Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016301 | molecular_function | kinase activity |
| A | 0016303 | molecular_function | 1-phosphatidylinositol-3-kinase activity |
| A | 0043491 | biological_process | phosphatidylinositol 3-kinase/protein kinase B signal transduction |
| A | 0046854 | biological_process | phosphatidylinositol phosphate biosynthetic process |
| B | 0016301 | molecular_function | kinase activity |
| B | 0016303 | molecular_function | 1-phosphatidylinositol-3-kinase activity |
| B | 0043491 | biological_process | phosphatidylinositol 3-kinase/protein kinase B signal transduction |
| B | 0046854 | biological_process | phosphatidylinositol phosphate biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | binding site for residue 76C A 1101 |
| Chain | Residue |
| A | THR750 |
| A | VAL828 |
| A | SER831 |
| A | ASP832 |
| A | THR833 |
| A | MET900 |
| A | ILE910 |
| A | HOH1229 |
| A | PHE751 |
| A | MET752 |
| A | PRO758 |
| A | TRP760 |
| A | ILE777 |
| A | TYR813 |
| A | ILE825 |
| A | GLU826 |
| site_id | AC2 |
| Number of Residues | 16 |
| Details | binding site for residue 76C B 1101 |
| Chain | Residue |
| B | THR750 |
| B | PHE751 |
| B | MET752 |
| B | PRO758 |
| B | TRP760 |
| B | ILE777 |
| B | TYR813 |
| B | ILE825 |
| B | GLU826 |
| B | VAL828 |
| B | SER831 |
| B | ASP832 |
| B | THR833 |
| B | MET900 |
| B | ILE910 |
| B | HOH1222 |
Functional Information from PROSITE/UniProt
| site_id | PS00915 |
| Number of Residues | 15 |
| Details | PI3_4_KINASE_1 Phosphatidylinositol 3- and 4-kinases signature 1. FKng.DDLRQDmltlQ |
| Chain | Residue | Details |
| A | PHE778-GLN792 | |
| site_id | PS00916 |
| Number of Residues | 21 |
| Details | PI3_4_KINASE_2 Phosphatidylinositol 3- and 4-kinases signature 2. ScAgycVatYVLgIgDRHsdN |
| Chain | Residue | Details |
| A | SER878-ASN898 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | Region: {"description":"G-loop","evidences":[{"source":"PROSITE-ProRule","id":"PRU00269","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 16 |
| Details | Region: {"description":"Catalytic loop","evidences":[{"source":"PROSITE-ProRule","id":"PRU00269","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"O00329","evidenceCode":"ECO:0000250"}]} |
