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5TYX

DNA Polymerase Mu Product Complex, Mn2+ (15 min)

Functional Information from GO Data
ChainGOidnamespacecontents
A0003677molecular_functionDNA binding
A0003887molecular_functionDNA-directed DNA polymerase activity
A0005634cellular_componentnucleus
A0006281biological_processDNA repair
A0016779molecular_functionnucleotidyltransferase activity
A0034061molecular_functionDNA polymerase activity
Functional Information from PDB Data
site_idAC1
Number of Residues17
Detailsbinding site for residue PPV A 701
ChainResidue
AGLY319
AHOH810
AHOH898
AHOH909
AHOH910
AHOH964
AHOH994
PDT5
PMN101
AGLY320
AARG323
ALYS325
AGLY328
AHIS329
AASP330
AASP332
AMN703

site_idAC2
Number of Residues7
Detailsbinding site for residue MN A 702
ChainResidue
AASP330
AASP332
AASP418
AMN703
PDA4
PDT5
PHOH210

site_idAC3
Number of Residues6
Detailsbinding site for residue MN A 703
ChainResidue
AASP330
AASP332
APPV701
AMN702
AHOH909
PDT5

site_idAC4
Number of Residues2
Detailsbinding site for residue MN A 704
ChainResidue
AGLU218
AHIS219

site_idAC5
Number of Residues2
Detailsbinding site for residue MN A 705
ChainResidue
AHIS208
DDG1

site_idAC6
Number of Residues5
Detailsbinding site for residue MN A 706
ChainResidue
AGLU386
AHIS459
AHOH1005
AHOH1027
THOH201

site_idAC7
Number of Residues6
Detailsbinding site for residue NA A 707
ChainResidue
ATHR241
AILE243
AVAL246
AHOH1021
PDT3
PHOH214

site_idAC8
Number of Residues4
Detailsbinding site for residue EDO A 708
ChainResidue
APRO190
ASER191
APRO192
AGLN198

site_idAC9
Number of Residues5
Detailsbinding site for residue EDO A 709
ChainResidue
ATHR314
ATHR336
APHE427
AHOH830
AHOH975

site_idAD1
Number of Residues4
Detailsbinding site for residue EPE A 710
ChainResidue
ALYS325
ALEU326
AGLN327
AHOH838

site_idAD2
Number of Residues4
Detailsbinding site for residue MN T 101
ChainResidue
TDG2
THOH222
THOH227
THOH235

site_idAD3
Number of Residues5
Detailsbinding site for residue MN P 101
ChainResidue
APPV701
AHOH964
AHOH994
PDT5
PHOH215

site_idAD4
Number of Residues7
Detailsbinding site for residue EDO P 102
ChainResidue
AARG387
AGLY433
ATRP434
AARG445
PDA4
PDT5
PHOH212

Functional Information from PROSITE/UniProt
site_idPS00522
Number of Residues20
DetailsDNA_POLYMERASE_X DNA polymerase family X signature. GGFrRGklqGhDVDFLIthP
ChainResidueDetails
AGLY319-PRO338

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues3
DetailsBINDING: BINDING => ECO:0000250
ChainResidueDetails
AASP330
AASP332
AALA430

site_idSWS_FT_FI2
Number of Residues1
DetailsSITE: Responsible for the low discrimination between dNTP and rNTP
ChainResidueDetails
AARG445

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PDB entries from 2024-11-06

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