Functional Information from GO Data
| Chain | GOid | namespace | contents |
| C | 0004114 | molecular_function | 3',5'-cyclic-nucleotide phosphodiesterase activity |
| C | 0007165 | biological_process | signal transduction |
| C | 0008081 | molecular_function | phosphoric diester hydrolase activity |
| D | 0004114 | molecular_function | 3',5'-cyclic-nucleotide phosphodiesterase activity |
| D | 0007165 | biological_process | signal transduction |
| D | 0008081 | molecular_function | phosphoric diester hydrolase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | binding site for residue 8Q7 C 801 |
| Chain | Residue |
| C | TYR524 |
| C | MET713 |
| C | GLN726 |
| C | PHE729 |
| C | HOH914 |
| C | HOH1051 |
| D | LYS705 |
| D | LEU706 |
| D | GLY707 |
| D | HOH1109 |
| C | HIS525 |
| C | LEU675 |
| C | SER677 |
| C | VAL678 |
| C | ILE692 |
| C | TYR693 |
| C | PHE696 |
| C | ILE711 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue ZN C 802 |
| Chain | Residue |
| C | HIS529 |
| C | HIS563 |
| C | ASP564 |
| C | ASP674 |
| C | MG803 |
| C | HOH984 |
| C | HOH1025 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue MG C 803 |
| Chain | Residue |
| C | ASP564 |
| C | ZN802 |
| C | HOH915 |
| C | HOH917 |
| C | HOH984 |
| C | HOH989 |
| C | HOH993 |
| site_id | AC4 |
| Number of Residues | 14 |
| Details | binding site for residue 8Q7 D 801 |
| Chain | Residue |
| D | TYR524 |
| D | HIS525 |
| D | LEU675 |
| D | SER677 |
| D | VAL678 |
| D | ILE692 |
| D | TYR693 |
| D | PHE696 |
| D | MET713 |
| D | GLN726 |
| D | PHE729 |
| D | VAL733 |
| D | HOH919 |
| D | HOH969 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue ZN D 802 |
| Chain | Residue |
| D | HIS529 |
| D | HIS563 |
| D | ASP564 |
| D | ASP674 |
| D | HOH907 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue MG D 803 |
| Chain | Residue |
| D | ASP564 |
| D | HOH901 |
| D | HOH907 |
| D | HOH909 |
| D | HOH946 |
| D | HOH1008 |
Functional Information from PROSITE/UniProt
| site_id | PS00126 |
| Number of Residues | 12 |
| Details | PDEASE_I_1 3'5'-cyclic nucleotide phosphodiesterase domain signature. HDLdHrGfsNsY |
| Chain | Residue | Details |
| C | HIS563-TYR574 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"UniProtKB","id":"O76083","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17389385","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 317 |
| Details | Domain: {"description":"PDEase","evidences":[{"source":"PROSITE-ProRule","id":"PRU01192","evidenceCode":"ECO:0000255"}]} |
