5V49
Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor (Chem 1917)
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0000166 | molecular_function | nucleotide binding |
A | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
A | 0004825 | molecular_function | methionine-tRNA ligase activity |
A | 0005524 | molecular_function | ATP binding |
A | 0006418 | biological_process | tRNA aminoacylation for protein translation |
A | 0006431 | biological_process | methionyl-tRNA aminoacylation |
B | 0000166 | molecular_function | nucleotide binding |
B | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
B | 0004825 | molecular_function | methionine-tRNA ligase activity |
B | 0005524 | molecular_function | ATP binding |
B | 0006418 | biological_process | tRNA aminoacylation for protein translation |
B | 0006431 | biological_process | methionyl-tRNA aminoacylation |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 10 |
Details | binding site for residue MET A 800 |
Chain | Residue |
A | ILE248 |
A | HOH902 |
A | TYR250 |
A | ASP287 |
A | TRP474 |
A | ALA477 |
A | TYR481 |
A | ILE519 |
A | HIS523 |
A | LYS550 |
site_id | AC2 |
Number of Residues | 14 |
Details | binding site for residue 8WA B 801 |
Chain | Residue |
B | PRO247 |
B | ILE248 |
B | TYR250 |
B | ASP287 |
B | HIS289 |
B | GLY290 |
B | LEU456 |
B | VAL473 |
B | TRP474 |
B | TYR481 |
B | ILE519 |
B | HOH907 |
B | HOH943 |
B | HOH945 |
site_id | AC3 |
Number of Residues | 2 |
Details | binding site for residue GOL B 802 |
Chain | Residue |
B | ARG583 |
B | ARG601 |