5UX0

X-ray crystal structure of Marinitoga piezophila Argonaute in complex with 5' OH guide RNA and target DNA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003676	molecular_function	nucleic acid binding
A	0004520	molecular_function	DNA endonuclease activity
A	0005737	cellular_component	cytoplasm
D	0003676	molecular_function	nucleic acid binding
D	0004520	molecular_function	DNA endonuclease activity
D	0005737	cellular_component	cytoplasm

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	104
Details	Region: {"description":"Linker L1","evidences":[{"source":"PubMed","id":"27035975","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	164
Details	Region: {"description":"Linker L2","evidences":[{"source":"PubMed","id":"27035975","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	8
Details	Active site: {"evidences":[{"source":"PubMed","id":"27035975","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"Q746M7","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	55
Details	Region: {"description":"PAZ domain","evidences":[{"source":"PubMed","id":"27035975","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	131
Details	Region: {"description":"Mid domain","evidences":[{"source":"PubMed","id":"27035975","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	214
Details	Region: {"description":"PIWI domain","evidences":[{"source":"PubMed","id":"27035975","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---