5U70
Chicken Slo2.2 in an open conformation vitrified in the presence of 300 mM NaCl
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005228 | molecular_function | intracellular sodium-activated potassium channel activity |
| A | 0005267 | molecular_function | potassium channel activity |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006811 | biological_process | monoatomic ion transport |
| A | 0006813 | biological_process | potassium ion transport |
| A | 0015271 | molecular_function | outward rectifier potassium channel activity |
| A | 0016020 | cellular_component | membrane |
| A | 0034220 | biological_process | monoatomic ion transmembrane transport |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051289 | biological_process | protein homotetramerization |
| A | 0071805 | biological_process | potassium ion transmembrane transport |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 22 |
| Details | Transmembrane: {"description":"Helical; Name=Segment S1","evidences":[{"source":"PubMed","id":"28111072","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5U70","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 22 |
| Details | Transmembrane: {"description":"Helical; Name=Segment S2","evidences":[{"source":"PubMed","id":"28111072","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5U70","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 27 |
| Details | Topological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 21 |
| Details | Transmembrane: {"description":"Helical; Name=Segment S3","evidences":[{"source":"PubMed","id":"28111072","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5U70","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 18 |
| Details | Topological domain: {"description":"Extracellular","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 12 |
| Details | Transmembrane: {"description":"Helical; Name=Segment S4","evidences":[{"source":"PubMed","id":"28111072","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5U70","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 22 |
| Details | Transmembrane: {"description":"Helical; Name=Segment S5","evidences":[{"source":"PubMed","id":"28111072","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5U70","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 20 |
| Details | Intramembrane: {"description":"Pore-forming"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 21 |
| Details | Transmembrane: {"description":"Helical; Name=Segment S6","evidences":[{"source":"PubMed","id":"28111072","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5U70","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 136 |
| Details | Domain: {"description":"RCK N-terminal 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00543","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 140 |
| Details | Domain: {"description":"RCK N-terminal 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00543","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI12 |
| Number of Residues | 21 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"Q5JUK3","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
