Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0008839 | molecular_function | 4-hydroxy-tetrahydrodipicolinate reductase |
| A | 0009085 | biological_process | lysine biosynthetic process |
| A | 0009089 | biological_process | lysine biosynthetic process via diaminopimelate |
| A | 0009274 | cellular_component | peptidoglycan-based cell wall |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016726 | molecular_function | oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor |
| A | 0019877 | biological_process | diaminopimelate biosynthetic process |
| A | 0050661 | molecular_function | NADP binding |
| A | 0051287 | molecular_function | NAD binding |
| A | 0070402 | molecular_function | NADPH binding |
| A | 0070404 | molecular_function | NADH binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | binding site for residue PDC A 301 |
| Chain | Residue |
| A | THR77 |
| A | PHE217 |
| A | NAP304 |
| A | HOH424 |
| A | HOH447 |
| A | PRO103 |
| A | ASN104 |
| A | HIS133 |
| A | LYS136 |
| A | SER141 |
| A | GLY142 |
| A | THR143 |
| A | ALA192 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue BEZ A 302 |
| Chain | Residue |
| A | MET59 |
| A | MET59 |
| A | ARG83 |
| A | ARG83 |
| A | IMD303 |
| A | IMD303 |
| A | HOH494 |
| A | HOH494 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | binding site for residue IMD A 303 |
| Chain | Residue |
| A | MET59 |
| A | MET59 |
| A | GLY60 |
| A | GLY60 |
| A | GLU63 |
| A | GLU63 |
| A | TRP90 |
| A | TRP90 |
| A | BEZ302 |
| A | BEZ302 |
| site_id | AC4 |
| Number of Residues | 37 |
| Details | binding site for residue NAP A 304 |
| Chain | Residue |
| A | GLY7 |
| A | LYS9 |
| A | GLY10 |
| A | LYS11 |
| A | VAL12 |
| A | LEU32 |
| A | ASP33 |
| A | ALA34 |
| A | PHE52 |
| A | THR53 |
| A | GLY75 |
| A | THR76 |
| A | THR77 |
| A | ALA102 |
| A | PRO103 |
| A | ASN104 |
| A | PHE105 |
| A | LYS136 |
| A | PHE217 |
| A | PDC301 |
| A | EDO307 |
| A | HOH402 |
| A | HOH416 |
| A | HOH421 |
| A | HOH424 |
| A | HOH440 |
| A | HOH447 |
| A | HOH449 |
| A | HOH459 |
| A | HOH480 |
| A | HOH484 |
| A | HOH491 |
| A | HOH518 |
| A | HOH522 |
| A | HOH523 |
| A | HOH563 |
| A | HOH566 |
| site_id | AC5 |
| Number of Residues | 9 |
| Details | binding site for residue AE3 A 305 |
| Chain | Residue |
| A | ILE129 |
| A | LEU131 |
| A | LEU190 |
| A | GLU195 |
| A | GLU195 |
| A | THR204 |
| A | ARG208 |
| A | ASP210 |
| A | HOH429 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue CL A 306 |
| Chain | Residue |
| A | ARG146 |
| A | LEU238 |
| A | GLU239 |
| A | HOH479 |
| site_id | AC7 |
| Number of Residues | 9 |
| Details | binding site for residue EDO A 307 |
| Chain | Residue |
| A | THR53 |
| A | HIS54 |
| A | HIS135 |
| A | LYS136 |
| A | ALA137 |
| A | NAP304 |
| A | EDO308 |
| A | HOH447 |
| A | HOH459 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 308 |
| Chain | Residue |
| A | HIS54 |
| A | HIS135 |
| A | EDO307 |
| A | HOH416 |
| A | HOH425 |
| A | HOH454 |
| A | HOH468 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 309 |
| Chain | Residue |
| A | HOH487 |
| A | HOH497 |
| A | HOH602 |
| A | GLU63 |
| A | PHE64 |
| site_id | AD1 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 310 |
| Chain | Residue |
| A | GLY69 |
| A | ASN96 |
| A | THR97 |
| A | HOH668 |
| site_id | AD2 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 311 |
| Chain | Residue |
| A | ASP138 |
| A | ALA139 |
| A | PRO140 |
| A | THR167 |
| A | HOH446 |
| A | HOH499 |
| A | HOH610 |
| site_id | AD3 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 312 |
| Chain | Residue |
| A | ASN161 |
| A | HOH413 |
| site_id | AD4 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 313 |
| Chain | Residue |
| A | SO4315 |
| A | HOH401 |
| A | HOH510 |
| site_id | AD5 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 314 |
| Chain | Residue |
| A | PHE122 |
| A | ASP124 |
| site_id | AD6 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 315 |
| Chain | Residue |
| A | LEU223 |
| A | EDO313 |
| A | HOH590 |
| A | HOH591 |
| site_id | AD7 |
| Number of Residues | 4 |
| Details | binding site for residue CL A 316 |
| Chain | Residue |
| A | LYS94 |
| A | PRO95 |
| A | ASN96 |
| A | THR97 |
| site_id | AD8 |
| Number of Residues | 2 |
| Details | binding site for residue CL A 317 |
| Chain | Residue |
| A | ALA81 |
| A | LYS149 |
| site_id | AD9 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 318 |
| Chain | Residue |
| A | ASP56 |
| A | VAL57 |
| A | HOH411 |
| A | HOH454 |
| A | HOH493 |
| A | HOH522 |
| A | HOH523 |
Functional Information from PROSITE/UniProt
| site_id | PS01298 |
| Number of Residues | 18 |
| Details | DAPB Dihydrodipicolinate reductase signature. EViElHhphKaDapSGTA |
| Chain | Residue | Details |
| A | GLU127-ALA144 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | HIS132 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | ACT_SITE: Proton donor => ECO:0000305 |
| Chain | Residue | Details |
| A | LYS136 | |
| Chain | Residue | Details |
| A | GLY75 | |
| A | ALA102 | |
| A | LYS11 | |
| A | LYS136 | |
| Chain | Residue | Details |
| A | HIS133 | |
| A | GLY142 | |
| Chain | Residue | Details |
| A | ASP33 | |
