5USW
The crystal structure of 7,8-dihydropteroate synthase from Vibrio fischeri ES114
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004156 | molecular_function | dihydropteroate synthase activity |
A | 0005829 | cellular_component | cytosol |
A | 0009396 | biological_process | folic acid-containing compound biosynthetic process |
A | 0016740 | molecular_function | transferase activity |
A | 0042558 | biological_process | pteridine-containing compound metabolic process |
A | 0044237 | biological_process | cellular metabolic process |
A | 0046654 | biological_process | tetrahydrofolate biosynthetic process |
A | 0046656 | biological_process | folic acid biosynthetic process |
A | 0046872 | molecular_function | metal ion binding |
B | 0004156 | molecular_function | dihydropteroate synthase activity |
B | 0005829 | cellular_component | cytosol |
B | 0009396 | biological_process | folic acid-containing compound biosynthetic process |
B | 0016740 | molecular_function | transferase activity |
B | 0042558 | biological_process | pteridine-containing compound metabolic process |
B | 0044237 | biological_process | cellular metabolic process |
B | 0046654 | biological_process | tetrahydrofolate biosynthetic process |
B | 0046656 | biological_process | folic acid biosynthetic process |
B | 0046872 | molecular_function | metal ion binding |
C | 0004156 | molecular_function | dihydropteroate synthase activity |
C | 0005829 | cellular_component | cytosol |
C | 0009396 | biological_process | folic acid-containing compound biosynthetic process |
C | 0016740 | molecular_function | transferase activity |
C | 0042558 | biological_process | pteridine-containing compound metabolic process |
C | 0044237 | biological_process | cellular metabolic process |
C | 0046654 | biological_process | tetrahydrofolate biosynthetic process |
C | 0046656 | biological_process | folic acid biosynthetic process |
C | 0046872 | molecular_function | metal ion binding |
D | 0004156 | molecular_function | dihydropteroate synthase activity |
D | 0005829 | cellular_component | cytosol |
D | 0009396 | biological_process | folic acid-containing compound biosynthetic process |
D | 0016740 | molecular_function | transferase activity |
D | 0042558 | biological_process | pteridine-containing compound metabolic process |
D | 0044237 | biological_process | cellular metabolic process |
D | 0046654 | biological_process | tetrahydrofolate biosynthetic process |
D | 0046656 | biological_process | folic acid biosynthetic process |
D | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 8 |
Details | binding site for residue GOL A 301 |
Chain | Residue |
A | HIS140 |
A | GLN142 |
A | LEU157 |
A | ILE161 |
A | PRO186 |
A | LYS192 |
A | HIS196 |
A | HOH479 |
site_id | AC2 |
Number of Residues | 4 |
Details | binding site for residue GOL A 302 |
Chain | Residue |
A | ARG88 |
A | PHE89 |
A | HOH474 |
A | GLU45 |
site_id | AC3 |
Number of Residues | 7 |
Details | binding site for residue GOL A 303 |
Chain | Residue |
A | ASN115 |
A | VAL117 |
A | ASP185 |
A | PHE190 |
A | LYS221 |
A | HOH425 |
A | HOH428 |
site_id | AC4 |
Number of Residues | 2 |
Details | binding site for residue FMT A 304 |
Chain | Residue |
A | ASN7 |
A | HOH513 |
site_id | AC5 |
Number of Residues | 5 |
Details | binding site for residue ACT A 305 |
Chain | Residue |
A | ARG220 |
A | PRO232 |
A | LYS233 |
A | LEU236 |
A | ASP258 |
site_id | AC6 |
Number of Residues | 8 |
Details | binding site for residue GOL B 301 |
Chain | Residue |
B | HIS140 |
B | GLN142 |
B | LEU157 |
B | ILE161 |
B | PRO186 |
B | LYS192 |
B | HIS196 |
B | HOH449 |
site_id | AC7 |
Number of Residues | 1 |
Details | binding site for residue GOL B 302 |
Chain | Residue |
B | GLN252 |
site_id | AC8 |
Number of Residues | 6 |
Details | binding site for residue FMT B 303 |
Chain | Residue |
B | MSE139 |
B | ASP185 |
B | LYS221 |
B | ARG255 |
B | HOH438 |
B | HOH572 |
site_id | AC9 |
Number of Residues | 5 |
Details | binding site for residue FMT B 304 |
Chain | Residue |
B | LYS8 |
B | HIS86 |
B | PHE89 |
B | ASP90 |
B | HOH460 |
site_id | AD1 |
Number of Residues | 2 |
Details | binding site for residue FMT B 305 |
Chain | Residue |
B | LYS192 |
B | HOH419 |
site_id | AD2 |
Number of Residues | 8 |
Details | binding site for residue GOL C 301 |
Chain | Residue |
C | HIS140 |
C | GLN142 |
C | LEU157 |
C | ILE161 |
C | PRO186 |
C | LYS192 |
C | HIS196 |
C | HOH459 |
site_id | AD3 |
Number of Residues | 8 |
Details | binding site for residue GOL C 302 |
Chain | Residue |
C | ASN115 |
C | VAL117 |
C | ASP185 |
C | PHE190 |
C | LYS221 |
C | ARG255 |
C | HOH416 |
C | HOH418 |
site_id | AD4 |
Number of Residues | 8 |
Details | binding site for residue GOL D 301 |
Chain | Residue |
D | HIS140 |
D | GLN142 |
D | LEU157 |
D | ILE161 |
D | PRO186 |
D | LYS192 |
D | HIS196 |
D | HOH426 |
site_id | AD5 |
Number of Residues | 10 |
Details | binding site for residue GOL D 302 |
Chain | Residue |
D | ASN115 |
D | VAL117 |
D | ASP185 |
D | PHE190 |
D | LYS221 |
D | ARG255 |
D | HOH405 |
D | HOH410 |
D | HOH412 |
D | HOH416 |
Functional Information from PROSITE/UniProt
site_id | PS00792 |
Number of Residues | 16 |
Details | DHPS_1 Dihydropteroate synthase signature 1. VmGILNvTpDSFsDgG |
Chain | Residue | Details |
A | VAL17-GLY32 |