5U39

Pseudomonas aeruginosa LpxC in complex with CHIR-090

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006796	biological_process	phosphate-containing compound metabolic process
A	0008759	molecular_function	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
A	0009245	biological_process	lipid A biosynthetic process
A	0016787	molecular_function	hydrolase activity
A	0019637	biological_process	organophosphate metabolic process
A	0046872	molecular_function	metal ion binding
A	0103117	molecular_function	UDP-3-O-acyl-N-acetylglucosamine deacetylase activity
A	1901135	biological_process	carbohydrate derivative metabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ZN A 501

Chain	Residue
A	HIS78
A	HIS237
A	ASP241
A	C90502

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site_id	AC2
Number of Residues	20
Details	binding site for residue C90 A 502

Chain	Residue
A	ILE197
A	LEU200
A	ARG201
A	GLY209
A	SER210
A	VAL216
A	LEU223
A	HIS237
A	LYS238
A	ASP241
A	HIS264
A	ZN501
A	HOH619
A	HOH687
A	HOH742
A	GLU77
A	HIS78
A	THR190
A	PHE191
A	MET194

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton donor => ECO:0000255|HAMAP-Rule:MF_00388

Chain	Residue	Details
A	HIS264

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site_id	SWS_FT_FI2
Number of Residues	3
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00388

Chain	Residue	Details
A	HIS78
A	HIS237
A	ASP241

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