5UM9
Flap endonuclease 1 (FEN1) D86N with 5'-flap substrate DNA and Sm3+
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue K A 401 |
| Chain | Residue |
| A | SER237 |
| A | ILE238 |
| A | ILE241 |
| D | DT5 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue SM A 402 |
| Chain | Residue |
| E | DT7 |
| A | GLU160 |
| A | ASP179 |
| A | ASP181 |
| A | HOH502 |
| A | HOH506 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue SM A 403 |
| Chain | Residue |
| A | GLU57 |
| A | GLU285 |
| A | GLU313 |
| A | GLN342 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue SM A 404 |
| Chain | Residue |
| A | GLU57 |
| A | GLU59 |
| A | GLU313 |
| A | GLN342 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue SM A 405 |
| Chain | Residue |
| A | HOH508 |
| A | HOH517 |
| D | HOH107 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue SM A 406 |
| Chain | Residue |
| A | GLU338 |
| A | HOH501 |
| A | HOH507 |
| A | HOH518 |
Functional Information from PROSITE/UniProt
| site_id | PS00842 |
| Number of Residues | 15 |
| Details | XPG_2 XPG protein signature 2. GIPYLdAPsEAEASC |
| Chain | Residue | Details |
| A | GLY149-CYS163 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 131 |
| Details | Region: {"description":"I-domain"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15616578","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1UL1","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | Binding site: {} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15616578","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1UL1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5FV7","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15616578","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1UL1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5FV7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5ZOD","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PDB","id":"5FV7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5ZOD","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PDB","id":"5ZOD","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"Symmetric dimethylarginine; by PRMT5","evidences":[{"source":"HAMAP-Rule","id":"MF_03140","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"20729856","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine; by CDK2","evidences":[{"source":"HAMAP-Rule","id":"MF_03140","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"20729856","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI12 |
| Number of Residues | 3 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI13 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
