5UMH
Crystal Structure of Catechol 1,2-dioxygenase protein from Burkholderia multivorans
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0005506 | molecular_function | iron ion binding |
| A | 0006725 | biological_process | obsolete cellular aromatic compound metabolic process |
| A | 0008199 | molecular_function | ferric iron binding |
| A | 0009712 | biological_process | catechol-containing compound metabolic process |
| A | 0016702 | molecular_function | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen |
| A | 0018576 | molecular_function | catechol 1,2-dioxygenase activity |
| A | 0019614 | biological_process | catechol-containing compound catabolic process |
| A | 0042952 | biological_process | beta-ketoadipate pathway |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051213 | molecular_function | dioxygenase activity |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0005506 | molecular_function | iron ion binding |
| B | 0006725 | biological_process | obsolete cellular aromatic compound metabolic process |
| B | 0008199 | molecular_function | ferric iron binding |
| B | 0009712 | biological_process | catechol-containing compound metabolic process |
| B | 0016702 | molecular_function | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen |
| B | 0018576 | molecular_function | catechol 1,2-dioxygenase activity |
| B | 0019614 | biological_process | catechol-containing compound catabolic process |
| B | 0042952 | biological_process | beta-ketoadipate pathway |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0051213 | molecular_function | dioxygenase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue ZN A 401 |
| Chain | Residue |
| A | TYR164 |
| A | TYR200 |
| A | HIS224 |
| A | HIS226 |
| A | EDO402 |
| A | HOH507 |
| A | HOH797 |
| site_id | AC2 |
| Number of Residues | 11 |
| Details | binding site for residue EDO A 402 |
| Chain | Residue |
| A | TYR164 |
| A | TYR200 |
| A | ARG221 |
| A | HIS224 |
| A | HIS226 |
| A | ZN401 |
| A | HOH507 |
| A | HOH797 |
| A | HOH925 |
| A | GLY107 |
| A | PRO108 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue CA A 403 |
| Chain | Residue |
| A | HOH603 |
| A | HOH727 |
| A | HOH763 |
| A | HOH954 |
| A | HOH1008 |
| A | HOH1074 |
| A | HOH1076 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue CL A 404 |
| Chain | Residue |
| A | HIS166 |
| A | ASP168 |
| A | ALA172 |
| A | GLN173 |
| A | EDO409 |
| A | HOH781 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue PG4 A 405 |
| Chain | Residue |
| A | TYR61 |
| A | LEU211 |
| A | PG6406 |
| B | PHE30 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue PG6 A 406 |
| Chain | Residue |
| A | GLU54 |
| A | LEU62 |
| A | PG4405 |
| B | ALA71 |
| B | LEU80 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue PG6 A 407 |
| Chain | Residue |
| A | ASN27 |
| A | PHE30 |
| A | HOH519 |
| B | TYR61 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 408 |
| Chain | Residue |
| A | ASN60 |
| A | ASN63 |
| A | GLN67 |
| A | HOH521 |
| A | HOH547 |
| A | HOH659 |
| B | HOH619 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 409 |
| Chain | Residue |
| A | HIS166 |
| A | GLN173 |
| A | CL404 |
| A | HOH504 |
| site_id | AD1 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 410 |
| Chain | Residue |
| A | LEU37 |
| A | ASP40 |
| A | LEU41 |
| A | HOH513 |
| A | HOH539 |
| B | LEU37 |
| B | ASP40 |
| site_id | AD2 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 411 |
| Chain | Residue |
| A | ILE249 |
| A | ASP252 |
| A | TYR255 |
| A | ALA256 |
| A | THR257 |
| A | HOH728 |
| site_id | AD3 |
| Number of Residues | 7 |
| Details | binding site for residue ZN B 401 |
| Chain | Residue |
| B | TYR164 |
| B | TYR200 |
| B | HIS224 |
| B | HIS226 |
| B | EDO402 |
| B | HOH501 |
| B | HOH511 |
| site_id | AD4 |
| Number of Residues | 11 |
| Details | binding site for residue EDO B 402 |
| Chain | Residue |
| B | LEU109 |
| B | TYR164 |
| B | TYR200 |
| B | ARG221 |
| B | HIS224 |
| B | HIS226 |
| B | ZN401 |
| B | HOH501 |
| B | HOH511 |
| B | HOH653 |
| B | HOH746 |
| site_id | AD5 |
| Number of Residues | 3 |
| Details | binding site for residue PG4 B 403 |
| Chain | Residue |
| A | LEU80 |
| B | GLU54 |
| B | LEU62 |
| site_id | AD6 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 404 |
| Chain | Residue |
| B | ARG217 |
| B | HIS218 |
| B | ASP251 |
| B | PHE253 |
| B | HOH534 |
| B | HOH814 |
| site_id | AD7 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 405 |
| Chain | Residue |
| B | HOH658 |
| B | ASP118 |
| B | GLY119 |
| B | ASP185 |
| B | HOH582 |
| site_id | AD8 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 406 |
| Chain | Residue |
| B | HIS166 |
| B | ASP168 |
| B | ALA172 |
| B | GLN173 |
| B | HOH574 |
Functional Information from PROSITE/UniProt
| site_id | PS00083 |
| Number of Residues | 29 |
| Details | INTRADIOL_DIOXYGENAS Intradiol ring-cleavage dioxygenases signature. IrGtVtgtdGkpLagalVECwhanskGfY |
| Chain | Residue | Details |
| A | ILE136-TYR164 |
