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5TJ7

Structure of WWP2 WW2-2,3-linker-HECT aa 334-398 linked to 485-865

Functional Information from GO Data
ChainGOidnamespacecontents
A0004842molecular_functionubiquitin-protein transferase activity
B0004842molecular_functionubiquitin-protein transferase activity
C0004842molecular_functionubiquitin-protein transferase activity
D0004842molecular_functionubiquitin-protein transferase activity
Functional Information from PDB Data
site_idAC1
Number of Residues5
Detailsbinding site for residue NA A 901
ChainResidue
ATYR587
ATHR799
AILE813
ATHR837
AASN840

site_idAC2
Number of Residues5
Detailsbinding site for residue NA B 901
ChainResidue
BASN840
BTYR587
BTHR799
BILE813
BTHR837

site_idAC3
Number of Residues1
Detailsbinding site for residue SCN C 900
ChainResidue
CASP341

site_idAC4
Number of Residues1
Detailsbinding site for residue CL D 900
ChainResidue
DTYR704

site_idAC5
Number of Residues5
Detailsbinding site for residue NA D 901
ChainResidue
DTYR587
DTHR799
DILE813
DTHR837
DASN840

site_idAC6
Number of Residues9
Detailsbinding site for Di-peptide GLY D 486 and PRO D 488
ChainResidue
ATYR369
AARG376
AGLN522
DGLN485
DSER487
DGLY489
DALA490
DARG496
DTRP497

Functional Information from PROSITE/UniProt
site_idPS01159
Number of Residues26
DetailsWW_DOMAIN_1 WW/rsp5/WWP domain signature. Wekrtdprgrf.YYvdhntrtTTWQRP
ChainResidueDetails
ATRP336-PRO361

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues4
DetailsACT_SITE: Glycyl thioester intermediate => ECO:0000255|PROSITE-ProRule:PRU00104
ChainResidueDetails
ACYS838
BCYS838
CCYS838
DCYS838

226707

PDB entries from 2024-10-30

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