5U7A
Crystal structure of a complex formed between MerB and Dimethyltin
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016829 | molecular_function | lyase activity |
| A | 0018836 | molecular_function | alkylmercury lyase activity |
| A | 0046689 | biological_process | response to mercury ion |
| B | 0016829 | molecular_function | lyase activity |
| B | 0018836 | molecular_function | alkylmercury lyase activity |
| B | 0046689 | biological_process | response to mercury ion |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue ZN5 A 301 |
| Chain | Residue |
| A | CYS96 |
| A | ASP99 |
| A | HOH457 |
| A | HOH524 |
| A | HOH529 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | binding site for residue BR A 302 |
| Chain | Residue |
| A | PRO5 |
| B | HOH479 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | binding site for residue PO4 A 303 |
| Chain | Residue |
| A | HIS163 |
| A | TRP174 |
| A | HIS178 |
| A | HOH447 |
| A | HOH454 |
| B | TRP174 |
| B | HIS178 |
| B | HOH453 |
| A | CYS160 |
| A | HIS161 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue ZN5 B 301 |
| Chain | Residue |
| B | ASP99 |
| B | HOH407 |
| B | HOH488 |
| B | HOH499 |
| B | HOH522 |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 3 |
| Details | M-CSA 297 |
| Chain | Residue | Details |
| A | CYS96 | activator, covalently attached, hydrogen bond donor, nucleophile, proton donor |
| A | ASP99 | activator, hydrogen bond acceptor, hydrogen bond donor, increase nucleophilicity, promote heterolysis, proton acceptor, proton donor |
| A | CYS159 | activator, covalently attached, nucleophile, proton donor |
| site_id | MCSA2 |
| Number of Residues | 3 |
| Details | M-CSA 297 |
| Chain | Residue | Details |
| B | CYS96 | activator, covalently attached, hydrogen bond donor, nucleophile, proton donor |
| B | ASP99 | activator, hydrogen bond acceptor, hydrogen bond donor, increase nucleophilicity, promote heterolysis, proton acceptor, proton donor |
| B | CYS159 | activator, covalently attached, nucleophile, proton donor |
