5UX0

X-ray crystal structure of Marinitoga piezophila Argonaute in complex with 5' OH guide RNA and target DNA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003676	molecular_function	nucleic acid binding
A	0003677	molecular_function	DNA binding
A	0003723	molecular_function	RNA binding
A	0004519	molecular_function	endonuclease activity
A	0004520	molecular_function	DNA endonuclease activity
A	0005737	cellular_component	cytoplasm
A	0006259	biological_process	DNA metabolic process
A	0046872	molecular_function	metal ion binding
D	0003676	molecular_function	nucleic acid binding
D	0003677	molecular_function	DNA binding
D	0003723	molecular_function	RNA binding
D	0004519	molecular_function	endonuclease activity
D	0004520	molecular_function	DNA endonuclease activity
D	0005737	cellular_component	cytoplasm
D	0006259	biological_process	DNA metabolic process
D	0046872	molecular_function	metal ion binding

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	ACT_SITE: ACT_SITE => ECO:0000305|PubMed:27035975

Chain	Residue	Details
A	ASP446
A	GLU482
A	ALA516
A	ASN624
D	ASP446
D	GLU482
D	ALA516
D	ASN624

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site_id	SWS_FT_FI2
Number of Residues	4
Details	BINDING: BINDING => ECO:0000250|UniProtKB:Q746M7

Chain	Residue	Details
A	ASP446
A	ALA516
D	ASP446
D	ALA516

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site_id	SWS_FT_FI3
Number of Residues	2
Details	BINDING: BINDING => ECO:0000305

Chain	Residue	Details
A	ASN624
D	ASN624

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