5U0C
Structure of Zika virus NS5 RNA polymerase domain
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003968 | molecular_function | RNA-directed RNA polymerase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0039694 | biological_process | viral RNA genome replication |
| B | 0003968 | molecular_function | RNA-directed RNA polymerase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0039694 | biological_process | viral RNA genome replication |
| C | 0003968 | molecular_function | RNA-directed RNA polymerase activity |
| C | 0005524 | molecular_function | ATP binding |
| C | 0039694 | biological_process | viral RNA genome replication |
| D | 0003968 | molecular_function | RNA-directed RNA polymerase activity |
| D | 0005524 | molecular_function | ATP binding |
| D | 0039694 | biological_process | viral RNA genome replication |
| E | 0003968 | molecular_function | RNA-directed RNA polymerase activity |
| E | 0005524 | molecular_function | ATP binding |
| E | 0039694 | biological_process | viral RNA genome replication |
| F | 0003968 | molecular_function | RNA-directed RNA polymerase activity |
| F | 0005524 | molecular_function | ATP binding |
| F | 0039694 | biological_process | viral RNA genome replication |
| G | 0003968 | molecular_function | RNA-directed RNA polymerase activity |
| G | 0005524 | molecular_function | ATP binding |
| G | 0039694 | biological_process | viral RNA genome replication |
| H | 0003968 | molecular_function | RNA-directed RNA polymerase activity |
| H | 0005524 | molecular_function | ATP binding |
| H | 0039694 | biological_process | viral RNA genome replication |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 1001 |
| Chain | Residue |
| A | GLU439 |
| A | HIS443 |
| A | CYS448 |
| A | CYS451 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue ZN A 1002 |
| Chain | Residue |
| A | HIS714 |
| A | CYS730 |
| A | CYS849 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 1001 |
| Chain | Residue |
| B | CYS448 |
| B | CYS451 |
| B | GLU439 |
| B | HIS443 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue ZN B 1002 |
| Chain | Residue |
| B | HIS714 |
| B | CYS730 |
| B | CYS849 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue ZN C 1001 |
| Chain | Residue |
| C | GLU439 |
| C | HIS443 |
| C | CYS448 |
| C | CYS451 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue ZN C 1002 |
| Chain | Residue |
| C | HIS714 |
| C | ASN716 |
| C | CYS730 |
| C | CYS849 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue ZN D 1001 |
| Chain | Residue |
| D | GLU439 |
| D | HIS443 |
| D | CYS448 |
| D | CYS451 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | binding site for residue ZN D 1002 |
| Chain | Residue |
| D | HIS714 |
| D | CYS730 |
| D | CYS849 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue ZN E 1001 |
| Chain | Residue |
| E | GLU439 |
| E | HIS443 |
| E | CYS448 |
| E | CYS451 |
| site_id | AD1 |
| Number of Residues | 3 |
| Details | binding site for residue ZN E 1002 |
| Chain | Residue |
| E | HIS714 |
| E | CYS730 |
| E | CYS849 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue ZN F 1001 |
| Chain | Residue |
| F | GLU439 |
| F | HIS443 |
| F | CYS448 |
| F | CYS451 |
| site_id | AD3 |
| Number of Residues | 3 |
| Details | binding site for residue ZN F 1002 |
| Chain | Residue |
| F | HIS714 |
| F | CYS730 |
| F | CYS849 |
| site_id | AD4 |
| Number of Residues | 4 |
| Details | binding site for residue ZN G 1001 |
| Chain | Residue |
| G | GLU439 |
| G | HIS443 |
| G | CYS448 |
| G | CYS451 |
| site_id | AD5 |
| Number of Residues | 3 |
| Details | binding site for residue ZN G 1002 |
| Chain | Residue |
| G | HIS714 |
| G | CYS730 |
| G | CYS849 |
| site_id | AD6 |
| Number of Residues | 4 |
| Details | binding site for residue ZN H 1001 |
| Chain | Residue |
| H | GLU439 |
| H | HIS443 |
| H | CYS448 |
| H | CYS451 |
| site_id | AD7 |
| Number of Residues | 3 |
| Details | binding site for residue ZN H 1002 |
| Chain | Residue |
| H | HIS714 |
| H | CYS730 |
| H | CYS849 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 56 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:28291746, ECO:0000269|PubMed:28345596, ECO:0000269|PubMed:28345656 |
| Chain | Residue | Details |
| A | GLU439 | |
| B | CYS448 | |
| B | CYS451 | |
| B | HIS714 | |
| B | CYS730 | |
| B | CYS849 | |
| C | GLU439 | |
| C | HIS443 | |
| C | CYS448 | |
| C | CYS451 | |
| C | HIS714 | |
| A | HIS443 | |
| C | CYS730 | |
| C | CYS849 | |
| D | GLU439 | |
| D | HIS443 | |
| D | CYS448 | |
| D | CYS451 | |
| D | HIS714 | |
| D | CYS730 | |
| D | CYS849 | |
| E | GLU439 | |
| A | CYS448 | |
| E | HIS443 | |
| E | CYS448 | |
| E | CYS451 | |
| E | HIS714 | |
| E | CYS730 | |
| E | CYS849 | |
| F | GLU439 | |
| F | HIS443 | |
| F | CYS448 | |
| F | CYS451 | |
| A | CYS451 | |
| F | HIS714 | |
| F | CYS730 | |
| F | CYS849 | |
| G | GLU439 | |
| G | HIS443 | |
| G | CYS448 | |
| G | CYS451 | |
| G | HIS714 | |
| G | CYS730 | |
| G | CYS849 | |
| A | HIS714 | |
| H | GLU439 | |
| H | HIS443 | |
| H | CYS448 | |
| H | CYS451 | |
| H | HIS714 | |
| H | CYS730 | |
| H | CYS849 | |
| A | CYS730 | |
| A | CYS849 | |
| B | GLU439 | |
| B | HIS443 |
