5TOS
Botrytis-induced kinase 1 (BIK1) from Arabidopsis thaliana
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0002221 | biological_process | pattern recognition receptor signaling pathway |
| A | 0002237 | biological_process | response to molecule of bacterial origin |
| A | 0002376 | biological_process | immune system process |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0004674 | molecular_function | protein serine/threonine kinase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005730 | cellular_component | nucleolus |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005768 | cellular_component | endosome |
| A | 0005794 | cellular_component | Golgi apparatus |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006468 | biological_process | protein phosphorylation |
| A | 0006952 | biological_process | defense response |
| A | 0009620 | biological_process | response to fungus |
| A | 0010008 | cellular_component | endosome membrane |
| A | 0010119 | biological_process | regulation of stomatal movement |
| A | 0012505 | cellular_component | endomembrane system |
| A | 0016301 | molecular_function | kinase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0042742 | biological_process | defense response to bacterium |
| A | 0045087 | biological_process | innate immune response |
| A | 0050832 | biological_process | defense response to fungus |
| A | 0080141 | biological_process | regulation of jasmonic acid biosynthetic process |
| A | 0080142 | biological_process | regulation of salicylic acid biosynthetic process |
| A | 0106310 | molecular_function | protein serine kinase activity |
| A | 1900424 | biological_process | regulation of defense response to bacterium |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0002221 | biological_process | pattern recognition receptor signaling pathway |
| B | 0002237 | biological_process | response to molecule of bacterial origin |
| B | 0002376 | biological_process | immune system process |
| B | 0004672 | molecular_function | protein kinase activity |
| B | 0004674 | molecular_function | protein serine/threonine kinase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005634 | cellular_component | nucleus |
| B | 0005730 | cellular_component | nucleolus |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005768 | cellular_component | endosome |
| B | 0005794 | cellular_component | Golgi apparatus |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0006468 | biological_process | protein phosphorylation |
| B | 0006952 | biological_process | defense response |
| B | 0009620 | biological_process | response to fungus |
| B | 0010008 | cellular_component | endosome membrane |
| B | 0010119 | biological_process | regulation of stomatal movement |
| B | 0012505 | cellular_component | endomembrane system |
| B | 0016301 | molecular_function | kinase activity |
| B | 0016740 | molecular_function | transferase activity |
| B | 0042742 | biological_process | defense response to bacterium |
| B | 0045087 | biological_process | innate immune response |
| B | 0050832 | biological_process | defense response to fungus |
| B | 0080141 | biological_process | regulation of jasmonic acid biosynthetic process |
| B | 0080142 | biological_process | regulation of salicylic acid biosynthetic process |
| B | 0106310 | molecular_function | protein serine kinase activity |
| B | 1900424 | biological_process | regulation of defense response to bacterium |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 34 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. IGEGGFGCVFkGwldestltptkpgtglviAVKK |
| Chain | Residue | Details |
| A | ILE73-LYS106 |
| site_id | PS00108 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. ViYrDIKasNILL |
| Chain | Residue | Details |
| A | VAL198-LEU210 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Motif: {"description":"Required for physical interaction with and phosphorylation of downstream signaling proteins (e.g. WRKY33, WRKY50, WRKY51 and WRKY57) to activate EFR-mediated immune signaling","evidences":[{"source":"PubMed","id":"29649442","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine; by autocatalysis","evidences":[{"source":"PubMed","id":"24104392","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30212650","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"Phosphothreonine; by autocatalysis","evidences":[{"source":"PubMed","id":"24104392","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30212650","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"30212650","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"Phosphoserine; by EFR","evidences":[{"source":"PubMed","id":"29649442","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphothreonine; by EFR","evidences":[{"source":"PubMed","id":"29649442","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphothreonine; by EFR","evidences":[{"source":"PubMed","id":"29649442","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30212650","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"24532660","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphotyrosine; by autocatalysis","evidences":[{"source":"PubMed","id":"24104392","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30212650","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI12 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"30212650","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI13 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine; by autocatalysis and BAK1","evidences":[{"source":"PubMed","id":"24104392","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30212650","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI14 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphotyrosine; by autocatalysis","evidences":[{"source":"PubMed","id":"24104392","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI15 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphotyrosine; by autocatalysis","evidences":[{"source":"PubMed","id":"24104392","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24532660","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI16 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"Phosphoserine; by autocatalysis","evidences":[{"source":"PubMed","id":"24104392","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI17 |
| Number of Residues | 12 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"32404997","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
