5V68

Crystal structure of cell division protein FtsZ from Mycobacterium tuberculosis bounded via the T9 loop

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0000917	biological_process	division septum assembly
A	0003924	molecular_function	GTPase activity
A	0005525	molecular_function	GTP binding
A	0005737	cellular_component	cytoplasm
A	0032153	cellular_component	cell division site
A	0043093	biological_process	FtsZ-dependent cytokinesis
A	0051258	biological_process	protein polymerization
A	0051301	biological_process	cell division
A	0090529	biological_process	cell septum assembly
B	0000166	molecular_function	nucleotide binding
B	0000917	biological_process	division septum assembly
B	0003924	molecular_function	GTPase activity
B	0005525	molecular_function	GTP binding
B	0005737	cellular_component	cytoplasm
B	0032153	cellular_component	cell division site
B	0043093	biological_process	FtsZ-dependent cytokinesis
B	0051258	biological_process	protein polymerization
B	0051301	biological_process	cell division
B	0090529	biological_process	cell septum assembly
C	0000166	molecular_function	nucleotide binding
C	0000917	biological_process	division septum assembly
C	0003924	molecular_function	GTPase activity
C	0005525	molecular_function	GTP binding
C	0005737	cellular_component	cytoplasm
C	0032153	cellular_component	cell division site
C	0043093	biological_process	FtsZ-dependent cytokinesis
C	0051258	biological_process	protein polymerization
C	0051301	biological_process	cell division
C	0090529	biological_process	cell septum assembly
D	0000166	molecular_function	nucleotide binding
D	0000917	biological_process	division septum assembly
D	0003924	molecular_function	GTPase activity
D	0005525	molecular_function	GTP binding
D	0005737	cellular_component	cytoplasm
D	0032153	cellular_component	cell division site
D	0043093	biological_process	FtsZ-dependent cytokinesis
D	0051258	biological_process	protein polymerization
D	0051301	biological_process	cell division
D	0090529	biological_process	cell septum assembly
E	0000166	molecular_function	nucleotide binding
E	0000917	biological_process	division septum assembly
E	0003924	molecular_function	GTPase activity
E	0005525	molecular_function	GTP binding
E	0005737	cellular_component	cytoplasm
E	0032153	cellular_component	cell division site
E	0043093	biological_process	FtsZ-dependent cytokinesis
E	0051258	biological_process	protein polymerization
E	0051301	biological_process	cell division
E	0090529	biological_process	cell septum assembly
F	0000166	molecular_function	nucleotide binding
F	0000917	biological_process	division septum assembly
F	0003924	molecular_function	GTPase activity
F	0005525	molecular_function	GTP binding
F	0005737	cellular_component	cytoplasm
F	0032153	cellular_component	cell division site
F	0043093	biological_process	FtsZ-dependent cytokinesis
F	0051258	biological_process	protein polymerization
F	0051301	biological_process	cell division
F	0090529	biological_process	cell septum assembly

Functional Information from PDB Data

site_id	AC1
Number of Residues	13
Details	binding site for residue GDP B 401

Chain	Residue
B	GLY17
B	GLU136
B	ARG140
B	PHE180
B	ASP184
B	GLY18
B	GLY19
B	ASN22
B	GLY101
B	GLY104
B	GLY105
B	THR106
B	GLY107

---

site_id	AC2
Number of Residues	3
Details	binding site for residue PO4 C 401

Chain	Residue
C	GLY18
C	GLY105
C	THR106

---

site_id	AC3
Number of Residues	14
Details	binding site for residue GDP E 401

Chain	Residue
E	GLY17
E	GLY18
E	GLY19
E	GLY101
E	GLU102
E	GLY103
E	GLY104
E	GLY105
E	THR106
E	GLY107
E	PRO132
E	GLU136
E	PHE180
E	ASP184

---

site_id	AC4
Number of Residues	3
Details	binding site for residue PO4 F 401

Chain	Residue
F	GLY18
F	GLY105
F	THR106

---

Functional Information from PROSITE/UniProt

site_id	PS01134
Number of Residues	35
Details	FTSZ_1 FtsZ protein signature 1. NTDaQaLlmsdadvkldvgrdstr.GlGAGAdPevG

Chain	Residue	Details
A	ASN41-GLY75

---

site_id	PS01135
Number of Residues	22
Details	FTSZ_2 FtsZ protein signature 2. DMvFVTAGeGGGTGTGGAPVVA

Chain	Residue	Details
A	ASP94-ALA115

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	53
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00909","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---