Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0000166 | molecular_function | nucleotide binding |
A | 0004550 | molecular_function | nucleoside diphosphate kinase activity |
A | 0004798 | molecular_function | thymidylate kinase activity |
A | 0005524 | molecular_function | ATP binding |
A | 0005634 | cellular_component | nucleus |
A | 0005737 | cellular_component | cytoplasm |
A | 0006227 | biological_process | dUDP biosynthetic process |
A | 0006233 | biological_process | dTDP biosynthetic process |
A | 0006235 | biological_process | dTTP biosynthetic process |
A | 0009041 | molecular_function | UMP/dUMP kinase activity |
A | 0016301 | molecular_function | kinase activity |
A | 0016310 | biological_process | phosphorylation |
A | 0046872 | molecular_function | metal ion binding |
A | 0046940 | biological_process | nucleoside monophosphate phosphorylation |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 17 |
Details | binding site for residue TMP A 301 |
Chain | Residue |
A | LYS35 |
A | HOH411 |
A | HOH413 |
A | HOH424 |
A | HOH428 |
A | HOH430 |
A | HOH436 |
A | HOH440 |
A | HOH454 |
A | ARG39 |
A | LEU51 |
A | PHE67 |
A | ARG71 |
A | ARG92 |
A | GLY97 |
A | TYR100 |
A | TYR161 |
site_id | AC2 |
Number of Residues | 18 |
Details | binding site for residue ADP A 302 |
Chain | Residue |
A | LEU12 |
A | ASP13 |
A | ARG14 |
A | SER15 |
A | GLY16 |
A | LYS17 |
A | SER18 |
A | THR19 |
A | ARG153 |
A | LYS154 |
A | LYS194 |
A | THR195 |
A | ILE196 |
A | MG303 |
A | HOH416 |
A | HOH417 |
A | HOH432 |
A | HOH443 |
site_id | AC3 |
Number of Residues | 6 |
Details | binding site for residue MG A 303 |
Chain | Residue |
A | ASP13 |
A | ADP302 |
A | HOH424 |
A | HOH432 |
A | HOH454 |
A | HOH471 |
site_id | AC4 |
Number of Residues | 4 |
Details | binding site for residue MG A 304 |
Chain | Residue |
A | ASP13 |
A | GLY155 |
A | GLU162 |
A | HOH450 |
Functional Information from PROSITE/UniProt
site_id | PS01331 |
Number of Residues | 13 |
Details | THYMIDYLATE_KINASE Thymidylate kinase signature. ILDRYiySGiAYT |
Chain | Residue | Details |
A | ILE89-THR101 | |