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5V26

1.78 angstrom crystal structure of P97H 3-hydroxyanthranilate-3,4-dioxygenase from Cupriavidus metallidurans

Functional Information from GO Data
ChainGOidnamespacecontents
A0000334molecular_function3-hydroxyanthranilate 3,4-dioxygenase activity
A0005506molecular_functioniron ion binding
A0006569biological_processtryptophan catabolic process
A0008198molecular_functionferrous iron binding
A0009435biological_processNAD biosynthetic process
A0019363biological_processpyridine nucleotide biosynthetic process
A0019805biological_processquinolinate biosynthetic process
A0034354biological_process'de novo' NAD biosynthetic process from tryptophan
A0043420biological_processanthranilate metabolic process
A0046872molecular_functionmetal ion binding
A0051213molecular_functiondioxygenase activity
B0000334molecular_function3-hydroxyanthranilate 3,4-dioxygenase activity
B0005506molecular_functioniron ion binding
B0006569biological_processtryptophan catabolic process
B0008198molecular_functionferrous iron binding
B0009435biological_processNAD biosynthetic process
B0019363biological_processpyridine nucleotide biosynthetic process
B0019805biological_processquinolinate biosynthetic process
B0034354biological_process'de novo' NAD biosynthetic process from tryptophan
B0043420biological_processanthranilate metabolic process
B0046872molecular_functionmetal ion binding
B0051213molecular_functiondioxygenase activity
Functional Information from PDB Data
site_idAC1
Number of Residues5
Detailsbinding site for residue FE2 A 201
ChainResidue
AHIS51
AGLU57
AHIS95
AHOH372
AHOH373

site_idAC2
Number of Residues5
Detailsbinding site for residue FE2 A 202
ChainResidue
AGLN167
ACYS125
ACYS128
ACYS162
ACYS165

site_idAC3
Number of Residues5
Detailsbinding site for residue FE2 B 201
ChainResidue
BHIS51
BGLU57
BHIS95
BHOH316
BHOH413

site_idAC4
Number of Residues4
Detailsbinding site for residue FE2 B 202
ChainResidue
BCYS125
BCYS128
BCYS162
BCYS165

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues20
DetailsBINDING:
ChainResidueDetails
AARG47
ACYS165
BARG47
BHIS51
BGLU57
BHIS95
BARG99
BGLU110
BCYS125
BCYS128
BCYS162
AHIS51
BCYS165
AGLU57
AHIS95
AARG99
AGLU110
ACYS125
ACYS128
ACYS162

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PDB entries from 2024-07-17

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