5U76
Chicken Slo2.2 in a closed conformation vitrified in the presence of 300 mM NaCl
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005228 | molecular_function | intracellular sodium-activated potassium channel activity |
| A | 0005267 | molecular_function | potassium channel activity |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006813 | biological_process | potassium ion transport |
| A | 0015271 | molecular_function | outward rectifier potassium channel activity |
| A | 0016020 | cellular_component | membrane |
| A | 0051289 | biological_process | protein homotetramerization |
| A | 0071805 | biological_process | potassium ion transmembrane transport |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1005 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000255 |
| Chain | Residue | Details |
| A | MET1-ARG95 | |
| A | TYR175-GLN185 | |
| A | LYS225-GLN249 | |
| A | GLN324-LEU1201 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 20 |
| Details | TRANSMEM: Helical; Name=Segment S1 => ECO:0000255 |
| Chain | Residue | Details |
| A | LEU96-ASP116 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 49 |
| Details | TOPO_DOM: Extracellular => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN117-LEU153 | |
| A | TRP207-ARG211 | |
| A | LEU271-SER279 | |
| A | PRO301-LYS302 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 20 |
| Details | TRANSMEM: Helical; Name=Segment S2 => ECO:0000255 |
| Chain | Residue | Details |
| A | PRO154-ILE174 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 20 |
| Details | TRANSMEM: Helical; Name=Segment S3 => ECO:0000255 |
| Chain | Residue | Details |
| A | ILE186-PHE206 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 12 |
| Details | TRANSMEM: Helical; Name=Segment S4 => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN212-ALA224 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 20 |
| Details | TRANSMEM: Helical; Name=Segment S5 => ECO:0000255 |
| Chain | Residue | Details |
| A | VAL250-HIS270 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 20 |
| Details | INTRAMEM: Pore-forming => ECO:0000255 |
| Chain | Residue | Details |
| A | LEU280-THR300 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 20 |
| Details | TRANSMEM: Helical; Name=Segment S6 => ECO:0000255 |
| Chain | Residue | Details |
| A | ILE303-LEU323 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN131 | |
| A | ASN136 |
