Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0005737 | cellular_component | cytoplasm |
A | 0006749 | biological_process | glutathione metabolic process |
A | 0009235 | biological_process | cobalamin metabolic process |
A | 0016491 | molecular_function | oxidoreductase activity |
A | 0031419 | molecular_function | cobalamin binding |
A | 0032451 | molecular_function | demethylase activity |
A | 0033787 | molecular_function | cyanocobalamin reductase (cyanide-eliminating) (NADP+) activity |
A | 0043295 | molecular_function | glutathione binding |
A | 0055114 | biological_process | obsolete oxidation-reduction process |
A | 0070988 | biological_process | demethylation |
A | 0071949 | molecular_function | FAD binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 37 |
Details | binding site for residue COB A 300 |
Chain | Residue |
A | ALA38 |
A | TYR146 |
A | GLN148 |
A | LEU169 |
A | LYS170 |
A | ILE172 |
A | LEU174 |
A | SER175 |
A | PHE186 |
A | PHE222 |
A | ASN223 |
A | VAL39 |
A | TRP226 |
A | PHE249 |
A | TYR268 |
A | TLA301 |
A | GOL304 |
A | HOH404 |
A | HOH450 |
A | HOH452 |
A | HOH459 |
A | HOH466 |
A | ASP121 |
A | HOH467 |
A | HOH472 |
A | HOH477 |
A | HOH498 |
A | HOH515 |
A | HOH523 |
A | HOH547 |
A | HOH601 |
A | ILE132 |
A | LEU133 |
A | MET134 |
A | GLN135 |
A | THR136 |
A | HIS139 |
site_id | AC2 |
Number of Residues | 9 |
Details | binding site for residue TLA A 301 |
Chain | Residue |
A | ARG187 |
A | ARG232 |
A | TYR241 |
A | PHE249 |
A | GLN270 |
A | COB300 |
A | HOH407 |
A | HOH421 |
A | HOH453 |
site_id | AC3 |
Number of Residues | 12 |
Details | binding site for residue TLA A 302 |
Chain | Residue |
A | MET89 |
A | VAL90 |
A | SER91 |
A | SER92 |
A | SER96 |
A | SER242 |
A | THR243 |
A | THR244 |
A | HOH411 |
A | HOH424 |
A | HOH470 |
A | HOH499 |
site_id | AC4 |
Number of Residues | 8 |
Details | binding site for residue TAR A 303 |
Chain | Residue |
A | PRO161 |
A | GLY163 |
A | ARG164 |
A | MET165 |
A | LEU169 |
A | LYS170 |
A | PHE171 |
A | HOH436 |
site_id | AC5 |
Number of Residues | 3 |
Details | binding site for residue GOL A 304 |
Chain | Residue |
A | TYR268 |
A | COB300 |
A | HOH421 |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | ASP121 | |
A | ILE132 | |
A | TYR146 | |