5T8R
Crystal structure of human BAZ2A PHD zinc finger in complex with unmodified H3 10-mer
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 1801 |
| Chain | Residue |
| A | CYS1679 |
| A | CYS1682 |
| A | HIS1702 |
| A | CYS1705 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 1802 |
| Chain | Residue |
| A | CYS1694 |
| A | CYS1697 |
| A | CYS1720 |
| A | CYS1723 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue PO4 A 1803 |
| Chain | Residue |
| A | HOH1904 |
| A | HOH1912 |
| A | HOH1913 |
| A | HOH1917 |
| A | ARG1707 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 1801 |
| Chain | Residue |
| B | CYS1679 |
| B | CYS1682 |
| B | HIS1702 |
| B | CYS1705 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 1802 |
| Chain | Residue |
| B | CYS1694 |
| B | CYS1697 |
| B | CYS1720 |
| B | CYS1723 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | binding site for residue PO4 B 1803 |
| Chain | Residue |
| B | ARG1707 |
| B | HOH1910 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue ZN C 1801 |
| Chain | Residue |
| C | CYS1679 |
| C | CYS1682 |
| C | HIS1702 |
| C | CYS1705 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue ZN C 1802 |
| Chain | Residue |
| C | CYS1694 |
| C | CYS1697 |
| C | CYS1720 |
| C | CYS1723 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | binding site for residue GOL C 1803 |
| Chain | Residue |
| C | ARG1707 |
| C | HOH1920 |
| site_id | AD1 |
| Number of Residues | 4 |
| Details | binding site for residue ZN D 1801 |
| Chain | Residue |
| D | CYS1679 |
| D | CYS1682 |
| D | HIS1702 |
| D | CYS1705 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue ZN D 1802 |
| Chain | Residue |
| D | CYS1694 |
| D | CYS1697 |
| D | CYS1720 |
| D | CYS1723 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 200 |
| Details | Zinc finger: {"description":"PHD-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00146","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Citrulline; alternate","evidences":[{"source":"PubMed","id":"16567635","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphothreonine; by HASPIN and VRK1","evidences":[{"source":"PubMed","id":"15681610","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16185088","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31527692","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"N6-methyllysine; alternate","evidences":[{"source":"PubMed","id":"16267050","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16457588","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17194708","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"5-glutamyl serotonin; alternate","evidences":[{"source":"PubMed","id":"30867594","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphothreonine; by PKC","evidences":[{"source":"PubMed","id":"20228790","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Symmetric dimethylarginine; by PRMT5; alternate","evidences":[{"source":"UniProtKB","id":"P68433","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
