5USW
The crystal structure of 7,8-dihydropteroate synthase from Vibrio fischeri ES114
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004156 | molecular_function | dihydropteroate synthase activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0009396 | biological_process | folic acid-containing compound biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0042558 | biological_process | pteridine-containing compound metabolic process |
| A | 0046654 | biological_process | tetrahydrofolate biosynthetic process |
| A | 0046656 | biological_process | folic acid biosynthetic process |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0004156 | molecular_function | dihydropteroate synthase activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0009396 | biological_process | folic acid-containing compound biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0042558 | biological_process | pteridine-containing compound metabolic process |
| B | 0046654 | biological_process | tetrahydrofolate biosynthetic process |
| B | 0046656 | biological_process | folic acid biosynthetic process |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0004156 | molecular_function | dihydropteroate synthase activity |
| C | 0005829 | cellular_component | cytosol |
| C | 0009396 | biological_process | folic acid-containing compound biosynthetic process |
| C | 0016740 | molecular_function | transferase activity |
| C | 0042558 | biological_process | pteridine-containing compound metabolic process |
| C | 0046654 | biological_process | tetrahydrofolate biosynthetic process |
| C | 0046656 | biological_process | folic acid biosynthetic process |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0004156 | molecular_function | dihydropteroate synthase activity |
| D | 0005829 | cellular_component | cytosol |
| D | 0009396 | biological_process | folic acid-containing compound biosynthetic process |
| D | 0016740 | molecular_function | transferase activity |
| D | 0042558 | biological_process | pteridine-containing compound metabolic process |
| D | 0046654 | biological_process | tetrahydrofolate biosynthetic process |
| D | 0046656 | biological_process | folic acid biosynthetic process |
| D | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 301 |
| Chain | Residue |
| A | HIS140 |
| A | GLN142 |
| A | LEU157 |
| A | ILE161 |
| A | PRO186 |
| A | LYS192 |
| A | HIS196 |
| A | HOH479 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 302 |
| Chain | Residue |
| A | ARG88 |
| A | PHE89 |
| A | HOH474 |
| A | GLU45 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 303 |
| Chain | Residue |
| A | ASN115 |
| A | VAL117 |
| A | ASP185 |
| A | PHE190 |
| A | LYS221 |
| A | HOH425 |
| A | HOH428 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue FMT A 304 |
| Chain | Residue |
| A | ASN7 |
| A | HOH513 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue ACT A 305 |
| Chain | Residue |
| A | ARG220 |
| A | PRO232 |
| A | LYS233 |
| A | LEU236 |
| A | ASP258 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | binding site for residue GOL B 301 |
| Chain | Residue |
| B | HIS140 |
| B | GLN142 |
| B | LEU157 |
| B | ILE161 |
| B | PRO186 |
| B | LYS192 |
| B | HIS196 |
| B | HOH449 |
| site_id | AC7 |
| Number of Residues | 1 |
| Details | binding site for residue GOL B 302 |
| Chain | Residue |
| B | GLN252 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue FMT B 303 |
| Chain | Residue |
| B | MSE139 |
| B | ASP185 |
| B | LYS221 |
| B | ARG255 |
| B | HOH438 |
| B | HOH572 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue FMT B 304 |
| Chain | Residue |
| B | LYS8 |
| B | HIS86 |
| B | PHE89 |
| B | ASP90 |
| B | HOH460 |
| site_id | AD1 |
| Number of Residues | 2 |
| Details | binding site for residue FMT B 305 |
| Chain | Residue |
| B | LYS192 |
| B | HOH419 |
| site_id | AD2 |
| Number of Residues | 8 |
| Details | binding site for residue GOL C 301 |
| Chain | Residue |
| C | HIS140 |
| C | GLN142 |
| C | LEU157 |
| C | ILE161 |
| C | PRO186 |
| C | LYS192 |
| C | HIS196 |
| C | HOH459 |
| site_id | AD3 |
| Number of Residues | 8 |
| Details | binding site for residue GOL C 302 |
| Chain | Residue |
| C | ASN115 |
| C | VAL117 |
| C | ASP185 |
| C | PHE190 |
| C | LYS221 |
| C | ARG255 |
| C | HOH416 |
| C | HOH418 |
| site_id | AD4 |
| Number of Residues | 8 |
| Details | binding site for residue GOL D 301 |
| Chain | Residue |
| D | HIS140 |
| D | GLN142 |
| D | LEU157 |
| D | ILE161 |
| D | PRO186 |
| D | LYS192 |
| D | HIS196 |
| D | HOH426 |
| site_id | AD5 |
| Number of Residues | 10 |
| Details | binding site for residue GOL D 302 |
| Chain | Residue |
| D | ASN115 |
| D | VAL117 |
| D | ASP185 |
| D | PHE190 |
| D | LYS221 |
| D | ARG255 |
| D | HOH405 |
| D | HOH410 |
| D | HOH412 |
| D | HOH416 |
Functional Information from PROSITE/UniProt
| site_id | PS00792 |
| Number of Residues | 16 |
| Details | DHPS_1 Dihydropteroate synthase signature 1. VmGILNvTpDSFsDgG |
| Chain | Residue | Details |
| A | VAL17-GLY32 |
