402
C	LMT403
D	LMT402
E	LMT403

---

site_id	AD2
Number of Residues	7
Details	binding site for residue LMT D 402

Chain	Residue
C	ALA233
C	ALA234
D	ALA233
D	ALA237
D	ILE240
D	LMT401
E	LMT403

---

site_id	AD3
Number of Residues	1
Details	binding site for residue CL D 403

Chain	Residue
D	TYR221

---

site_id	AD4
Number of Residues	3
Details	binding site for residue SO4 D 404

Chain	Residue
D	ARG293
E	TYR278
E	GLU282

---

site_id	AD5
Number of Residues	4
Details	binding site for residue SO4 E 401

Chain	Residue
A	TYR278
A	GLU282
E	ARG293
E	ARG296

---

site_id	AD6
Number of Residues	2
Details	binding site for residue SO4 E 402

Chain	Residue
D	SER29
E	ARG109

---

site_id	AD7
Number of Residues	6
Details	binding site for residue LMT E 403

Chain	Residue
D	ALA233
D	ALA237
D	LMT401
D	LMT402
E	ALA233
E	ALA237

---

site_id	AD8
Number of Residues	1
Details	binding site for residue CL E 404

Chain	Residue
E	TYR221

---

site_id	AD9
Number of Residues	1
Details	binding site for residue SO4 C 401

Chain	Residue
C	ARG109

---

site_id	AE1
Number of Residues	4
Details	binding site for residue SO4 C 402

Chain	Residue
C	ARG293
C	ARG296
D	TYR278
D	GLU282

---

site_id	AE2
Number of Residues	1
Details	binding site for residue LMT C 403

Chain	Residue
D	LMT401

---

site_id	AE3
Number of Residues	1
Details	binding site for residue CL C 404

Chain	Residue
C	TYR221

---

site_id	AE4
Number of Residues	2
Details	binding site for residue SO4 C 405

Chain	Residue
C	SER29
D	ARG109

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	530
Details	Transmembrane: {"description":"Helical"}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	20
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	35
Details	Topological domain: {"description":"Periplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---