5UFE
Wild-type K-Ras(GNP)/R11.1.6 complex
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 31 |
| Details | binding site for residue GNP A 201 |
| Chain | Residue |
| A | GLY13 |
| A | ASP119 |
| A | LEU120 |
| A | SER145 |
| A | ALA146 |
| A | LYS147 |
| A | CD206 |
| A | CL208 |
| A | MG211 |
| A | HOH302 |
| A | HOH305 |
| A | VAL14 |
| A | HOH316 |
| A | HOH317 |
| A | HOH319 |
| A | HOH320 |
| A | HOH326 |
| A | HOH328 |
| A | HOH330 |
| A | HOH334 |
| A | HOH350 |
| B | ASP15 |
| A | GLY15 |
| B | LYS18 |
| B | HOH203 |
| A | LYS16 |
| A | SER17 |
| A | ALA18 |
| A | GLY60 |
| A | ASN116 |
| A | LYS117 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue CA A 202 |
| Chain | Residue |
| A | GLU31 |
| A | CL208 |
| A | HOH306 |
| A | HOH317 |
| A | HOH365 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue CA A 203 |
| Chain | Residue |
| A | ASP108 |
| A | HOH308 |
| A | HOH338 |
| A | HOH351 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue CD A 204 |
| Chain | Residue |
| A | GLU37 |
| A | GLU62 |
| A | HOH367 |
| B | LYS32 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue CD A 205 |
| Chain | Residue |
| A | HIS94 |
| A | GLU98 |
| A | CYS118 |
| A | CL209 |
| A | CO214 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue CD A 206 |
| Chain | Residue |
| A | ASP33 |
| A | GNP201 |
| A | HOH368 |
| B | ALA1 |
| B | HOH203 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue CD A 207 |
| Chain | Residue |
| A | GLU91 |
| A | ASP154 |
| A | HOH356 |
| A | HOH371 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue CL A 208 |
| Chain | Residue |
| A | GNP201 |
| A | CA202 |
| B | ASP15 |
| B | LYS18 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 209 |
| Chain | Residue |
| A | ASP119 |
| A | THR148 |
| A | CD205 |
| site_id | AD1 |
| Number of Residues | 5 |
| Details | binding site for residue CL A 210 |
| Chain | Residue |
| A | HIS95 |
| A | ARG123 |
| A | GLU143 |
| A | CO214 |
| A | HOH329 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for residue MG A 211 |
| Chain | Residue |
| A | SER17 |
| A | GNP201 |
| A | HOH305 |
| A | HOH319 |
| A | HOH326 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for residue CO A 212 |
| Chain | Residue |
| A | GLU3 |
| A | GLU76 |
| A | HOH336 |
| A | HOH341 |
| B | GLU11 |
| B | HOH201 |
| site_id | AD4 |
| Number of Residues | 4 |
| Details | binding site for residue CO A 213 |
| Chain | Residue |
| A | HIS27 |
| A | ASP105 |
| A | HOH304 |
| A | HOH331 |
| site_id | AD5 |
| Number of Residues | 8 |
| Details | binding site for residue CO A 214 |
| Chain | Residue |
| A | HIS95 |
| A | GLU98 |
| A | CYS118 |
| A | GLU143 |
| A | CD205 |
| A | CL210 |
| A | HOH310 |
| A | HOH329 |
| site_id | AD6 |
| Number of Residues | 3 |
| Details | binding site for residue CA B 101 |
| Chain | Residue |
| B | HOH208 |
| B | HOH213 |
| B | HOH215 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | Motif: {"description":"Effector region"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 18 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"22431598","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22566140","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"34380736","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"35522713","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"N-acetylmethionine; in GTPase KRas; alternate","evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"FEB-2008","submissionDatabase":"UniProtKB","authors":["Bienvenut W.V.","Calvo F.","Kolch W."]}}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"N-acetylthreonine; in GTPase KRas, N-terminally processed","evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"FEB-2008","submissionDatabase":"UniProtKB","authors":["Bienvenut W.V.","Calvo F.","Kolch W."]}}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"22711838","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"(Microbial infection) O-linked (Glc) threonine; by P.sordellii toxin TcsL","evidences":[{"source":"PubMed","id":"19744486","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
