5UCT

Mycobacterium tuberculosis toxin MazF-mt6

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0004518	molecular_function	nuclease activity
A	0004519	molecular_function	endonuclease activity
A	0004521	molecular_function	RNA endonuclease activity
A	0005515	molecular_function	protein binding
A	0006402	biological_process	mRNA catabolic process
A	0016075	biological_process	rRNA catabolic process
A	0016787	molecular_function	hydrolase activity
A	0017148	biological_process	negative regulation of translation
A	0044003	biological_process	symbiont-mediated perturbation of host process
A	0045892	biological_process	negative regulation of DNA-templated transcription
A	0045926	biological_process	negative regulation of growth
A	0045927	biological_process	positive regulation of growth
B	0003677	molecular_function	DNA binding
B	0004518	molecular_function	nuclease activity
B	0004519	molecular_function	endonuclease activity
B	0004521	molecular_function	RNA endonuclease activity
B	0005515	molecular_function	protein binding
B	0006402	biological_process	mRNA catabolic process
B	0016075	biological_process	rRNA catabolic process
B	0016787	molecular_function	hydrolase activity
B	0017148	biological_process	negative regulation of translation
B	0044003	biological_process	symbiont-mediated perturbation of host process
B	0045892	biological_process	negative regulation of DNA-templated transcription
B	0045926	biological_process	negative regulation of growth
B	0045927	biological_process	positive regulation of growth

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	binding site for residue SO4 A 201

Chain	Residue
A	THR36
A	THR38
A	HOH303

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site_id	AC2
Number of Residues	5
Details	binding site for residue SO4 B 201

Chain	Residue
B	ARG13
B	THR36
B	THR37
B	THR38
B	HOH307

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