5V12

Crystal structure of Carbon Sulfoxide lyase, Egt2 Y134F with sulfenic acid intermediate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0016829	molecular_function	lyase activity
A	0052699	biological_process	ergothioneine biosynthetic process
A	1903257	biological_process	selenoneine biosynthetic process
A	1990411	molecular_function	hercynylcysteine sulfoxide lyase activity (ergothioneine-forming)
B	0005634	cellular_component	nucleus
B	0005737	cellular_component	cytoplasm
B	0016829	molecular_function	lyase activity
B	0052699	biological_process	ergothioneine biosynthetic process
B	1903257	biological_process	selenoneine biosynthetic process
B	1990411	molecular_function	hercynylcysteine sulfoxide lyase activity (ergothioneine-forming)
C	0005634	cellular_component	nucleus
C	0005737	cellular_component	cytoplasm
C	0016829	molecular_function	lyase activity
C	0052699	biological_process	ergothioneine biosynthetic process
C	1903257	biological_process	selenoneine biosynthetic process
C	1990411	molecular_function	hercynylcysteine sulfoxide lyase activity (ergothioneine-forming)
D	0005634	cellular_component	nucleus
D	0005737	cellular_component	cytoplasm
D	0016829	molecular_function	lyase activity
D	0052699	biological_process	ergothioneine biosynthetic process
D	1903257	biological_process	selenoneine biosynthetic process
D	1990411	molecular_function	hercynylcysteine sulfoxide lyase activity (ergothioneine-forming)
E	0005634	cellular_component	nucleus
E	0005737	cellular_component	cytoplasm
E	0016829	molecular_function	lyase activity
E	0052699	biological_process	ergothioneine biosynthetic process
E	1903257	biological_process	selenoneine biosynthetic process
E	1990411	molecular_function	hercynylcysteine sulfoxide lyase activity (ergothioneine-forming)
F	0005634	cellular_component	nucleus
F	0005737	cellular_component	cytoplasm
F	0016829	molecular_function	lyase activity
F	0052699	biological_process	ergothioneine biosynthetic process
F	1903257	biological_process	selenoneine biosynthetic process
F	1990411	molecular_function	hercynylcysteine sulfoxide lyase activity (ergothioneine-forming)
G	0005634	cellular_component	nucleus
G	0005737	cellular_component	cytoplasm
G	0016829	molecular_function	lyase activity
G	0052699	biological_process	ergothioneine biosynthetic process
G	1903257	biological_process	selenoneine biosynthetic process
G	1990411	molecular_function	hercynylcysteine sulfoxide lyase activity (ergothioneine-forming)
H	0005634	cellular_component	nucleus
H	0005737	cellular_component	cytoplasm
H	0016829	molecular_function	lyase activity
H	0052699	biological_process	ergothioneine biosynthetic process
H	1903257	biological_process	selenoneine biosynthetic process
H	1990411	molecular_function	hercynylcysteine sulfoxide lyase activity (ergothioneine-forming)

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue FMT E 501

Chain	Residue
E	SER47
E	SER196
E	GLN224
E	LLP247
E	ARG438
F	8QJ501

---

site_id	AC2
Number of Residues	6
Details	binding site for residue FMT G 501

Chain	Residue
G	LLP247
G	ARG438
G	HOH636
G	SER47
G	SER196
G	GLN224

---

site_id	AC3
Number of Residues	10
Details	binding site for residue 8QJ F 501

Chain	Residue
E	SER47
E	PHE48
E	PHE134
E	LLP247
E	FMT501
E	HOH602
F	ARG75
F	HIS276
F	PHE304
F	THR307

---

site_id	AC4
Number of Residues	5
Details	binding site for residue FMT F 502

Chain	Residue
F	SER47
F	SER196
F	GLN224
F	LLP247
F	ARG438

---

site_id	AC5
Number of Residues	6
Details	binding site for residue FMT H 501

Chain	Residue
H	GLY46
H	SER47
H	SER196
H	GLN224
H	LLP247
H	ARG438

---

site_id	AC6
Number of Residues	6
Details	binding site for residue FMT C 501

Chain	Residue
C	GLY46
C	SER47
C	SER196
C	GLN224
C	EXA247
C	ARG438

---

site_id	AC7
Number of Residues	5
Details	binding site for residue FMT D 501

Chain	Residue
D	SER47
D	SER196
D	GLN224
D	LLP247
D	ARG438

---

site_id	AC8
Number of Residues	6
Details	binding site for residue 8QJ A 501

Chain	Residue
A	PHE134
A	LLP247
B	ARG75
B	HIS276
B	PHE304
B	THR307

---

site_id	AC9
Number of Residues	5
Details	binding site for residue FMT A 502

Chain	Residue
A	SER47
A	SER196
A	GLN224
A	LLP247
A	ARG438

---

site_id	AD1
Number of Residues	5
Details	binding site for residue FMT B 501

Chain	Residue
B	SER47
B	SER196
B	GLN224
B	LLP247
B	ARG438

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	16
Details	Binding site: {"evidences":[{"source":"PubMed","id":"29503207","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5V1X","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	8
Details	Modified residue: {"description":"N6-(pyridoxal phosphate)lysine","evidences":[{"source":"PubMed","id":"29503207","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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