5TVM

Crystal structure of Trypanosoma brucei AdoMetDC/prozyme heterodimer

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004014	molecular_function	adenosylmethionine decarboxylase activity
A	0008295	biological_process	spermidine biosynthetic process
B	0004014	molecular_function	adenosylmethionine decarboxylase activity
B	0008295	biological_process	spermidine biosynthetic process
C	0004014	molecular_function	adenosylmethionine decarboxylase activity
C	0008295	biological_process	spermidine biosynthetic process
D	0004014	molecular_function	adenosylmethionine decarboxylase activity
D	0008295	biological_process	spermidine biosynthetic process
E	0004014	molecular_function	adenosylmethionine decarboxylase activity
E	0005829	cellular_component	cytosol
E	0006597	biological_process	spermine biosynthetic process
E	0008295	biological_process	spermidine biosynthetic process
E	0016829	molecular_function	lyase activity
F	0004014	molecular_function	adenosylmethionine decarboxylase activity
F	0005829	cellular_component	cytosol
F	0006597	biological_process	spermine biosynthetic process
F	0008295	biological_process	spermidine biosynthetic process
F	0016829	molecular_function	lyase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	12
Details	binding site for residue B3P B 401

Chain	Residue
A	GLU36
B	ASP306
B	TYR341
B	HOH518
A	ILE38
B	ARG94
B	GLU124
B	TRP125
B	SER187
B	ASP189
B	ALA190
B	PHE304

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site_id	AC2
Number of Residues	10
Details	binding site for residue B3P D 401

Chain	Residue
C	GLU36
D	ARG94
D	GLU124
D	TRP125
D	SER187
D	ASP189
D	GLN191
D	PHE304
D	ASP306
D	TYR341

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site_id	AC3
Number of Residues	6
Details	binding site for residue PUT E 401

Chain	Residue
E	GLU42
E	ASN44
E	TRP126
E	GLU193
E	ASP195
E	ASP282

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site_id	AC4
Number of Residues	8
Details	binding site for residue PUT F 401

Chain	Residue
F	GLU42
F	ASN44
F	TRP126
F	GLU193
F	ASP195
F	ASP282
F	TYR314
F	HOH507

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