5UFE

Wild-type K-Ras(GNP)/R11.1.6 complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003924	molecular_function	GTPase activity
A	0005525	molecular_function	GTP binding
A	0007165	biological_process	signal transduction
A	0016020	cellular_component	membrane
B	0003677	molecular_function	DNA binding
B	0004521	molecular_function	RNA endonuclease activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	31
Details	binding site for residue GNP A 201

Chain	Residue
A	GLY13
A	ASP119
A	LEU120
A	SER145
A	ALA146
A	LYS147
A	CD206
A	CL208
A	MG211
A	HOH302
A	HOH305
A	VAL14
A	HOH316
A	HOH317
A	HOH319
A	HOH320
A	HOH326
A	HOH328
A	HOH330
A	HOH334
A	HOH350
B	ASP15
A	GLY15
B	LYS18
B	HOH203
A	LYS16
A	SER17
A	ALA18
A	GLY60
A	ASN116
A	LYS117

---

site_id	AC2
Number of Residues	5
Details	binding site for residue CA A 202

Chain	Residue
A	GLU31
A	CL208
A	HOH306
A	HOH317
A	HOH365

---

site_id	AC3
Number of Residues	4
Details	binding site for residue CA A 203

Chain	Residue
A	ASP108
A	HOH308
A	HOH338
A	HOH351

---

site_id	AC4
Number of Residues	4
Details	binding site for residue CD A 204

Chain	Residue
A	GLU37
A	GLU62
A	HOH367
B	LYS32

---

site_id	AC5
Number of Residues	5
Details	binding site for residue CD A 205

Chain	Residue
A	HIS94
A	GLU98
A	CYS118
A	CL209
A	CO214

---

site_id	AC6
Number of Residues	5
Details	binding site for residue CD A 206

Chain	Residue
A	ASP33
A	GNP201
A	HOH368
B	ALA1
B	HOH203

---

site_id	AC7
Number of Residues	4
Details	binding site for residue CD A 207

Chain	Residue
A	GLU91
A	ASP154
A	HOH356
A	HOH371

---

site_id	AC8
Number of Residues	4
Details	binding site for residue CL A 208

Chain	Residue
A	GNP201
A	CA202
B	ASP15
B	LYS18

---

site_id	AC9
Number of Residues	3
Details	binding site for residue CL A 209

Chain	Residue
A	ASP119
A	THR148
A	CD205

---

site_id	AD1
Number of Residues	5
Details	binding site for residue CL A 210

Chain	Residue
A	HIS95
A	ARG123
A	GLU143
A	CO214
A	HOH329

---

site_id	AD2
Number of Residues	5
Details	binding site for residue MG A 211

Chain	Residue
A	SER17
A	GNP201
A	HOH305
A	HOH319
A	HOH326

---

site_id	AD3
Number of Residues	6
Details	binding site for residue CO A 212

Chain	Residue
A	GLU3
A	GLU76
A	HOH336
A	HOH341
B	GLU11
B	HOH201

---

site_id	AD4
Number of Residues	4
Details	binding site for residue CO A 213

Chain	Residue
A	HIS27
A	ASP105
A	HOH304
A	HOH331

---

site_id	AD5
Number of Residues	8
Details	binding site for residue CO A 214

Chain	Residue
A	HIS95
A	GLU98
A	CYS118
A	GLU143
A	CD205
A	CL210
A	HOH310
A	HOH329

---

site_id	AD6
Number of Residues	3
Details	binding site for residue CA B 101

Chain	Residue
B	HOH208
B	HOH213
B	HOH215

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:22431598, ECO:0000269|PubMed:22566140

Chain	Residue	Details
A	GLY10
A	VAL29
A	ALA59
A	ASN116

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: N-acetylmethionine; in GTPase KRas; alternate => ECO:0000269|Ref.17

Chain	Residue	Details
A	MET1

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: N-acetylthreonine; in GTPase KRas, N-terminally processed => ECO:0000269|Ref.17

Chain	Residue	Details
A	THR2

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	MOD_RES: N6-acetyllysine => ECO:0000269|PubMed:22711838

Chain	Residue	Details
A	LYS104

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	CARBOHYD: (Microbial infection) O-linked (Glc) threonine; by P.sordellii toxin TcsL => ECO:0000269|PubMed:19744486

Chain	Residue	Details
A	THR35

---