5UMU
Crystal structure of the middle double PH domain of human FACT complex subunit SPT16
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue FMT A 1001 |
| Chain | Residue |
| A | TYR811 |
| A | PHE833 |
| A | VAL834 |
| A | HOH1207 |
| site_id | AC2 |
| Number of Residues | 1 |
| Details | binding site for residue FMT A 1002 |
| Chain | Residue |
| A | GLN898 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue FMT A 1003 |
| Chain | Residue |
| B | ASN656 |
| A | LYS892 |
| A | FMT1006 |
| A | HOH1173 |
| B | ASN654 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | binding site for residue FMT A 1004 |
| Chain | Residue |
| A | ASN901 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue FMT A 1005 |
| Chain | Residue |
| A | ILE671 |
| A | LYS696 |
| A | PHE730 |
| A | GLY731 |
| A | FMT1007 |
| A | HOH1102 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue FMT A 1006 |
| Chain | Residue |
| A | LYS892 |
| A | THR894 |
| A | TRP922 |
| A | GLU926 |
| A | FMT1003 |
| A | HOH1140 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue FMT A 1007 |
| Chain | Residue |
| A | ASP695 |
| A | FMT1005 |
| A | HOH1116 |
| A | HOH1257 |
| B | ASN887 |
| B | TYR893 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | binding site for residue FMT A 1008 |
| Chain | Residue |
| A | SER821 |
| A | SER822 |
| A | HOH1104 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | binding site for residue FMT A 1009 |
| Chain | Residue |
| A | TYR741 |
| A | GLU743 |
| site_id | AD1 |
| Number of Residues | 4 |
| Details | binding site for residue FMT A 1010 |
| Chain | Residue |
| A | LYS696 |
| A | VAL697 |
| A | ASP698 |
| A | HOH1102 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue FMT A 1011 |
| Chain | Residue |
| A | PHE924 |
| A | HOH1101 |
| A | HOH1109 |
| A | HOH1131 |
| site_id | AD3 |
| Number of Residues | 4 |
| Details | binding site for residue FMT A 1012 |
| Chain | Residue |
| A | LEU837 |
| A | ASP838 |
| A | CYS889 |
| A | HOH1103 |
| site_id | AD4 |
| Number of Residues | 5 |
| Details | binding site for residue FMT B 1001 |
| Chain | Residue |
| B | LYS892 |
| B | TRP922 |
| B | GLU926 |
| B | ACT1015 |
| B | HOH1198 |
| site_id | AD5 |
| Number of Residues | 6 |
| Details | binding site for residue FMT B 1002 |
| Chain | Residue |
| B | VAL876 |
| B | ALA877 |
| B | LEU879 |
| B | ASP880 |
| B | HOH1115 |
| B | HOH1131 |
| site_id | AD6 |
| Number of Residues | 5 |
| Details | binding site for residue FMT B 1003 |
| Chain | Residue |
| B | LYS663 |
| B | ASP664 |
| B | GLY678 |
| B | SER679 |
| B | VAL692 |
| site_id | AD7 |
| Number of Residues | 4 |
| Details | binding site for residue FMT B 1004 |
| Chain | Residue |
| A | LYS862 |
| B | SER658 |
| B | PRO660 |
| B | HOH1116 |
| site_id | AD8 |
| Number of Residues | 4 |
| Details | binding site for residue FMT B 1005 |
| Chain | Residue |
| B | GLU788 |
| B | PHE797 |
| B | FMT1006 |
| B | HOH1176 |
| site_id | AD9 |
| Number of Residues | 4 |
| Details | binding site for residue FMT B 1006 |
| Chain | Residue |
| B | PHE709 |
| B | FMT1005 |
| B | HOH1219 |
| B | HOH1230 |
| site_id | AE1 |
| Number of Residues | 4 |
| Details | binding site for residue FMT B 1007 |
| Chain | Residue |
| B | ARG734 |
| B | THR736 |
| B | FMT1018 |
| B | HOH1113 |
| site_id | AE2 |
| Number of Residues | 5 |
| Details | binding site for residue FMT B 1008 |
| Chain | Residue |
| B | ARG812 |
| B | SER813 |
| B | PRO831 |
| B | HOH1178 |
| B | HOH1201 |
| site_id | AE3 |
| Number of Residues | 4 |
| Details | binding site for residue FMT B 1009 |
| Chain | Residue |
| B | GLN898 |
| B | PHE924 |
| B | HOH1140 |
| B | HOH1150 |
| site_id | AE4 |
| Number of Residues | 4 |
| Details | binding site for residue FMT B 1010 |
| Chain | Residue |
| B | VAL848 |
| B | LYS883 |
| B | GLU895 |
| B | HOH1102 |
| site_id | AE5 |
| Number of Residues | 4 |
| Details | binding site for residue FMT B 1011 |
| Chain | Residue |
| B | TYR811 |
| B | PHE833 |
| B | VAL834 |
| B | HOH1169 |
| site_id | AE6 |
| Number of Residues | 7 |
| Details | binding site for residue ACT B 1012 |
| Chain | Residue |
| B | HOH1130 |
| B | HOH1137 |
| B | HOH1256 |
| B | LYS696 |
| B | VAL697 |
| B | ASP698 |
| B | MSE729 |
| site_id | AE7 |
| Number of Residues | 4 |
| Details | binding site for residue ACT B 1013 |
| Chain | Residue |
| B | PRO669 |
| B | ASN670 |
| B | HOH1101 |
| B | HOH1208 |
| site_id | AE8 |
| Number of Residues | 5 |
| Details | binding site for residue ACT B 1014 |
| Chain | Residue |
| A | SER658 |
| A | PRO660 |
| A | HOH1255 |
| B | ASP838 |
| B | LYS862 |
| site_id | AE9 |
| Number of Residues | 6 |
| Details | binding site for residue ACT B 1015 |
| Chain | Residue |
| A | ASN654 |
| A | ASN656 |
| B | LEU842 |
| B | FMT1001 |
| B | HOH1106 |
| B | HOH1198 |
| site_id | AF1 |
| Number of Residues | 3 |
| Details | binding site for residue ACT B 1016 |
| Chain | Residue |
| A | SER888 |
| A | HOH1330 |
| B | ARG693 |
| site_id | AF2 |
| Number of Residues | 2 |
| Details | binding site for residue FMT B 1017 |
| Chain | Residue |
| B | TYR741 |
| B | GLU743 |
| site_id | AF3 |
| Number of Residues | 7 |
| Details | binding site for residue FMT B 1018 |
| Chain | Residue |
| B | THR736 |
| B | ASP737 |
| B | PRO831 |
| B | PRO832 |
| B | FMT1007 |
| B | HOH1107 |
| B | HOH1148 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
