Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003887 | molecular_function | DNA-directed DNA polymerase activity |
| A | 0005634 | cellular_component | nucleus |
| A | 0006281 | biological_process | DNA repair |
| A | 0016779 | molecular_function | nucleotidyltransferase activity |
| A | 0034061 | molecular_function | DNA polymerase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 30 |
| Details | binding site for residue TTP A 501 |
| Chain | Residue |
| A | GLY319 |
| A | TRP434 |
| A | THR435 |
| A | GLY436 |
| A | LYS438 |
| A | MN502 |
| A | MN503 |
| A | CA506 |
| A | PPV507 |
| A | HOH611 |
| A | HOH625 |
| A | GLY320 |
| A | HOH664 |
| A | HOH677 |
| A | HOH696 |
| A | HOH718 |
| P | DA4 |
| P | DT5 |
| P | MN101 |
| P | EDO102 |
| P | HOH202 |
| P | HOH212 |
| A | ARG323 |
| T | DA5 |
| A | LYS325 |
| A | GLY328 |
| A | HIS329 |
| A | ASP330 |
| A | ASP332 |
| A | GLY433 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue MN A 502 |
| Chain | Residue |
| A | ASP330 |
| A | ASP332 |
| A | ASP418 |
| A | TTP501 |
| A | MN503 |
| P | DA4 |
| P | DT5 |
| P | HOH202 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | binding site for residue MN A 503 |
| Chain | Residue |
| A | ASP330 |
| A | ASP332 |
| A | TTP501 |
| A | MN502 |
| A | CA506 |
| A | PPV507 |
| A | HOH718 |
| P | DT5 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue MN A 504 |
| Chain | Residue |
| A | GLU218 |
| A | HIS219 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue NA A 505 |
| Chain | Residue |
| A | THR241 |
| A | ILE243 |
| A | VAL246 |
| A | HOH773 |
| P | DT3 |
| P | HOH203 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | binding site for residue CA A 506 |
| Chain | Residue |
| A | ASP330 |
| A | ASP332 |
| A | ASP418 |
| A | TTP501 |
| A | MN503 |
| P | DA4 |
| P | DT5 |
| P | HOH202 |
| site_id | AC7 |
| Number of Residues | 18 |
| Details | binding site for residue PPV A 507 |
| Chain | Residue |
| A | GLY319 |
| A | GLY320 |
| A | ARG323 |
| A | LYS325 |
| A | GLY328 |
| A | HIS329 |
| A | ASP330 |
| A | ASP332 |
| A | TTP501 |
| A | MN503 |
| A | HOH611 |
| A | HOH625 |
| A | HOH664 |
| A | HOH677 |
| A | HOH696 |
| A | HOH718 |
| P | DT5 |
| P | MN101 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | binding site for residue DTT A 508 |
| Chain | Residue |
| A | CYS180 |
| A | HOH760 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 509 |
| Chain | Residue |
| A | ARG253 |
| A | ARG256 |
| A | GLU451 |
| A | LYS452 |
| A | GLY453 |
| A | HOH619 |
| A | HOH673 |
| site_id | AD1 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 510 |
| Chain | Residue |
| A | HIS152 |
| A | THR314 |
| A | THR336 |
| A | HOH667 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for residue EPE A 511 |
| Chain | Residue |
| A | LEU149 |
| A | LYS325 |
| A | LEU326 |
| A | GLN327 |
| A | HOH710 |
| site_id | AD3 |
| Number of Residues | 5 |
| Details | binding site for residue MN P 101 |
| Chain | Residue |
| A | TTP501 |
| A | PPV507 |
| P | DT5 |
| P | HOH212 |
| A | HIS329 |
| site_id | AD4 |
| Number of Residues | 7 |
| Details | binding site for residue EDO P 102 |
| Chain | Residue |
| A | ARG387 |
| A | GLY433 |
| A | TRP434 |
| A | ARG445 |
| A | TTP501 |
| P | DA4 |
| P | DT5 |
Functional Information from PROSITE/UniProt
| site_id | PS00522 |
| Number of Residues | 20 |
| Details | DNA_POLYMERASE_X DNA polymerase family X signature. GGFrRGklqGhDVDFLIthP |
| Chain | Residue | Details |
| A | GLY319-PRO338 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| A | ASP330 | |
| A | ASP332 | |
| A | ALA430 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | SITE: Responsible for the low discrimination between dNTP and rNTP |
| Chain | Residue | Details |
| A | ARG445 | |
