5T77

Crystal structure of the MOP flippase MurJ

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005886	cellular_component	plasma membrane
A	0008360	biological_process	regulation of cell shape
A	0009252	biological_process	peptidoglycan biosynthetic process
A	0015648	molecular_function	lipid-linked peptidoglycan transporter activity
A	0015836	biological_process	lipid-linked peptidoglycan transport
A	0034204	biological_process	lipid translocation
A	0071555	biological_process	cell wall organization

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	binding site for residue CL A 501

Chain	Residue
A	TYR41
A	ARG255

---

site_id	AC2
Number of Residues	5
Details	binding site for residue CL A 502

Chain	Residue
A	LYS71
A	PHE79
A	HIS210
A	HIS213
A	ZN506

---

site_id	AC3
Number of Residues	3
Details	binding site for residue CL A 503

Chain	Residue
A	ZN506
A	HIS210
A	HIS213

---

site_id	AC4
Number of Residues	2
Details	binding site for residue CL A 504

Chain	Residue
A	SER72
A	GLY73

---

site_id	AC5
Number of Residues	3
Details	binding site for residue CL A 505

Chain	Residue
A	SER35
A	TYR36
A	LYS244

---

site_id	AC6
Number of Residues	4
Details	binding site for residue ZN A 506

Chain	Residue
A	HIS210
A	HIS213
A	CL502
A	CL503

---

site_id	AC7
Number of Residues	5
Details	binding site for residue CA A 507

Chain	Residue
A	GLU74
A	ASP77
A	HOH673
A	HOH682
A	HOH689

---

site_id	AC8
Number of Residues	6
Details	binding site for residue CA A 508

Chain	Residue
A	VAL34
A	HOH642
A	HOH678
A	HOH699
A	HOH724
A	HOH725

---

site_id	AC9
Number of Residues	7
Details	binding site for residue CA A 509

Chain	Residue
A	GLU318
A	OLC533
A	HOH625
A	HOH655
A	HOH702
A	HOH730
A	HOH732

---

site_id	AD1
Number of Residues	7
Details	binding site for residue NA A 510

Chain	Residue
A	PHE241
A	TYR242
A	HOH629
A	HOH670
A	HOH686
A	HOH739
A	HOH749

---

site_id	AD2
Number of Residues	5
Details	binding site for residue NA A 511

Chain	Residue
A	1PE514
A	HOH606
A	HOH634
A	HOH699
A	HOH724

---

site_id	AD3
Number of Residues	6
Details	binding site for residue 1PE A 512

Chain	Residue
A	TYR285
A	ASN288
A	ASP289
A	LYS292
A	ASP416
A	HOH728

---

site_id	AD4
Number of Residues	7
Details	binding site for residue 1PE A 513

Chain	Residue
A	LYS30
A	TYR31
A	PHE170
A	HIS319
A	GLY320
A	1PE514
A	HOH732

---

site_id	AD5
Number of Residues	6
Details	binding site for residue 1PE A 514

Chain	Residue
A	LYS30
A	ALA321
A	NA511
A	1PE513
A	HOH606
A	HOH656

---

site_id	AD6
Number of Residues	5
Details	binding site for residue OLB A 515

Chain	Residue
A	ASN107
A	ALA111
A	VAL233
A	ASN237
A	OLB518

---

site_id	AD7
Number of Residues	2
Details	binding site for residue OLB A 516

Chain	Residue
A	ILE199
A	HOH671

---

site_id	AD8
Number of Residues	6
Details	binding site for residue OLB A 517

Chain	Residue
A	PHE343
A	ILE346
A	THR411
A	PHE412
A	PHE417
A	OLC545

---

site_id	AD9
Number of Residues	4
Details	binding site for residue OLB A 518

Chain	Residue
A	ASN237
A	PHE241
A	OLB515
A	HOH611

---

site_id	AE1
Number of Residues	2
Details	binding site for residue OLB A 519

Chain	Residue
A	LEU126
A	OLC532

---

site_id	AE2
Number of Residues	6
Details	binding site for residue OLB A 520

Chain	Residue
A	ASP289
A	LYS292
A	THR293
A	PHE296
A	TYR462
A	OLC551

---

site_id	AE3
Number of Residues	3
Details	binding site for residue OLB A 521

Chain	Residue
A	SER301
A	OLC547
A	OLC551

---

site_id	AE4
Number of Residues	3
Details	binding site for residue OLC A 522

Chain	Residue
A	LEU94
A	PHE218
A	PHE219

---

site_id	AE5
Number of Residues	3
Details	binding site for residue OLC A 523

Chain	Residue
A	PHE206
A	THR207
A	ILE208

---

site_id	AE6
Number of Residues	5
Details	binding site for residue OLC A 524

Chain	Residue
A	TYR99
A	PHE100
A	PHE101
A	GLU103
A	LYS122

---

site_id	AE7
Number of Residues	5
Details	binding site for residue OLC A 525

Chain	Residue
A	ILE167
A	TYR175
A	SER179
A	ILE182
A	HOH604

---

site_id	AE8
Number of Residues	6
Details	binding site for residue OLC A 527

Chain	Residue
A	TRP153
A	PRO154
A	THR157
A	SER194
A	ILE195
A	HOH706

---

site_id	AE9
Number of Residues	5
Details	binding site for residue OLC A 528

Chain	Residue
A	THR437
A	ASN439
A	TRP442
A	ILE445
A	LEU448

---

site_id	AF1
Number of Residues	2
Details	binding site for residue OLC A 529

Chain	Residue
A	THR360
A	OLC541

---

site_id	AF2
Number of Residues	7
Details	binding site for residue OLC A 530

Chain	Residue
A	THR224
A	PHE364
A	ALA367
A	THR368
A	SER371
A	LEU372
A	HOH617

---

site_id	AF3
Number of Residues	2
Details	binding site for residue OLC A 531

Chain	Residue
A	TYR385
A	LEU392

---

site_id	AF4
Number of Residues	2
Details	binding site for residue OLC A 532

Chain	Residue
A	OLB519
A	HOH604

---

site_id	AF5
Number of Residues	7
Details	binding site for residue OLC A 533

Chain	Residue
A	ILE19
A	PHE315
A	PHE316
A	HIS319
A	GLU440
A	CA509
A	HOH655

---

site_id	AF6
Number of Residues	1
Details	binding site for residue OLC A 534

Chain	Residue
A	ILE186

---

site_id	AF7
Number of Residues	2
Details	binding site for residue OLC A 535

Chain	Residue
A	LYS332
A	LEU392

---

site_id	AF8
Number of Residues	1
Details	binding site for residue OLC A 536

Chain	Residue
A	PHE23

---

site_id	AF9
Number of Residues	2
Details	binding site for residue OLC A 538

Chain	Residue
A	TYR204
A	HOH711

---

site_id	AG1
Number of Residues	1
Details	binding site for residue OLC A 539

Chain	Residue
A	THR224

---

site_id	AG2
Number of Residues	1
Details	binding site for residue OLC A 541

Chain	Residue
A	OLC529

---

site_id	AG3
Number of Residues	1
Details	binding site for residue OLC A 542

Chain	Residue
A	OLC552

---

site_id	AG4
Number of Residues	1
Details	binding site for residue OLC A 543

Chain	Residue
A	TYR99

---

site_id	AG5
Number of Residues	4
Details	binding site for residue OLC A 545

Chain	Residue
A	ILE306
A	ILE335
A	PHE343
A	OLB517

---

site_id	AG6
Number of Residues	1
Details	binding site for residue OLC A 547

Chain	Residue
A	OLB521

---

site_id	AG7
Number of Residues	1
Details	binding site for residue OLC A 548

Chain	Residue
A	PHE206

---

site_id	AG8
Number of Residues	2
Details	binding site for residue OLC A 550

Chain	Residue
A	SER408
A	OLC552

---

site_id	AG9
Number of Residues	3
Details	binding site for residue OLC A 551

Chain	Residue
A	OLB520
A	OLB521
A	OLC553

---

site_id	AH1
Number of Residues	4
Details	binding site for residue OLC A 552

Chain	Residue
A	ILE369
A	TYR404
A	OLC542
A	OLC550

---

site_id	AH2
Number of Residues	3
Details	binding site for residue OLC A 553

Chain	Residue
A	VAL268
A	VAL271
A	OLC551

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	74
Details	Topological domain: {"description":"Periplasmic","evidences":[{"source":"PubMed","id":"28024149","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	265
Details	Transmembrane: {"description":"Helical","evidences":[{"source":"PubMed","id":"28024149","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	73
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"28024149","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---