5T6F
1.90 A resolution structure of Norovirus 3CL protease in complex with the dipeptidyl inhibitor 7l (orthorhombic P form)
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | binding site for residue N38 A 201 |
| Chain | Residue |
| A | HIS30 |
| A | HIS157 |
| A | ALA158 |
| A | ALA159 |
| A | ALA160 |
| A | HOH309 |
| A | GLU54 |
| A | ILE109 |
| A | GLN110 |
| A | ARG112 |
| A | THR134 |
| A | ILE135 |
| A | PRO136 |
| A | CYS139 |
| site_id | AC2 |
| Number of Residues | 15 |
| Details | binding site for Di-peptide N38 B 201 and CYS B 139 |
| Chain | Residue |
| B | GLY15 |
| B | TRP16 |
| B | HIS30 |
| B | GLU54 |
| B | ARG112 |
| B | VAL114 |
| B | THR134 |
| B | GLY137 |
| B | ASP138 |
| B | GLY140 |
| B | ALA141 |
| B | HIS157 |
| B | ALA158 |
| B | ALA159 |
| B | ALA160 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | Active site: {"description":"For 3CLpro activity","evidences":[{"source":"PROSITE-ProRule","id":"PRU00870","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"16641296","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23365454","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
